Page 7 - MSAM-3-1

Materials Science in

Additive Manufacturing

REVIEW ARTICLE
Porous titanium alloys for medical application:

Progress in preparation process and surface
modification research

4
3
1,2
3
Binghao Wang , Miao Luo , Zheng Shi , Yuwei Cui , Yuting Lv ,
1,2
Chengliang Yang 1,2,4 *, and Liqiang Wang *
4,5
1 Life Sciences and Clinical Medicine Research Centre, Affiliated Hospital of Youjiang Medical
University for Nationalities, Baise, Guangxi, China
2 Guangxi Key Laboratory for Preclinical and Translational Research of Bone and Joint Degenerative
Diseases, Guangxi Biomedical Materials Engineering Research Center for Bone and Joint
Degenerative Diseases, Baise, Guangxi, China
3 College of Mechanical and Electronic Engineering, Shandong University of Science and Technology,
Qingdao, Shandong, China
4 State Key Laboratory of Metal Matrix Composites, Shanghai Jiao Tong University, Shanghai, China
5 National Center for Translational Medicine, Shanghai Jiao Tong University, Shanghai, China

Abstract

Excellent mechanical properties and biocompatibility are the most sought-after
attributes in biomedical materials for the regeneration of damaged tissues. However,
conventional dense titanium alloys possess a modulus significantly higher than that of
*Corresponding authors: human tissues, leading to potential stress-shielding effects. Medical porous titanium
Chengliang Yang
(stbyyl@126.com) alloys can reduce the elastic modulus of the material, promote tissue fixation and
Liqiang Wang vascular regeneration, and improve the suitability for human tissue properties. With the
(Wang_liqiang@sjtu.edu.cn) continuous development of technology, the preparation process of porous titanium
Citation: Wang B, Luo M, Shi Z, alloys has undergone a series of multifaceted transformations and improvements in the
et al. Porous titanium alloys for aspects of powder sintering, fiber preparation, and additive manufacturing processes,
medical application: Progress in
preparation process and surface and its structural characteristics and mechanical properties are constantly evolving
modification research. Mater Sci in a controllable direction. Alongside the enhancement of the material’s mechanical
Add Manuf. 2024;3(1):2753. properties through porous design, optimization of the properties at the implant-tissue
doi: 10.36922/msam.2753 interface also leads to improved antimicrobial and osteogenic properties of porous
Received: January 16, 2024 titanium. Due to the complex internal structure of porous titanium alloys, surface
Accepted: March 8, 2024 modification is mainly carried out in fluid media, which is realized by morphological
modification and the introduction of functional substances. Over time, the surface
Published Online: March 28, 2024 modification of porous titanium alloys for medical applications has progressed from
Copyright: © 2024 Author(s). morphological modification and introduction of chemical composition to the loading
This is an Open Access article of bioactive substances. This evolution aims to enhance safety and efficiency in the
distributed under the terms of the
Creative Commons Attribution use of these materials. This paper reviews the preparation and surface modification
License, permitting distribution, processes of porous titanium alloys for medical use and summarizes the advantages,
and reproduction in any medium, disadvantages, and influencing factors among different processes, with a view to
provided the original work is
properly cited. providing new ideas for the development of porous implants for medical use.
Publisher’s Note: AccScience
Publishing remains neutral with Keywords: Medical implants; Porous titanium alloy; Preparation process; Surface
regard to jurisdictional claims in
published maps and institutional modification
affiliations.

Volume 3 Issue 1 (2024) 1 https://doi.org/10.36922/msam.2753