Page 141 - OR-1-3
P. 141
56. Taguchi A, Kaku Y, Ohmori T, et al. Redefining the in vivo with tendons or tenocytes can program amniotic epithelial
origin of metanephric nephron progenitors enables cells towards stepwise tenogenic differentiation. PLoS One.
generation of complex kidney structures from pluripotent 2012;7(2):e30974.
stem cells. Cell Stem Cell. 2014;14(1):53-67.
doi: 10.1371/journal.pone.0030974
doi: 10.1016/j.stem.2013.11.010
68. Zhang C, Zhang E, Yang L, et al. Histone deacetylase inhibitor
57. Huch M, Bonfanti P, Boj SF, et al. Unlimited in vitro treated cell sheet from mouse tendon stem/progenitor cells
expansion of adult bi-potent pancreas progenitors through promotes tendon repair. Biomaterials. 2018;172:66-82.
the Lgr5/R-spondin axis. EMBO J. 2013;32(20):2708-2721.
doi: 10.1016/j.biomaterials.2018.03.043
doi: 10.1038/emboj.2013.204
69. Qin TW, Sun YL, Thoreson AR, et al. Effect of mechanical
58. Zhang Y, Li D, Liu Y, et al. 3D-bioprinted anisotropic stimulation on bone marrow stromal cell-seeded tendon
bicellular living hydrogels boost osteochondral regeneration slice constructs: A potential engineered tendon patch for
via reconstruction of cartilage-bone interface. Innovation rotator cuff repair. Biomaterials. 2015;51:43-50.
(Camb). 2024;5(1):100542.
doi: 10.1016/j.biomaterials.2015.01.070
doi: 10.1016/j.xinn.2023.100542
70. Zhao LL, Luo JJ, Cui J, et al. Tannic acid-modified
59. Kratochvil MJ, Seymour AJ, Li TL,Paşca SP, Kuo CJ, decellularized tendon scaffold with antioxidant and anti-
Heilshorn SC. Engineered materials for organoid systems. inflammatory activities for tendon regeneration. ACS Appl
Nat Rev Mater. 2019;4(9):606-622. Mater Interfaces. 2024;16(13):15879-15892.
doi: 10.1038/s41578-019-0129-9 doi: 10.1021/acsami.3c19019
60. Zhu YJ, Sun LY, Wu XY, Gu ZF, Zhao YJ. Engineered human 71. Alberti KA, Xu Q. Biocompatibility and degradation of
organoids for biomedical applications. Adv Funct Mater. tendon-derived scaffolds. Regen Biomater. 2016;3(1):1-11.
2024;34(11):2310961.
doi: 10.1093/rb/rbv023
doi: 10.1002/adfm.202310961
72. Jiang X, Wu S, Kuss M, et al. 3D printing of multilayered
61. Wang Y, Qin J. Advances in human organoids-on-chips in scaffolds for rotator cuff tendon regeneration. Bioact Mater.
biomedical research. Life Med. 2023;2(1):lnad007.
2020;5(3):636-643.
doi: 10.1093/lifemedi/lnad007
doi: 10.1016/j.bioactmat.2020.04.017
62. Hu Y, Zhang H, Wang S, et al. Bone/cartilage organoid
on-chip: Construction strategy and application. Bioact 73. Rajpar I, Barrett JG. Optimizing growth factor induction of
Mater. 2023;25:29-41. tenogenesis in three-dimensional culture of mesenchymal
stem cells. J Tissue Eng. 2019;10:1-9.
doi: 10.1016/j.bioactmat.2023.01.016
doi: 10.1177/2041731419848776
63. Puschhof J, Pleguezuelos-Manzano C, Clevers H. Organoids
and organs-on-chips: Insights into human gut-microbe 74. Brassard JA, Nikolaev M, Hübscher T, Hofer M, Lutolf MP.
interactions. Cell Host Microbe. 2021;29(6):867-878. Recapitulating macro-scale tissue self-organization through
organoid bioprinting. Nat Mater. 2021;20(1):22-29.
doi: 10.1016/j.chom.2021.04.002
doi: 10.1038/s41563-020-00803-5
64. Shi H, Kowalczewski A, Vu D, et al. Organoid intelligence:
Integration of organoid technology and artificial intelligence 75. Wang D, Zhang X, Huang S, et al. Engineering multi-tissue
in the new era of in vitro models. Med Novel Technol Devices. units for regenerative medicine: Bone-tendon-muscle units
2024;21:100276. of the rotator cuff. Biomaterials. 2021;272:120789.
doi: 10.1016/j.medntd.2023.100276 doi: 10.1016/j.biomaterials.2021.120789
65. Chen W, Sun Y, Gu X, et al. Conditioned medium of human 76. Yin Y, Zhou W, Zhu J, et al. Generation of self-organized
bone marrow-derived stem cells promotes tendon-bone neuromusculoskeletal tri-tissue organoids from human
healing of the rotator cuff in a rat model. Biomaterials. pluripotent stem cells. Cell Stem Cell. 2025;32(1):157-171.e8.
2021;271:120714. doi: 10.1016/j.stem.2024.11.005
doi: 10.1016/j.biomaterials.2021.120714 77. Bai L, Zhou D, Li G, Liu J, Chen X, Su J. Engineering bone/
66. Zhang H, Chen Y, Fan C, et al. Cell-subpopulation alteration cartilage organoids: Strategy, progress, and application. Bone
and FGF7 activation regulate the function of tendon stem/ Res. 2024;12(1):66.
progenitor cells in 3D microenvironment revealed by single- doi: 10.1038/s41413-024-00376-y
cell analysis. Biomaterials. 2022;280:121238.
78. Ahn SY. Various strategies of tendon stem/progenitor cell
doi: 10.1016/j.biomaterials.2021.121238
reprogramming for tendon regeneration. Int J Mol Sci.
67. Barboni B, Curini V, Russo V, et al. Indirect co-culture 2024;25(21):11745.
Volume 1 Issue 3 (2025) 21 doi: 10.36922/OR025170016

