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Artificial Intelligence in Health                                Role of LLMs in improving patient experience



               (especially in the context of health communication   Transparency and trust are also concerns, particularly
               and when the patient has queries in between follow-  in “black box” AI systems where the efficacy may be
               ups),  ensure  that  the  patient  has  access  to  more   high but the decision-making process is unclear; here
               validated  and  accurate  health  information  (which   “explainability” is essential for physician trust, as the
               is  frequently  a challenge),  and increase patient   system can establish the reasoning behind a particular
               satisfaction. Especially when dealing with a particular   decision. Bias is a significant concern because the
               subspecialty, it is substantially simpler to curate and   data  on  which  the  model  is  trained  could  have
               verify information that will be accessible to the patient.   intrinsic gender, racial, ethnic, or other biases that
               For diverse patient populations, other advantages   the model has not considered and may reflect in the
               include multilingual abilities and cross-cultural   results. The other concerns, such as cybersecurity and
               adaptation. It may also relieve the existing nursing or   accountability for the outcomes, are self-evident.
               physician assistant team of the burden of addressing   •   Role of NLP: This has been extensively examined
               routine patient queries, allowing them to focus on   in 15 of the articles included in our review, with
               more urgent tasks. They may also contribute to the   a  particular  emphasis  on  the  efficacy  of  current
               alleviation of the burden on healthcare professionals,   NLP systems in a clinical context, for both general
               who are often confronted with an increasing amount   use and subspecialty use cases.  The scope of
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               of administrative and non-medical work, resulting in   applications was wide, including performing routine
               increased levels of burnout. 58-59                 cardiology  and predicting future opioid use,
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            •   Role  in  teleconsultations:  In Saudi Arabia,  a study   suicidal behavior, substance abuse, neuropsychiatric
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               by Alanzi  et al.  examined the perspectives of 54   disturbances, 48-50  and ICU readmission.  These are
               healthcare experts regarding the impact of ChatGPT   attractive propositions of a screening tool, especially
               on  teleconsultation.  They  specifically  examined  the   in settings where mental health services are limited or
               positive influence of ChatGPT on the following:    unavailable but are crucial for all patients. They could
               informational  support,  diagnostic  assistance,   act as a triage tool to ensure that high-priority patients
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               communications, enhancing efficiency, cost and     receive urgent referrals or care. One article  described
               time savings, personalizing patient care, multilingual   the construction of a clinical LLM, GatorTron,
               support, decision-making, documentation, assisting in   using >90 billion words of text, of which >82 billion
               medical research, and enhancing team collaboration.   were deidentified clinical text. This clinical text was
               The issues that were addressed included misdiagnosis   evaluated based on clinical concept extraction, medical
               and errors, issues in personalized care, limited medical   relation extraction, semantic textual similarity, natural
               context,  communication  challenges,  increased    language inference, and medical question answering.
               dependence on technology, ethical and legal issues,   Scaling up the volume and quality of the training data
               liability, and security and privacy. The conclusion that   considerably enhanced the output.
               the authors arrived at was that despite the enthusiasm   •   Screening for potential risks: An interesting use of
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               of most healthcare workers about the potential benefits   LLMs was demonstrated by Guevara  et al.,  who
               of the platform, using it in its present form led to more   demonstrated how they could be used to extract data
               questions than answers. Having a standardized, secure,   related to six specific social determinants of health
               optimized platform that capitalized on the capabilities   –  employment,  housing,  transport,  parental  status,
               of NLP and machine learning could resolve many     relationships, and  social  support  –  from narrative
               shortcomings in the current working system.        text in the electronic health records. This can assist
            •   Ethical challenges: In their review, Jeyaraman et al.    in  more  effective  screening  of  patients  who  may
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               succinctly summarize the ethical dilemmas associated   require additional assistance and are at higher risk of
               with the application of AI in healthcare. Privacy is a   complications to help potentially mitigate these in a
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               major concern with the use of big data in healthcare,   timely manner. Another study  attempted to predict
               which can manifest in diverse ways, including privacy   the 10-year cardiovascular risk in patients using
               breach, misuse of patient data, denial-of-service, and   LLMs, revealing comparable efficiency compared with
               ransomware  attacks in  life-threatening situations.   conventional nomograms and risk assessment models.
               Despite the existence of blueprints for ChatGPT to filter
               out patient-identifiable information and comply with   3.4. Contexts of use
               regulations such as the Health Insurance Portability   The articles included in our scoping review examined
               and Accountability Act and General Data Protection   the use of LLMs in several discrete settings. The first and
               Regulation,  the current systems are far from ideal.   most prevalent application was a patient-facing interface
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            Volume 2 Issue 2 (2025)                         5                                doi: 10.36922/aih.4808
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