Page 61 - OR-1-1

29. Takebe T, Sekine K, Enomura M, et al. Vascularized and 41. Sheng Y, Gao J, Yin ZZ, Kang J, Kong Y. Dual-drug delivery
functional human liver from an iPSC-derived organ bud system based on the hydrogels of alginate and sodium
transplant. Nature. 2013;499:481-484. carboxymethyl cellulose for colorectal cancer treatment.
Carbohydr Polym. 2021;269:118325.
doi: 10.1038/nature12271
doi: 10.1016/j.carbpol.2021.118325
30. Taguchi A, Kaku Y., Ohmori T, et al. Redefining the
in vivo origin of metanephric nephron progenitors enables 42. Kim YE, Choi SW, Kim MK, Nguyen TL, Kim J. Therapeutic
generation of complex kidney structures from pluripotent hydrogel patch to treat atopic dermatitis by regulating
stem cells. Cell Stem Cell. 2014;14:53-67. oxidative stress. Nano Lett. 2022;22:2038-2047.
doi: 10.1016/j.stem.2013.11.010 doi: 10.1021/acs.nanolett.1c04899
31. Lee J, Rabbani CC, Gao H, et al. Hair-bearing human skin 43. Mohamed MA, Fallahi A, El-Sokkary AMA, et al.
generated entirely from pluripotent stem cells. Nature. Stimuli-responsive hydrogels for manipulation of cell
2020;582:399-404. microenvironment: From chemistry to biofabrication
technology. Prog Polym Sci. 2019;98:101147.
doi: 10.1038/s41586-020-2352-3
doi: 10.1016/j.progpolymsci.2019.101147
32. Guo X, Liu B, Zhang Y, et al. Decellularized extracellular
matrix for organoid and engineered organ culture. J Tissue 44. Liu H, Wang Y, Cui K, Guo Y, Zhang X, Qin J. Advances in
Eng. 2024;15:20417314241300386. hydrogels in organoids and organs‐on‐a‐chip. Adv Mater.
2019;31:1902042.
doi: 10.1177/20417314241300386
doi: 10.1002/adma.201902042
33. Kozlowski MT, Crook CJ, Ku HT. Towards organoid culture
without Matrigel. Commun Biol. 2021;4:1387. 45. Wu S, Wu X, Wang X, Su J. Hydrogels for bone organoid
construction: From a materiobiological perspective. J Mater
doi: 10.1038/s42003-021-02910-8
Sci Technol. 2023;136:21-31.
34. Aisenbrey EA, Murphy WL. Synthetic alternatives to
Matrigel. Nat Rev Mater. 2020;5:539-551. doi: 10.1016/j.jmst.2022.07.008
46. Takahashi T. Organoids for drug discovery and personalized
doi: 10.1038/s41578-020-0199-8
medicine. Annu Rev Pharmacol Toxicol. 2019;59:447-462.
35. Soliman BG, Nguyen AK, Gooding JJ, Kilian KA. Advancing doi: 10.1146/annurev-pharmtox-010818-021108
synthetic hydrogels through nature‐inspired materials
chemistry. Adv Mater. 2024;36:2404235. 47. Lindeboom RG, Van Voorthuijsen L, Oost KC,
et al. Integrative multi‐omics analysis of intestinal organoid
doi: 10.1002/adma.202404235
differentiation. Mol Syst Biol. 2018;14:e8227.
36. Li Y, Xiao Y, Liu C. The horizon of materiobiology: A doi: 10.15252/msb.20188227
perspective on material-guided cell behaviors and tissue
engineering. Chem Rev. 2017;117:4376-4421. 48. Shinde SS, Mate GD, Mali SS, Naikwadi ND, Abuzar M,
Sarkate AP. Systems biology approaches for autoimmune
doi: 10.1021/acs.chemrev.6b00654
diseases. In: Systems biology approaches: Prevention,
37. Gan Z, Qin X, Liu H, Liu J, Qin, J. Recent advances in defined diagnosis, and understanding mechanisms of complex
hydrogels in organoid research. Bioact Mater. 2023;28: diseases. Germany: Springer Nature; 2024. p. 299-319.
386-401.
49. Zhang W, Li J, Zhou J, Rastogi A, Ma S. Translational organoid
doi: 10.1016/j.bioactmat.2023.06.004 technology-the convergence of chemical, mechanical,
and computational biology. Trends Biotechnol. 2022;40:
38. Li C, An N, Song Q, et al. Enhancing organoid culture:
Harnessing the potential of decellularized extracellular 1121-1135.
matrix hydrogels for mimicking microenvironments. J doi: 10.1016/j.tibtech.2022.03.003
Biomed Sci. 2024;31:96.
50. Del Sol A, Jung S. The importance of computational modeling
doi: 10.1186/s12929-024-01086-7 in stem cell research. Trends Biotechnol. 2021;39:126-136.
39. Ohnsorg ML, Hushka EA, Anseth KS. Photoresponsive doi: 10.1016/j.tibtech.2020.07.006
chemistries for user-directed hydrogel network modulation 51. Vorontsov E, Bozkurt A, Casson A, et al. A foundation model
to investigate cell-matrix interactions. Acc Chem Res. for clinical-grade computational pathology and rare cancers
2109;252.
detection. Nat Med. 2024;30:2924-2935.
doi: 10.1021/acs.accounts.4c00548
doi: 10.1038/s41591-024-03141-0
40. Joshi N, Yan J, Levy S, et al. Towards an arthritis flare- 52. Qin X, Tape CJ. Deciphering organoids: High-dimensional
responsive drug delivery system. Nat Commun. 2018;9:1275.
analysis of biomimetic cultures. Trends Biotechnol.
doi: 10.1038/s41467-018-03691-1 2021;39:774-787.

Volume 1 Issue 1 (2025) 14 doi: 10.36922/OR025040007