Page 113 - MI-2-2

Microbes & Immunity Big data and DNN-based DTI model in CHP

doi: 10.1159/000237207 79. Seder RA, Gazzinelli R, Sher A, Paul WE. Interleukin 12 acts
directly on CD4 T cells to enhance priming for interferon
+
68. Shaw M, Collins BF, Ho LA, Raghu G. Rheumatoid arthritis-
associated lung disease. Eur Respir Rev. 2015;24(135):1-6. gamma production and diminishes interleukin 4 inhibition of
such priming. Proc Natl Acad Sci USA. 1993;90(21):10188-10192.
doi: 10.1183/09059180.00008014
doi: 10.1073/pnas.90.21.10188
69. Bettelli E, Oukka M, Kuchroo VK. T(H)-17 cells in the 80. Wan YY. GATA3: A master of many trades in immune
circle of immunity and autoimmunity. Nat Immunol. regulation. Trends Immunol. 2014;35(6):233-242.
2007;8(4):345-350.
doi: 10.1016/j.it.2014.04.002
doi: 10.1038/ni0407-345
81. Grünig G, Warnock M, Wakil AE, et al. Requirement
70. Smith KA. Interleukin-2: Inception, impact, and for IL-13 independently of IL-4 in experimental asthma.
implications. Science. 1988;240(4856):1169-1176.
Science. 1998;282(5397):2261-2263.
doi: 10.1126/science.3131876
doi: 10.1126/science.282.5397.2261
71. Charo IF, Ransohoff RM. The many roles of chemokines 82. Wills-Karp M, Luyimbazi J, Xu X, et al. Interleukin-13: Central
and chemokine receptors in inflammation. N Engl J Med. mediator of allergic asthma. Science. 1998;282(5397):2258-2261.
2006;354(6):610-621.
doi: 10.1126/science.282.5397.2258
doi: 10.1056/NEJMra052723
83. Wynn TA. Fibrotic disease and the T(H)1/T(H)2 paradigm.
72. Sariban E, Imamura K, Luebbers R, Kufe D. Transcriptional Nat Rev Immunol. 2004;4(8):583-594.
and posttranscriptional regulation of tumor necrosis
factor gene expression in human monocytes. J Clin Invest. doi: 10.1038/nri1412
1988;81(5):1506-1510. 84. Rittirsch D, Flierl MA, Ward PA. Harmful molecular
doi: 10.1172/jci113482 mechanisms in sepsis. Nat Rev Immunol. 2008;8(10):776-787.
73. Mosmann TR, Cherwinski H, Bond MW, Giedlin MA, doi: 10.1038/nri2402
Coffman RL. Two types of murine helper T cell clone. I. 85. Raghu G, Collard HR, Egan JJ, et al. An official ATS/ERS/
Definition according to profiles of lymphokine activities and JRS/ALAT statement: Idiopathic pulmonary fibrosis:
secreted proteins. J Immunol. 1986;136(7):2348-2357. Evidence-based guidelines for diagnosis and management.
74. Zhu J, Paul WE. Peripheral CD4 T-cell differentiation Am J Respir Crit Care Med. 2011;183(6):788-824.
+
regulated by networks of cytokines and transcription factors. doi: 10.1164/rccm.2009-040GL
Immunol Rev. 2010;238(1):247-262.
86. NHS. Azathioprine: A Medicine for Conditions Affecting
doi: 10.1111/j.1600-065X.2010.00951.x the Immune system. Available from: https://www.nhs.uk/
75. Jones SA, Jenkins BJ. Recent insights into targeting the IL-6 medicines/azathioprine [Last accessed on 2025 Mar 27].
cytokine family in inflammatory diseases and cancer. Nat 87. Anvar MT, Rashidan K, Arsam N, et al. Th17 cell function
Rev Immunol. 2018;18(12):773-789. in cancers: Immunosuppressive agents or anti-tumor allies?
doi: 10.1038/s41577-018-0066-7 Cancer Cell Int. 2024;24:355.
76. Lee AY, Eri R, Lyons AB, Grimm MC, Korner H. CC doi: 10.1186/s12935-024-03525-9
chemokine ligand 20 and its cognate receptor CCR6 in 88. Oldham JM, Lee C, Valenzi E, et al. Azathioprine response
mucosal T cell immunology and inflammatory bowel disease: in patients with fibrotic connective tissue disease-associated
Odd couple or axis of evil? Front Immunol. 2013;4:194. interstitial lung disease. Respir Med. 2016;121:117-122.
doi: 10.3389/fimmu.2013.00194 doi: 10.1016/j.rmed.2016.11.007
77. Schroder K, Hertzog PJ, Ravasi T, Hume DA. Interferon- 89. Morisset J, Johannson KA, Vittinghoff E, et al. Mycophenolate
gamma: An overview of signals, mechanisms and functions. mofetil and azathioprine in chronic hypersensitivity
J Leukoc Biol. 2004;75(2):163-189. pneumonitis. Eur Respir J. 2016;48(Suppl 60):PA3885.
doi: 10.1189/jlb.0603252 doi: 10.1183/13993003.congress-2016.PA3885
78. Arora P, Verma G, Chauhan M, Ahuja A. Atypical protean 90. Alberti ML, Rincon-Alvarez E, Buendia-Roldan I, Selman M.
manifestations of cutaneous sarcoidosis. Indian J Dermatol. Hypersensitivity pneumonitis: Diagnostic and therapeutic
2022;67(1):87-89. challenges. Front Med (Lausanne). 2021;8:718299.
doi: 10.4103/ijd.ijd_379_21 doi: 10.3389/fmed.2021.718299

Volume 2 Issue 2 (2025) 105 doi: 10.36922/mi.4620