Page 58 - JCBP-2-4

Journal of Clinical and
Basic Psychosomatics Schizophrenia and metabolism

levels, and abnormal blood lipid profiles, frequently 2. Methods
referred to as insulin resistance syndrome. In SZ patients,
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the incidence of MS is 2 – 3 times higher compared to 2.1. Search strategy
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the general population. The exact etiology of MS in SZ The Web of Science database serves as a prominent
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patients remains elusive, although numerous studies have academic resource for bibliometric analysis. In this study,
implicated it as a consequence of side effects associated with we conducted a comprehensive search within the Web
second-generation antipsychotic drugs such as clozapine of Science Core Collection database, covering literature
and olanzapine. SZ patients with MS often experience related to SZ and MS up to August 15, 2023. Our search
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more pronounced cognitive impairments, with a markedly strategy incorporated the following terms: TS = (SZ OR SZs
increased risk of coronary artery disease, cerebrovascular OR Schizophrenic Disorders OR Disorder, Schizophrenic
disease, congestive heart failure, and cardiovascular-related OR Dementia Praecox) AND TS = (MS OR MSs OR
mortality; death in people with SZ is significantly higher Syndrome, Metabolic OR Syndromes, metabolic OR
than that the normal population, second only to suicide as Insulin Resistance Syndrome). Due to technical and
a cause of death among SZ patients. 7 copyright reasons, we only included all related literature
within the Web of Science Core Collection database. The
Bibliometrics, a comprehensive methodology relevant articles were subsequently exported and stored
encompassing both quantitative and qualitative approaches, in the form of plain.txt, comprising full records and cited
plays a pivotal role in analyzing scientific literature. The references, to facilitate further analyses.
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bibliometrics currently used can usually be divided into
two categories: evaluative and relational. Evaluative 2.2. Data analysis
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bibliometrics is used to describe the characteristics and To conduct this bibliometric analysis, we employed a range
integration results of published information. The most of specialized software tools and resources. These included
common forms of evaluative bibliometrics are systematic R (version 4.0.4, R Foundation for Statistical Computing,
reviews and meta-analyses. Relational bibliometrics Vienna, Austria), VOSviewer (version 1.6.17, Leiden
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provides an overview of the relationships between different University, Britain), CiteSpace Software (6.1.R2, The
participants. The idea behind relational bibliometrics is College of Information Science and Technology, Drexel
that hidden associations can be identified in the metadata University, America), and Pajek and online bibliometrics
collected from various entities, which helps to understand website (https://bibliometric.com/). The R package,
entity sets at a broader level. It can realize frequently cited a versatile tool for quantitative bibliometric research,
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research, keywords, and collaborative networks involving was utilized for (1) summarizing the total number of
countries, institutions, and authors in specific research publications per year and annual publication volumes for
fields, which help to discover hotspots and shortcomings each country; (2) identifying authors, institutions, and
in related fields. In research, one can employ pertinent journals with the highest publication counts and impact;
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bibliometric methods as required, including the use (3) tracking the annual cumulative occurrences of top
of bibliometric coupling. Once the research topic is keywords/terms and references; (4) calculating production
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identified, a thorough search is conducted on relevant and cooperation frequencies among countries; and
academic platforms such as PubMed, utilizing specific (5) creating a visual representation in the form of a three-
search queries and years. The retrieved articles are then field plot highlighting keywords, references, and authors.
imported into dedicated bibliometric software, such as R
software, Citespace, online bibliometrics website, and VOSviewer is a specialized software application
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VOSviewer for analysis, followed by targeted refinement designed for the visualization of bibliometric networks.
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and adjustment according to the desired outcomes. 13 It excels at organizing interconnected nodes into distinct
clusters, with the nodes of the same hue representing a
Bibliometrics has been applied in the research on the stronger correlation. In this study, VOSviewer was used
relationship between SZ and oxidative stress, as well to perform: (1) exploration the collaborative network of
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as between SZ and inflammation, and the articles have authors and their institutions and (2) literature co-citation
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received widespread attention. However, the burgeoning analysis and keyword co-occurrence network analysis. For
incidence of MS in SZ patients and the associated body the study of intricate nonlinear networks, we utilized Pajek,
of literature have yet to undergo a systematic analysis. a robust and large-scale complex network analysis tool. It
Addressing this knowledge gap, this bibliometric allowed us to enhance images previously processed using
analysis endeavors to construct a comprehensive map of VOSviewer and subjected them to further comprehensive
scientific publications pertaining to the intersection of analyses. In addition, the freely available Java program
SZ and MS. CiteSpace played a central role in our research by

Volume 2 Issue 4 (2024) 2 doi: 10.36922/jcbp.4238