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Journal of Clinical and

                                                                   Basic Psychosomatics




                                        REVIEW ARTICLE
                                        Psychosomatic influences on

                                        insomnia: Mechanisms, diagnosis, and treatment
                                        strategies



                                                                 1
                                                                                        1,2
                                        Alejandro Camacho-Zamora , Josué Camberos-Barraza ,
                                                              1,2
                                                                                     1,3
                                        Ángel R. Rábago-Monzón , Hugo J. Sosa-Arámbula , and
                                                                 1
                                        Alberto K. De la Herrán-Arita *
                                        1 Facultad de Medicina, Universidad Autónoma de Sinaloa, Culiacán, México
                                        2 Doctorado en Ciencias en Biomedicina Molecular, Universidad Autónoma de Sinaloa, Culiacán,
                                        Sinaloa, México
                                        3 Maestría en Ciencias en Biomedicina Molecular, Universidad Autónoma de Sinaloa, Culiacán,
                                        Sinaloa, México



                                        Abstract
                                        Insomnia is the most prevalent sleep disorder with significant implications for mental
                                        and physical health.  While traditionally understood through a biomedical lens,
            *Corresponding author:      increasing evidence highlights the role of psychosomatic factors in its onset and
            Alberto K. De la Herrán-Arita
            (alberto.kousuke@uas.edu.mx)  perpetuation. This narrative review explores the relationship between psychological
                                        and somatic influences on insomnia, examining the underlying mechanisms, diagnostic
            Citation: Camacho-Zamora A,   challenges, and treatment strategies. We discuss neurobiological pathways, including
            Camberos-Barraza J,
            Rábago-Monzón AR,           the hypothalamic–pituitary–adrenal axis and neurotransmitter imbalances, alongside
            Sosa-Arámbula HJ, and       psychological factors such as anxiety, hyperarousal, and cognitive distortions. Somatic
            De la Herrán-Arita AK.      symptoms, particularly chronic pain, and other physical conditions are also regarded
            Psychosomatic influences on
            insomnia: Mechanisms, diagnosis,   as integral contributors to insomnia. Diagnosis of psychosomatic insomnia requires
            and treatment strategies. J Clin   a comprehensive approach that incorporates both psychological and physical
            Basic Psychosom. 2025;3(1):32-51.   assessments, utilizing a combination of clinical interviews, standardized questionnaires,
            doi: 10.36922/jcbp.4588
                                        and differential diagnostic techniques. Treatment strategies are discussed in this paper
            Received: August 20, 2024   with an emphasis on cognitive-behavioral therapy for insomnia, pharmacological
            1st revised: October 23, 2024  interventions, and integrative approaches that address the multifaceted nature of the
                                        disorder. The review also highlights the importance of lifestyle modifications and the
            2nd revised: November 1, 2024
                                        potential role of alternative therapies in managing insomnia. A rounded understanding
            Accepted: November 14, 2024  of psychosomatic influences is crucial for effective diagnosis and treatment of
            Published Online: December 3,   insomnia. Future research should focus on personalized therapeutic approaches and
            2024                        further interpreting the complex interconnections between mind and body in the
            Copyright: © 2024 Author(s).   pathophysiology of insomnia. This perspective has the potential to enhance clinical
            This is an Open-Access article   practice and improve outcomes for individuals suffering from this challenging disorder.
            distributed under the terms of the
            Creative Commons Attribution
            License, permitting distribution,   Keywords: Insomnia; Sleep–wake cycle; Somatization; Stress
            and reproduction in any medium,
            provided the original work is
            properly cited.
            Publisher’s Note: AccScience
            Publishing remains neutral with   1. Introduction
            regard to jurisdictional claims in
            published maps and institutional   Insomnia is a common yet complex sleep disorder, characterized by difficulties in
            affiliations.               initiating or maintaining sleep or experiencing non-restorative sleep. These difficulties


            Volume 3 Issue 1 (2025)                         32                              doi: 10.36922/jcbp.4588
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