Page 93 - TD-3-4
P. 93
Tumor Discovery RNA-protein complexes deregulated in cancer
doi: 10.1016/j.bbamcr.2018.09.001 181. Chen S, Cao X, Zhang J, Wu W, Zhang B, Zhao F.
circVAMP3 drives CAPRIN1 phase separation and inhibits
170. Shih JW, Wang WT, Tsai TY, Kuo CY, Li HK, Wu Lee YH.
Critical roles of the RNA helicase DDX3 and its interactions hepatocellular carcinoma by suppressing c-Myc translation.
with eIF4E/PABP1 in stress granule assembly and stress Adv Sci (Weinh). 2022;9:e2103817.
response. Biochem J. 2012;441(1):119-129. doi: 10.1002/advs.202103817
doi: 10.1042/BJ20110739 182. Zhang M, Peng S. The association and clinical relevance of
the phase-separating protein CAPRIN1 with noncoding
171. Aditi, Folkmann AW, Wente SR. Cytoplasmic hGle1A
regulates stress granules by modulation of translation. Mol RNA. Cell Stress Chaperones. 2023;28(2):125-132.
Biol Cell. 2015;26(8):1476-1490. doi: 10.1007/s12192-023-01320-5
doi: 10.1091/mbc.E14-11-1523 183. Schneider C, Schneider G. Stress granules-membraneless
organelles as therapeutic targets in pancreatic cancer. EMBO
172. Zhan Y, Chen X, Zheng H, et al. YB1 associates with
oncogenetic roles and poor prognosis in nasopharyngeal Mol Med. 2024;16(3):429-431.
carcinoma. Sci Rep. 2022;12(1):3699. doi: 10.1038/s44321-024-00040-2
doi: 10.1038/s41598-022-07636-z 184. Kim A, Shim S, Kim YH, Kim MJ, Park S, Myung JK.
Inhibition of Y-Box binding protein 1 suppresses cell
173. Cui BC, Sikirzhytski V, Aksenova M, et al. Pharmacological
inhibition of DEAD-Box RNA Helicase 3 attenuates stress growth and motility in colorectal cancer. Mol Cancer Ther.
2020;19(2):479-489.
granule assembly. Biochem Pharmacol. 2020;182:114280.
doi: 10.1158/1535-7163.MCT-19-0265
doi: 10.1016/j.bcp.2020.114280
185. Wang F, Li J, Fan S, et al. Targeting stress granules: A novel
174. Kitajima H, Maruyama R, Niinuma T, et al. TM4SF1-AS1 therapeutic strategy for human diseases. Pharmacol Res.
inhibits apoptosis by promoting stress granule formation in
cancer cells. Cell Death Dis. 2023;14(7):424. 2020;161:105143.
doi: 10.1016/j.phrs.2020.105143
doi: 10.1038/s41419-023-05953-3
186. An S, Huang W, Huang X, et al. Integrative network analysis
175. Kang W, Wang Y, Yang W, Zhang J, Zheng H, Li D. Research
progress on the structure and function of G3BP. Front identifies cell-specific trans regulators of m6A. Nucleic Acids
Res. 2020;48:1715-1729.
Immunol. 2021;12:718548.
doi: 10.1093/nar/gkz1206
doi: 10.3389/fimmu.2021.718548
187. Zhang Y, Jing Y, Wang Y, et al. NAT10 promotes gastric
176. Freibaum BD, Messing J, Nakamura H, et al. Identification cancer metastasis via N4-acetylated COL5A1. Signal
of small molecule inhibitors of G3BP-driven stress granule
formation. J Cell Biol. 2024;223(3):e202308083. Transduct Target Ther. 2021;6:173.
doi: 10.1038/s41392-021-00489-4
doi: 10.1083/jcb.202308083
188. Han J, Liu Q, Zhou Y, Li D, Wang R. Landscape of internal
177. Mukhopadhyay C, Zhou P. Role(s) of G3BPs in human N7-methylguanosine of long noncoding RNA modifications
pathogenesis. J Pharmacol Exp Ther. 2023;387(1):100-110.
in resistant acute myeloid leukemia. BMC Genomics.
doi: 10.1124/jpet.122.001538 2023;24:425.
178. Gal J, Chen J, Na DY, Tichacek L, Barnett KR, Zhu H. doi: 10.1186/s12864-023-09526-8
Acetylation of lysine-376 of G3BP1 regulates RNA 189. Kong Z, Lu Y, Yang Y, et al. m6A-Mediated biogenesis
binding and stress granule dynamics. Mol Cell Biol.
2019;39(22):e00052-19. of circDDIT4 inhibits prostate cancer progression
by sequestrating ELAVL1/HuR. Mol Cancer Res.
doi: 10.1128/MCB.00052-19 2023;21:1342-1355.
179. Lee AK, Klein J, Fon Tacer K, et al. Translational doi: 10.1158/1541-7786.MCR-22-0271
repression of G3BP in cancer and germ cells suppresses 190. Yu XM, Li SJ, Yao ZT, et al. N4-acetylcytidine modification
stress granules and enhances stress tolerance. Mol Cell. of lncRNA CTC-490G23.2 promotes cancer metastasis
2020;79(4):645-659.e9.
through interacting with PTBP1 to increase CD44
doi: 10.1016/j.molcel.2020.06.037 alternative splicing. Oncogene. 2023;42:1101-1116.
180. Li M, Fan X, Zhao J, Wang D. Establishment and validation of doi: 10.1038/s41388-023-02628-3
a four-stress granule-related gene signature in hepatocellular 191. Dou X, Huang L, Xiao Y, et al. METTL14 is a chromatin
carcinoma. J Clin Transl Hepatol. 2024;12(1):1-14.
regulator independent of its RNA N6-methyladenosine
doi: 10.14218/JCTH.2023.00019 methyltransferase activity. Protein Cell. 2023;14(9):683-697.
Volume 3 Issue 4 (2024) 34 doi: 10.36922/td.4657

