Page 63 - MI-1-1

Microbes & Immunity Benefit of noninvasive VNS in vaccine optimization

doi: 10.1111/cen3.12703 A pilot randomized clinical trial. Expert Rev Med Devices.
2022;19(11):915920.
38. Rangon CM, Niezgoda A. Understanding the pivotal role of
the vagus nerve in health from pandemics. Bioengineering. doi: 10.1080/17434440.2022.2154147
2022;9(8):352. 48. Jankauskaite L, Malinauskas M, Mickeviciute GC.
doi: 10.3390/bioengineering9080352 HMGB1: A potential target of nervus vagus stimulation in
pediatric SARS-CoV-2-induced ALI/ARDS. Front Pediatr.
39. Wang Q, Iketani S, Li Z, et al. Alarming antibody evasion 2022;10:884539.
properties of rising SARS-CoV-2 BQ and XBB subvariants.
Cell. 2023;186(2):279-286.e8. doi: 10.3389/fped.2022.884539
doi: 10.1016/j.cell.2022.12.018 49. Chrestia JF, Oliveira AS, Mulholland AJ, Gallagher T,
Bermúdez I, Bouzat C. A Functional interaction between
40. Terliesner N, Unterwalder N, Edelmann A, et al. Viral Y674-R685 region of the SARS-CoV-2 Spike protein
infections in hospitalized children in Germany during the and the human α7 nicotinic receptor. Mol Neurobiol.
COVID-19 pandemic: Association with non-pharmaceutical 2022;59(10):60766090.
interventions. Front Pediatr. 2022;10:935483.
doi: 10.1007/s12035-022-02947-8
doi: 10.3389/fped.2022.935483
50. Doria D, Santin AD, Tuszynski JA, Scheim DE,
41. Jacinto CP, Gastaldi AC, Aguiar DY, Maida KD, Souza HCD. Aminpour M. Omicron SARS-CoV-2 Spike-1 protein’s
Physical therapy for airway clearance improves cardiac decreased binding affinity to α7nAChr: Implications for
autonomic modulation in children with acute bronchiolitis. autonomic dysregulation of the parasympathetic nervous
Braz J Phys Ther. 2013;17(6):533540. system and the cholinergic anti-inflammatory pathway-an
doi: 10.1590/S1413-35552012005000120 in silico analysis. BioMedInformatics. 2022;2(4):553564.
42. Staats P, Giannakopoulos G, Blake J, Liebler E, Levy RM. doi: 10.3390/biomedinformatics2040035
The use of non-invasive vagus nerve stimulation to 51. Woo MS, Shafiq M, Fitzek A, et al. Vagus nerve
treat respiratory symptoms associated with COVID-19: inflammation contributes to dysautonomia in COVID-19.
A theoretical hypothesis and early clinical experience. Acta Neuropathol. 2023;146(3):387394.
Neuromodulation. 2020;23(6):784788.
doi: 10.1007/s00401-023-02612-x
doi: 10.1111/ner.13172
52. Tanmay S, Labrou D, Farsalinos K, Poulas K. Is SARS-CoV-2
43. Seitz T, Szeles JC, Kitzberger R, et al. Percutaneous auricular spike glycoprotein impairing macrophage function via
vagus nerve stimulation reduces inflammation in critical α7-nicotinic acetylcholine receptors? Food Chem Toxicol.
Covid-19 patients. Front Physiol. 2022;13:897257. 2021;152:112184.
doi: 10.3389/fphys.2022.897257 doi: 10.1016/j.fct.2021.112184
44. Tornero C, Pastor E, Garzando MM, et al. Non-invasive 53. Godellas NE, Cymes GD, Grosman C. An experimental test
vagus nerve stimulation for COVID-19: Results from a of the nicotinic hypothesis of COVID-19. Proc Natl Acad Sci
randomized controlled trial (SAVIOR I). Front Neurol. U S A. 2022;119(44):e2204242119.
2022;13:820864.
doi: 10.1073/pnas.2204242119
doi: 10.3389/fneur.2022.820864
54. Zoli M, Pucci S, Vilella A, Gotti C. Neuronal and
45. Rangon CM, Barruet R, Mazouni A, et al. Auricular extraneuronal nicotinic acetylcholine receptors. Curr
neuromodulation for mass vagus nerve stimulation: Neuropharmacol. 2018;16(4):338349.
Insights from SOS COVID-19 a multicentric, randomized,
controlled, double-blind French pilot study. Front Physiol. doi: 10.2174/1570159X15666170912110450
2021;12:704599. 55. Bulfamante G, Bocci T, Falleni M, Campiglio L, Coppola S,
doi: 10.3389/fphys.2021.704599 Tosi D, et al. Brainstem neuropathology in two cases of
COVID-19: SARS-CoV-2 trafficking between brain and
46. Boezaart AP, Botha DA. Treatment of stage 3 COVID-19 lung. J Neurol. 2021;268(12):4486-91.
with transcutaneous auricular vagus nerve stimulation
drastically reduces interleukin-6 blood levels: A report on doi: 10.1007/s00415-021-10604-8
two cases. Neuromodulation. 2021;24(1):166167. 56. Basha S, Surendran N, Pichichero M. Immune responses in
doi: 10.1111/ner.13293 neonates. Expert Rev Clin Immunol. 2014;10(9):11711184.
47. Uehara L, Corrêa JCF, Ritti R, et al. Transcutaneous doi: 10.1586/1744666X.2014.942288
auricular vagus nerve stimulation effects on inflammatory 57. Cooper DM, Afghani B, Byington CL, et al. SARS-CoV-2
markers and clinical evolution of patients with COVID-19: vaccine testing and trials in the pediatric population:

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