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Artificial Intelligence in Health                                Role of LLMs in improving patient experience



            globe and the credible, objective results. However, these   currently evident. High-quality deidentified health care data
            articles have investigated different LLMs with minimal or   are needed from all populations to ensure adequate patient
            no customization, except for a single study that developed   representation in the resultant technology. Providers need
            an LLM from scratch. The increasing availability of medical   to collaborate with researchers to ensure this, not only from
            data-specific LLMs is expected to significantly address   a commercial perspective but also because high-quality,
            this heterogeneity. Much larger validation is required on a   relevant data are essential for the development of open-
            geographically, socially, and culturally diverse population   access or free tools. Researchers, providers, professional
            to ensure that these can be accepted for routine clinical   bodies and the industry need to work closely to comprehend
            use. 56-57  Given that any of these LLMs are regarded as   the scope of LLM-based tools, both at the population and
            decision-making aids or adjuncts, it is unclear which level   patient level, to collect the data and conduct the research
            of  stringency needs to  be  adopted for  their  validation   required to develop high-quality tools focused on patient-
            process. Consensus among large professional bodies and   specific outcomes that help enhance the quality of care
            organizations to collaborate on these solutions to ensure   delivery or patient experience. Technology can serve as a
            that the datasets on which they are trained and validated are   key force multiplier, particularly in regions where healthcare
            large and homogenous may be beneficial; this may also help   delivery and providers are scarce. Although recent regional
            ensure equitable and universal access to these technologies.  guidelines for the implementation of AI in healthcare have
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              A clear distinction exists between LLMs that are   been put in place,  there is still a significant absence of
            designed with a large population in mind for the purpose   consensus regarding the appropriate use and application of
            of screening or engagement and those designed to achieve   dozens of emerging tools and technologies in the healthcare
            a  clear,  objectively  actionable  outcome,  such  as  surgical   sector. Regional and international consensus is crucial to
            intervention, based on a comprehensive risk assessment.   ensure appropriate use. Finally, researcher collaboration
            The  latter  will  require  multiple  specific,  objective,  and   is the need of the hour; rather than performing numerous
            accurate parameters as inputs to facilitate inference,   independent small-scale validation of these tools, large trials
            while the former may permit a lower quantity and quality   need to be run on thousands of patients in a multicentric
            of data, as well as a lower specificity and sensitivity of   manner to assess them. With the progress in technology
            outcomes. When evaluating the appropriateness of these   and access, such tools are now feasible at a reasonable cost.
            tools for their ecosystems, practitioners must possess a   The buy-in of governments and payor systems is essential to
            comprehensive understanding of the training data and the   leverage this technology for the public interest.
            patient population under investigation. This is particularly   5. Conclusions
            true if it is a population-focused tool, such as a screening
            test, or a patient-centric tool, like a diagnostic test.  LLMs are becoming an increasingly common part of
              Another  significant  consideration  is  the  cost-benefit   daily life. Health systems and professionals worldwide
            ratio of these technologies and solutions. With spiraling   can capitalize on their influence by gaining a more
            healthcare costs around the world, it is now more crucial   comprehensive understanding of LLMs and utilizing
            than ever to be prudent with healthcare expenditure. The   their potential to develop a safe and suitable tool that can
            economic implications of incorporating LLMs into routine   enhance patient care and experience. Significant efforts
            practice depend considerably on how they are planned to   are needed to conduct large multicentric validations of
            be implemented. For an institutional LLM that is a white-  these tools before they are routinely applied in clinical
            labeled, optimized version of  a commercially  available   practice. It is imperative that providers should gain a
            product, the cost addition to the patient may be negligible,   better understanding of these technologies and tools in a
            whereas a subscription to a technology product linked to   much more comprehensive manner to ensure that patients
            the electronic medical record system may be too expensive   benefit from them in a demonstrable and meaningful way.
            or inaccessible for most. Additional research is required to   Acknowledgments
            better comprehend the needs of the local patient, provider,
            and healthcare system, for whom these factors can vary   None.
            widely. Notably, none of these articles utilized tools that
            are fully validated or approved for immediate clinical use,   Funding
            reinforcing the fact that this technology, despite its high   None.
            potential in healthcare, remains a work in progress.
              The next steps to ensure that these tools are utilized in   Conflict of interest
            an appropriate, acceptable, and patient-centric manner are   The authors declare they have no competing interests.


            Volume 2 Issue 2 (2025)                         7                                doi: 10.36922/aih.4808
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