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Journal of Clinical and
            Translational Research                                              Immunogenicity and safety of flu vaccines



            Figure 3. (Continued)
            D






























































            Figure 3. Forest plot of seroconversion rates for different influenza strains among different vaccine groups. Influenza strains: A/H1N1 strain (A); A/H3N2
            strain (B); B/Victoria strain (C); B/Yamagata strain (D).
            Abbreviations: DL: DerSimonian-Laird; IIV: Inactivated influenza vaccine; CI: Confidence interval.

            other adverse reaction events (pain, redness, chills, fatigue/  4. Discussion
            sleepiness, fever, and vomiting), the incidence rates were
            significantly lower in individuals vaccinated with split IV   Influenza is  one of the major diseases posing a serious
            compared to those vaccinated with adjuvanted subunit IV.  threat to human health. Globally, seasonal influenza





            Volume 11 Issue 3 (2025)                        27                         doi: 10.36922/JCTR025060006
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