Page 87 - TD-3-4

Tumor Discovery RNA-protein complexes deregulated in cancer

2014;59:911-923. 54. Ding J, Xie M, Lian Y, et al. Long noncoding RNA HOXA-AS2
represses P21 and KLF2 expression transcription by binding
doi: 10.1002/hep.26740
with EZH2 and LSD1 in colorectal cancer. Oncogenesis.
44. Zhang G, Xu Y, Zou C, et al. The long noncoding RNA 2017;6:e288.
ARHGAP27P1 inhibits gastric cancer cell proliferation and
cell cycle progression by epigenetically regulating p15 and doi: 10.1038/oncsis.2016.84
p16. Aging (Albany NY). 2019;11:9090-9110. 55. Zhang G, Xu Y, Wang S, et al. LncRNA SNHG17 promotes
gastric cancer progression by epigenetically silencing of p15
doi: 10.18632/aging.102377
and p57. J Cell Physiol. 2019;234(4):5163-5174.
45. Bai Z, Wu Y, Bai S, et al. Long noncoding RNA SNHG7
Is activated by SP1 and exerts oncogenic properties by doi: 10.1002/jcp.27320
interacting with EZH2 in ovarian cancer. J Cell Mol Med. 56. Rom A, Melamed L, Gil N, et al. Regulation of CHD2
2020;24:7479-7489. expression by the Chaserr long noncoding RNA gene is
essential for cell viability. Nat Commun. 2019;10:5092.
doi: 10.1111/jcmm.15373
doi: 10.1038/s41467-019-13075-8
46. Huang MD, Chen WM, Qi FZ, et al. Long noncoding
RNA TUG1 is upregulated in hepatocellular carcinoma 57. Jiang X, Li Q, Zhang S, Song C, Zheng P. Long noncoding RNA
and promotes cell growth and apoptosis by epigenetically GIHCG induces cancer progression and chemoresistance
silencing KLF2. Mol Cancer. 2015;14:165. and indicates poor prognosis in colorectal cancer. Onco
Targets Ther. 2019;12:1059-1070.
doi: 10.1186/s12943-015-0431-0
doi: 10.2147/OTT.S192290
47. Ruan J, Zheng L, Hu N, et al. Long noncoding RNA SNHG6
promotes osteosarcoma cell proliferation by regulating p21 58. Li L, Chen J, Wang A, Yi K. ALKBH5 regulates ovarian
and KLF2. Arch Biochem Biophys. 2018;646:128-136. cancer growth via demethylating long noncoding RNA
PVT1 in ovarian cancer. J Cell Mol Med. 2023;28(2):e18066.
doi: 10.1016/j.abb.2018.03.036
doi: 10.1111/jcmm.18066
48. Lian Y, Yang J, Lian Y, Xiao C, Hu X, Xu H. DUXAP8, a
pseudogene-derived lncRNA, promotes the growth of 59. Ma P, Pan Y, Yang F, et al. KLF5-Modulated lncRNA NEAT1
pancreatic carcinoma cells by epigenetically silencing contributes to tumorigenesis by acting as a scaffold for BRG1
CDKN1A and KLF2. Cancer Commun (Lond). 2018;38:64. to silence GADD45A in gastric cancer. Mol Ther Nucleic
Acids. 2020;22:382-395.
doi: 10.1186/s40880-018-0333-9
doi: 10.1016/j.omtn.2020.09.003
49. Chen Z, Chen X, Chen P, et al. Long noncoding RNA
SNHG20 promotes non-small cell lung cancer cell 60. Abildgaard C, do Canto LM, Rainho CA, et al. The long
proliferation and migration by epigenetically silencing of non-coding RNA SNHG12 as a mediator of carboplatin
P21 expression. Cell Death Dis. 2017;8:e3092. resistance in ovarian cancer via epigenetic mechanisms.
Cancers (Basel). 2022;14(7):1664.
doi: 10.1038/cddis.2017.484
doi: 10.3390/cancers14071664
50. Statello L, Guo CJ, Chen LL, Huarte M. Gene regulation by
long noncoding RNAs and its biological functions. Nat Rev 61. Huang X, Chen J, Li H, et al. LncRNA SNHG12 suppresses
Mol Cell Biol. 2021;22:96-118. adipocyte inflammation and insulin resistance by regulating
the HDAC9/Nrf2 axis. FASEB J. 2024;38(13):e23794.
doi: 10.1038/s41580-020-00315-9
doi: 10.1096/fj.202400236RR
51. Cai Z, Cao C, Ji L, et al. RIC-seq for global in situ
profiling of RNA-RNA spatial interactions. Nature. 62. Zhang KJ, Tan XL, Guo L. The long noncoding RNA
2020;582(7812):432-437. DANCR regulates the inflammatory phenotype of breast
cancer cells and promotes breast cancer progression via the
doi: 10.1038/s41586-020-2249-1
EZH2-dependent suppression of SOCS3 transcription. Mol
52. Huang J, Zhou N, Watabe K, et al. Long noncoding RNA Oncol. 2020;14(2):309-328.
UCA1 promotes breast tumor growth by suppressing p27 doi: 10.1002/1878-0261.12622
(Kip1). Cell Death Dis. 2014;5:e1008.
63. Xie F, Huang Q, Wang C, et al. Downregulation of
doi: 10.1038/cddis.2013.541
the long noncoding RNA SNHG14 suppresses cell
53. Luo J, Xiang H. LncRNA MYLK-AS1 acts as an oncogene by proliferation and invasion by regulating EZH2 in pancreatic
epigenetically silencing large tumor suppressor 2 (LATS2) in ductal adenocarcinoma (PDAC). Cancer Biomark.
gastric cancer. Bioengineered. 2021;12:3101-3112. 2020;27(3):357-364.
doi: 10.1080/21655979.2021.1944019 doi: 10.3233/CBM-190908

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