Page 97 - TD-4-3
P. 97

Tumor Discovery                                                         Sorafenib induces MVPs in NSCLC



            10.  Sahu RP, Konger RL, Travers JB. Platelet-activating   peroxide. J Biol Chem. 1992;267(21):15168-15175.
               factor-receptor and tumor immunity.  JSM Cell  Dev Biol.      doi: 10.1016/S0021-9258(18)42161-8
               2014;2(1):1008.
                                                               21.  Smiley PL, Patel KD, Stremler KE, Zimmerman GA,
               doi: 10.47739/2379-061X/1008
                                                                  Prescott SM, McIntyre TM. Novel neutrophil agonists:
            11.  Sahu  RP,  Harrison  KA,  Weyerbacher  J,  et al.  Radiation   Oxidatively-fragmented  phosphatidylcholines.  In:
               therapy  generates platelet-activating factor agonists.   Bailey JM, editor. Prostaglandins, Leukotrienes, Lipoxins, and
               Oncotarget. 2016;7(15):20788-20800.                PAF: Mechanism of Action, Molecular Biology, and Clinical
               doi: 10.18632/oncotarget.7878                      Applications. Boston, MA: Springer US; 1991. p. 269-279.
            12.  Sahu RP, Turner MJ, DaSilva SC, et al. The environmental   22.  Fahy K, Liu L, Rapp CM, et al. UVB-generated microvesicle
               stressor ultraviolet B radiation inhibits murine antitumor   particles: A  novel pathway by which a skin-specific
               immunity through its ability to generate platelet-activating   stimulus could exert systemic effects. Photochem Photobiol.
               factor agonists. Carcinogenesis. 2012;33(7):1360-1367.  2017;93(4):937-942.
               doi: 10.1093/carcin/bgs152                         doi: 10.1111/php.12703
            13.  Sahu RP, Ocana JA, Harrison KA, et al. Chemotherapeutic   23.  Maacha S, Bhat AA, Jimenez L, et al. Extracellular vesicles-
               agents subvert tumor immunity by generating agonists of   mediated intercellular communication: Roles in the tumor
               platelet-activating factor. Cancer Res. 2014;74(23):7069-7078.  microenvironment and anti-cancer drug resistance.  Mol
                                                                  Cancer. 2019;18(1):55.
               doi: 10.1158/0008-5472.Can-14-2043
                                                                  doi: 10.1186/s12943-019-0965-7
            14.  Chauhan SJ, Thyagarajan A, Chen Y, Travers JB, Sahu RP.
               Platelet-activating factor-receptor signaling mediates   24.  Muralidharan-Chari  V,  Kohan  HG,  Asimakopoulos  AG,
               targeted therapies-induced microvesicle particles release in   et al. Microvesicle removal of anticancer drugs contributes
               lung cancer cells. Int J Mol Sci. 2020;21(22):8517.  to drug resistance in human pancreatic cancer  cells.
                                                                  Oncotarget. 2016;7(31):50365-50379.
               doi: 10.3390/ijms21228517
                                                                  doi: 10.18632/oncotarget.10395
            15.  Chauhan  SJ,  Thyagarajan  A, Sahu  RP.  Effects  of miRNA-
               149-5p and platelet-activating factor-receptor signaling on   25.  Yang Q, Xu J, Gu J, et al. Extracellular vesicles in cancer drug
               the growth and targeted therapy response on lung cancer   resistance:  Roles,  mechanisms,  and  implications.  Adv Sci.
               cells. Int J Mol Sci. 2022;23(12):6772.            2022;9(34):2201609.
               doi: 10.3390/ijms23126772                          doi: 10.1002/advs.202201609
            16.  Travers  JB, Rohan JG, Sahu RP. New insights into the   26.  Yang Y, Li S, Wang Y, Zhao Y, Li Q. Protein tyrosine kinase
               pathologic roles of the platelet-activating factor system.   inhibitor resistance in malignant tumors: Molecular
               Front Endocrinol (Lausanne). 2021;12:624132.       mechanisms and future perspective. Signal Transduct Target
                                                                  Ther. 2022;7(1):329.
               doi: 10.3389/fendo.2021.624132
                                                                  doi: 10.1038/s41392-022-01168-8
            17.  Bihl JC, Rapp CM, Chen Y, Travers JB. UVB generates
               microvesicle particle release in part due to platelet-activating   27.  Catalano M, O’Driscoll L. Inhibiting extracellular vesicles
               factor signaling. Photochem Photobiol. 2016;92(3):503-506.  formation and release: A review of EV inhibitors. J Extracell
                                                                  Vesicles. 2020;9(1):1703244.
               doi: 10.1111/php.12577
                                                                  doi: 10.1080/20013078.2019.1703244
            18.  Liu L, Awoyemi AA, Fahy KE, et al. Keratinocyte-derived
               microvesicle particles mediate ultraviolet B radiation-  28.  Bianco F, Perrotta C, Novellino L, et al. Acid sphingomyelinase
               induced systemic immunosuppression.  J  Clin Invest.   activity triggers microparticle release from glial cells. EMBO
               2021;131(10):e144963.                              J. 2009;28(8):1043-1054.
               doi: 10.1172/jci144963                             doi: 10.1038/emboj.2009.45
            19.  Thyagarajan A, Kadam SM, Liu L,  et al. Gemcitabine   29.  Deng L, Peng Y, Jiang Y, et al. Imipramine protects against
               induces microvesicle particle release in a platelet-activating   bone loss by inhibition of osteoblast-derived microvesicles.
               factor-receptor-dependent manner via modulation of the   Int J Mol Sci. 2017;18(5):1013.
               MAPK pathway in pancreatic cancer cells.  Int J Mol Sci.      doi: 10.3390/ijms18051013
               2018;20(1):32.
                                                               30.  Kosgodage US, Trindade RP, Thompson PR, Inal JM,
               doi: 10.3390/ijms20010032                          Lange S. Chloramidine/bisindolylmaleimide-i-mediated
            20.  Patel KD, Zimmerman GA, Prescott SM, McIntyre TM. Novel   inhibition of exosome and microvesicle release and
               leukocyte agonists are released by endothelial cells exposed to   enhanced efficacy of cancer chemotherapy.  Int J Mol Sci.


            Volume 4 Issue 3 (2025)                         89                           doi: 10.36922/TD025110019
   92   93   94   95   96   97   98   99   100   101   102