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Artificial Intelligence in Health                                AI model for cardiovascular disease prediction



            a growing challenge to the public healthcare system .   as diagnosis and drug prediction, wearable devices or
                                                        [4]
            According to the World Health Organization, an estimated   implanted sensors for the patient condition monitoring, or
            17 million people die from CVDs each year, particularly   an artificial intelligence (AI) system using neural network
                                [5]
            heart attacks and strokes . The statistics are projected to   (NN), genetic algorithm (GA), fuzzy logic, and many other
                                                                                                        [25]
            reach 22.2 million people by 2030, if CVDs remain the   techniques for the prediction and medical diagnosis .
            leading cause of death and disability worldwide . CVDs are   The Tabu search algorithm is an optimization technique
                                                [6]
            no longer considered an affluent nation’s disease because   that uses adaptive memory to improve the local search for
            the statistics of more than 80% CVD-related deaths were   global optimum performance . This search algorithm
                                                                                       [26]
            contributed by low-and-middle-income countries [7-10] . The   works using a Tabu list to prevent cycling and aspiration
            current clinical guideline for primary prevention of this   criteria for a globally optimal solution and to prevent the
            vascular disease is to identify the asymptomatic patient   repetition of solutions . The present study aims to analyze
                                                                                [27]
            by prognostication and early diagnosis, which help with   the performance of various machine learning techniques,
            the reduction of high-risk CVD patients [11-13] . The heart   such as artificial NNs (ANNs), artificial NN-genetic
            diseases are rapidly increasing in terms of number of cases   algorithms (ANN-GA), support vector machines (SVMs),
            among the young generation but are disproportionately   K-means, K-nearest neighbor (KNN), and decision trees
            affecting men with a mortality rate twice as high than in   (DT), in yielding the best model for CVD prediction. The
            women . Approximately 88,000 deaths can be traced to   motivation of this research is to discover the most effective
                  [14]
            coronary heart disease, while stroke caused about 50,000   machine learning method for detecting CVDs with greater
            deaths and blood circulatory disease 49,000 deaths [15-17] .  precision, sensitivity, and accuracy. The main contributions
              The major risk factors associated with these vascular   of this work to the literature are:
            diseases are age, sex, smoking, family history, cholesterol,   (i)  Development of a hybrid model of ANN-GA for the
            poor diet, high blood pressure, diabetes, obesity, physical   early prediction and diagnosis of CVD.
            inactivity, and alcohol intake . Some symptoms such   (ii)  Comparative analysis of CVD prediction and
                                    [18]
            as chest pain and tiredness are symptomatic indications   diagnosis model using different types of supervised
            aiding in the detection of CVD. However, diagnosing   machine learning techniques, such as ANN, K-means,
            heart diseases is a difficult task in the field of medicine   KNN, and DT.
            because a thorough analysis of patient clinical data and   (iii) Development  of  an  expert  system-based  application
            health history is required. Thus, an intelligent automated   program interface (API) for CVD prediction and
            system for medical diagnosis can help enhance health-  diagnosis.
            care observation and analysis, thereby facilitating the   (iv)  Evaluation of the performance of different machine
            administration of suitable treatment for lifesaving   learning algorithms used for the prediction and
            purposes [19,20] . For the prediction of heart disease, several   diagnosis of CVDs.
            algorithms and diagnostic models have been created to   The remainder of the paper is structured as follows:
            predict heart disease by considering its risk factors, such   the review of related work is presented in Section 2; the
            as arterial high blood pressure, high cholesterol, diabetes   research methodology is described in Section 3, and the
            mellitus, smoking, obesity, unhealthy diet, and a family   result and discussion are presented in Section 4. Finally, the
            history of heart disease [21-23] .                 conclusion of the research work is presented in Section 5.
              The  cardiac  dataset  obtained  from  the  clinic  is
            voluminous and contains many irrelevant and redundant   2. Related works
            attributes. These attributes of CVD risk factors may   This section presents the strengths and weaknesses of
            include  inactivity,  unhealthy  eating,  smoking,  diabetes,   various works conducted by other researchers, through
            age, and family history. Therefore, there is a need for   which we can identify the research gaps. There are different
            attribute selection to reduce data redundancy and accuracy   types of vascular heart diseases, including coronary
            improvement  using  machine  learning  techniques  to   heart disease, congestive heart failure, cardiomyopathy,
            predict the output from existing data . This emergence   congenital heart disease, arrhythmias, deep vein thrombosis
                                          [24]
            of machine learning algorithms or intelligent automated   and pulmonary embolism, and many others. Heart disease
            systems is widely applicable to several fields of studies   has been identified as one of the leading causes of death
            for the simplification and counteraction of their natural   globally. One of the reasons for heart disease-related deaths
            and artificial challenges as it usually yields optimum   is that the risk is not recognized at an earlier stage. Manually
            performance. Such emergent technology systems in health   calculating the chances of developing heart disease based
            care could be an expert system for different purposes, such   on risk factors is difficult, but machine learning methods


            Volume 1 Issue 1 (2024)                         43                        https://doi.org/10.36922/aih.1746
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