Page 162 - OR-1-3
P. 162
15. Foti C, Vellucci C, Santoro A. Regenerative medicine 28. Chen W, Liu D, Lu K, et al. Organoids of musculoskeletal
solutions for rotator cuff injuries in athletes: Indications and system for disease modeling, drug screening, and
outcomes. Sports Med Arthrosc Rev. 2024;32(1):46-50. regeneration. Adv Healthc Mater. 2025;14(9):e2402444.
doi: 10.1097/JSA.0000000000000399 doi: 10.1002/adhm.202402444
16. Lyu X, Wang J, Su J. Intelligent manufacturing for 29. Frontera WR, Ochala J. Skeletal muscle: A brief review of
osteoarthritis organoids. Cell Prolif. 2025;58:e70043. structure and function. Calcif Tissue Int. 2015;96(3):183-195.
doi: 10.1111/cpr.70043 doi: 10.1007/s00223-014-9915-y
17. Wan S, Aregueta Robles U, Poole-Warren L, Esrafilzadeh D. 30. Edouard P, Reurink G, Mackey AL, et al. Traumatic muscle
Advances in 3D tissue models for neural engineering: Self- injury. Nat Rev Dis Primers. 2023;9(56):1-19.
assembled versus engineered tissue models. Biomater Sci. doi: 10.1038/s41572-023-00469-8
2024;12(14):3522-3549.
31. Hinkle ER, Wiedner HJ, Black AJ, Giudice J. RNA processing
doi: 10.1039/d4bm00317a
in skeletal muscle biology and disease. Transcription.
18. Zhao Z, Chen X, Dowbaj AM, et al. Organoids. Nat Rev 2019;10(1):1-20.
Methods Primers. 2022;2:94.
doi: 10.1080/21541264.2018.1558677
doi: 10.1038/s43586-022-00174-y
32. Gao C, Shi Q, Pan X, et al. Neuromuscular organoids model
19. Verstegen MMA, Coppes RP, Beghin A, et al. spinal neuromuscular pathologies in C9orf72 amyotrophic
Clinical applications of human organoids. Nat Med. lateral sclerosis. Cell Rep. 2024;43(3):11381192.
2025;31(2):409-421.
doi: 10.1016/j.celrep.2024.113892
doi: 10.1038/s41591-024-03489-3
33. Shin MK, Bang JS, Lee JE, et al. Generation of skeletal
20. Xiang Y, Tanaka Y, Cakir B, et al. hESC-derived thalamic muscle organoids from human pluripotent stem cells to
organoids form reciprocal projections when fused with model myogenesis and muscle regeneration. Int J Mol Sci.
cortical organoids. Cell Stem Cell. 2019;24(3):487-497.e7. 2022;23(9):5108.
doi: 10.1016/j.stem.2018.12.015 doi: 10.3390/ijms23095108
21. Shinozawa T, Kimura M, Cai Y, et al. High-fidelity drug- 34. Ebrahimi M, Lad H, Fusto A, et al. De novo revertant
induced liver injury screen using human pluripotent fiber formation and therapy testing in a 3D culture model
stem cell-derived organoids. Gastroenterology. of Duchenne muscular dystrophy skeletal muscle. Acta
2021;160(3):831-846.e10. Biomater. 2021;132:227-244.
doi: 10.1053/j.gastro.2020.10.002 doi: 10.1016/j.actbio.2021.05.020
22. Nugraha B, Buono MF, Von Boehmer L, Hoerstrup SP, 35. Ostrovidov S, Ramalingam M, Bae H, et al. Latest developments
Emmert MY. Human cardiac organoids for disease modeling. in engineered skeletal muscle tissues for drug discovery and
Clin Pharmacol Ther. 2019;105(1):79-85. development. Expert Opin Drug Discov. 2023;18(1):47-63.
doi: 10.1002/cpt.1286 doi: 10.1080/17460441.2023.2160438
23. Little MH, Combes AN. Kidney organoids: Accurate models 36. Grass T, Dokuzluoglu Z, Rodríguez-Muela N. Neuromuscular
or fortunate accidents. Genes Dev. 2019;33(19-20):1319-1345. organoids to study spinal cord development and disease.
doi: 10.1101/gad.329573.119 Methods Mol Biol. 2024;2951:197-219.
24. Almeqdadi M, Mana MD, Roper J, Yilmaz ÖH. Gut organoids: doi: 10.1007/7651_2024_574
Mini-tissues in culture to study intestinal physiology and 37. Li J, Yang Y, Yi Z, et al. Microdroplet-engineered skeletal
disease. Am J Physiol Cell Physiol. 2019;317(3):C405-C419. muscle organoids from primary tissue recapitulate parental
doi: 10.1152/ajpcell.00300.2017 physiology with high reproducibility. Research (Wash D C).
2025;8:0699.
25. Zhang C, Jing Y, Wang J, et al. Skeletal organoids. Biomater
Transl. 2024;5(4):390-410. doi: 10.34133/research.0699
doi: 10.12336/biomatertransl.2024.04.005 38. Yin Y, Zhou W, Zhu J, et al. Generation of self-organized
neuromusculoskeletal tri-tissue organoids from human
26. Corrò C, Novellasdemunt L, Li VSW. A brief history of pluripotent stem cells. Cell Stem Cell. 2025;32(1):157-171.e8.
organoids. Am J Physiol Cell Physiol. 2020;319(1):C151-C165.
doi: 10.1016/j.stem.2024.11.005
doi: 10.1152/ajpcell.00120.2020
39. Shahriyari M, Islam MR, Sakib SM, et al. Engineered
27. Rossi G, Manfrin A, Lutolf MP. Progress and potential in skeletal muscle recapitulates human muscle development,
organoid research. Nat Rev Genet. 2018;19(11):671-687. regeneration and dystrophy. J Cachexia Sarcopenia Muscle.
doi: 10.1038/s41576-018-0051-9 2022;13(6):3106-3121.
Volume 1 Issue 3 (2025) 15 doi: 10.36922/OR025320025

