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Journal of Clinical and
Basic Psychosomatics Depression and chronic pancreatitis: MR study

doi: 10.1002/sim.3034 and bias detection through Egger regression. Int J Epidemiol.
2015;44(2):512-525.
18. Howard DM, Adams MJ, Clarke TK, et al. Genome-wide
meta-analysis of depression identifies 102 independent doi: 10.1093/ije/dyv080
variants and highlights the importance of the prefrontal
brain regions. Nat Neurosci. 2019;22(3):343-352. 29. Brion MJ, Shakhbazov K, Visscher PM. Calculating
statistical power in Mendelian randomization studies. Int J
doi: 10.1038/s41593-018-0326-7 Epidemiol. 2013;42(5):1497-14501.
19. Mao X, Mao S, Sun H, et al. Causal associations between doi: 10.1093/ije/dyt179
modifiable risk factors and pancreatitis: A comprehensive
Mendelian randomization study. Front Immunol. 30. Burgess S, Thompson SG. Multivariable Mendelian
2023;14:1091780. randomization: The use of pleiotropic genetic variants to
estimate causal effects. Am J Epidemiol. 2015;181(4):251-260.
doi: 10.3389/fimmu.2023.1091780
doi: 10.1093/aje/kwu283
20. Skrivankova VW, Richmond RC, Woolf BAR, et al.
Strengthening the reporting of observational studies in 31. Rees JMB, Wood AM, Burgess S. Extending the MR-Egger
epidemiology using mendelian randomisation (STROBE-MR): method for multivariable Mendelian randomization to
explanation and elaboration. BMJ. 2021;375:n2233. correct for both measured and unmeasured pleiotropy. Stat
Med. 2017;36(29):4705-4718.
doi: 10.1136/bmj.n2233
doi: 10.1002/sim.7492
21. Skrivankova VW, Richmond RC, Woolf BAR, et al.
Strengthening the reporting of observational studies 32. Verbanck M, Chen CY, Neale B, Do R. Detection of
in epidemiology using mendelian randomization: The widespread horizontal pleiotropy in causal relationships
STROBE-MR statement. JAMA. 2021;326(16):1614-1621. inferred from Mendelian randomization between complex
traits and diseases. Nat Genet. 2018;50(5):693-698.
doi: 10.1001/jama.2021.18236
doi: 10.1038/s41588-018-0099-7
22. Wray NR, Ripke S, Mattheisen M, et al. Genome-wide
association analyses identify 44 risk variants and refine 33. Carter AR, Sanderson E, Hammerton G, et al. Mendelian
the genetic architecture of major depression. Nat Genet. randomisation for mediation analysis: Current methods
2018;50(5):668-681. and challenges for implementation. Eur J Epidemiol.
2021;36(5):465-478.
doi: 10.1038/s41588-018-0090-3
doi: 10.1007/s10654-021-00757-1
23. Howard DM, Adams MJ, Shirali M, et al. Genome-wide
association study of depression phenotypes in UK Biobank 34. Richardson TG, Sanderson E, Palmer TM, et al. Evaluating
identifies variants in excitatory synaptic pathways. Nat the relationship between circulating lipoprotein lipids and
Commun. 2018;9(1):1470. apolipoproteins with risk of coronary heart disease: A
multivariable Mendelian randomisation analysis. PLoS Med.
doi: 10.1038/s41467-018-03819-3 2020;17(3):e1003062.
24. Kurki MI, Karjalainen J, Palta P, et al. FinnGen provides doi: 10.1371/journal.pmed.1003062
genetic insights from a well-phenotyped isolated population.
Nature. 2023;613(7944):508-518. 35. Liu M, Jiang Y, Wedow R, et al. Association studies of
up to 1.2 million individuals yield new insights into the
doi: 10.1038/s41586-022-05473-8 genetic etiology of tobacco and alcohol use. Nat Genet.
25. Hart PA, Conwell DL. Chronic pancreatitis: Managing a 2019;51(2):237-244.
difficult disease. Am J Gastroenterol. 2020;115(1):49-55. doi: 10.1038/s41588-018-0307-5
doi: 10.14309/ajg.0000000000000421 36. Xue A, Wu Y, Zhu Z, et al. Genome-wide association analyses
26. Palmer TM, Lawlor DA, Harbord RM, et al. Using multiple identify 143 risk variants and putative regulatory mechanisms
genetic variants as instrumental variables for modifiable risk for type 2 diabetes. Nat Commun. 2018;9(1):2941.
factors. Stat Methods Med Res. 2012;21(3):223-242. doi: 10.1038/s41467-018-04951-w
doi: 10.1177/0962280210394459 37. Yuan S, Giovannucci EL, Larsson SC. Gallstone
28. Burgess S, Thompson SG. Interpreting findings from disease, diabetes, calcium, triglycerides, smoking and
Mendelian randomization using the MR-Egger method. Eur alcohol consumption and pancreatitis risk: Mendelian
J Epidemiol. 2017;32(5):377-389. randomization study. NPJ Genom Med. 2021;6(1):27.
doi: 10.1007/s10654-017-0255-x doi: 10.1038/s41525-021-00189-6
27. Bowden J, Davey Smith G, Burgess S. Mendelian 38. Rich KL, Abu-El-Haija M, Nathan JD, Lynch-Jordan A. The
randomization with invalid instruments: Effect estimation role of psychology in the care of children with pancreatitis.

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