Page 96 - MI-1-2
P. 96
Microbes & Immunity Identifying hydrogenase orthologs in the human proteome
10. Ohta S. Molecular hydrogen is a novel antioxidant to ulcerative colitis mice. Adv Med Sci. 2022;67(1):29-38.
efficiently reduce oxidative stress with potential for the doi: 10.1016/j.advms.2021.10.002
improvement of mitochondrial diseases. Biochim Biophys
Acta. 2012;1820(5):586-594. 20. Guo L, Liu M, Duan T. Hydrogen suppresses oxidative
stress by inhibiting the p38 MAPK signaling pathway in
doi: 10.1016/j.bbagen.2011.05.006
preeclampsia. Adv Clin Exp Med. 2023;32(3):357-367.
11. LeBaron TW, Kura B, Kalocayova B, Tribulova N, Slezak J. doi: 10.17219/acem/154623
A new approach for the prevention and treatment of
cardiovascular disorders. Molecular hydrogen significantly 21. Begum R, Kim CS, Fadriquela A, et al. Molecular hydrogen
reduces the effects of oxidative stress. Molecules. protects against oxidative stress-induced RAW 264.7
2019;24(11):2076. macrophage cells through the activation of Nrf2 and
inhibition of MAPK signaling pathway. Mol Cell Toxicol.
doi: 10.3390/molecules24112076
2020;16:103-118.
12. Alharbi AAD, Ebine N, Nakae S, Hojo T, Fukuoka Y.
Application of molecular hydrogen as an antioxidant in doi: 10.1007/s13273-020-00074-w
responses to ventilatory and ergogenic adjustments during 22. Lane N. Why are cells powered by proton gradients? Nat
incremental exercise in humans. Nutrients. 2021;13(2):459. Educ. 2010;3(9):2.
doi: 10.3390/nu13020459 doi: 10.1038/46903
13. Artamonov MY, Martusevich AK, Pyatakovich FA, 23. White LM, Bhartia R, Stucky GD, Kanik I, Russell MJ.
Minenko IA, Dlin SV, LeBaron TW. Molecular hydrogen: Mackinawite and greigite in ancient alkaline hydrothermal
From molecular effects to stem cells management and tissue chimneys: Identifying potential key catalysts for emergent
regeneration. Antioxidants. 2023;12(3):636. life. Earth Planet Sci Lett. 2015;100(430):105-114.
doi: 10.3390/antiox12030636 doi: 10.1016/j.epsl.2015.08.013
14. Singh RB, Sumbalova Z, Fatima G, et al. Effects of molecular 24. Piché-Choquette S, Constant P. Molecular hydrogen, a
hydrogen in the pathophysiology and management of neglected key driver of soil biogeochemical processes. Appl
cardiovascular and metabolic diseases. Rev Cardiovasc Med. Envirin Microbiol. 2019;85(6):e02418-18.
2024;25(1):33.
doi: 10.1128/AEM.02418-18
doi: 10.31083/j.rcm2501033
25. Russell MJ, Ponce A. Six “must-have” minerals for life’s
15. Kucharská J, Gvozdjáková A, Kura B, Rausová Z, Slezák J. emergence: Olivine, pyrrhotite, bridgmanite, serpentine,
Effect of molecular hydrogen on coenzyme Q in plasma, fougerite and mackinawite. Life (Basel). 2020;10(11):291.
myocardial tissue and mitochondria of rats. J Nutr Health doi: 10.3390/life10110291
Food Eng. 2018;8:362-364.
26. Duval S, Zuchan K, Baymann F, et al. Minerals and the
doi: 10.15406/jnhfe.2018.08.00296
emergence of life. In: Kroneck P, Sosa Torres ME, editors.
16. Iuchi K, Nishimaki K, Kamimura N, Ohta S. Molecular Metals in Life Sciences. Berlin: Springer; 2021. p. 135-157.
hydrogen suppresses free-radical-induced cell death by
mitigating fatty acid peroxidation and mitochondrial doi: 10.1515/9783110589771-011
dysfunction. Can J Phys Pharm. 2019;97(10):999-1005. 27. Preiner M, Xavier JC, Vieira ADN, Kleinermanns K, Allen
JF, Martin WF. Catalysts, autocatalysis and the origin of
doi: 10.1139/cjpp-2018-0741
metabolism. Interface Focus. 2019;9(6):20190072.
17. Zhao N, Sun R, Cui Y, et al. High concentration hydrogen doi: 10.1098/rsfs.2019.0072
mitigates sepsis-induced acute lung injury in mice by
alleviating mitochondrial fission and dysfunction. J. Pers 28. Marreiros BC, Batista AP, Duarte AM, Pereira MM.
Med. 2023;13(2):244. A missing link between complex I and group 4 membrane-
bound [NiFe] hydrogenases. Biochim Biophys Acta.
doi: 10.3390/jpm13020244
2013;1827(2):198-209.
18. Yang YX, Fei WY, Liu MS, et al. Molecular hydrogen
promotes adipose-derived stem cell myogenic differentiation doi: 10.1016/j.bbabio.2012.09.012
via regulation of mitochondria. Curr Stem Cell Res Ther. 29. Read AD, Bentley RE, Archer SL, Dunham-Snary KJ.
2023;18(6):864-875. Mitochondrial iron-sulfur clusters: Structure, function,
and an emerging role in vascular biology. Redox Biol.
doi: 10.2174/1574888X17666220926115240
2021;47:102164.
19. Song L, Zhang Y, Zhu C, Ding X, Yang L, Yan H. Hydrogen-
rich water partially alleviate inflammation, oxidative stress doi: 10.1016/j.redox.2021.102164
and intestinal flora dysbiosis in DSS-induced chronic 30. Greening C, Biswas A, Carere CR, et al. Genomic and
Volume 1 Issue 2 (2024) 90 doi: 10.36922/mi.4544

