Page 15 - AN-2-1
P. 15
Advanced Neurology The AIS structure and function
dendrites convey privileged synaptic input in hippocampal 50. Wimmer VC, Reid CA, So EY, et al., 2010, Axon initial
neurons. Neuron, 83: 1418–1430. segment dysfunction in epilepsy. J Physiol, 588: 1829–1840.
https://doi.org/10.1016/j.neuron.2014.08.013 https://doi.org/10.1113/jphysiol.2010.188417
39. Triarhou LC, 2014, Axons emanating from dendrites: 51. Sobotzik JM, Sie JM, Politi C, et al., 2009, AnkyrinG is
Phylogenetic repercussions with Cajalian hues. Front required to maintain axo-dendritic polarity in vivo. Proc
Neuroanat, 8: 133. Natl Acad Sci U S A, 106: 17564–17569.
https://doi.org/10.3389/fnana.2014.00133 https://doi.org/10.1073/pnas.0909267106
40. Chen ZY, Peng L, Zhao M, et al., 2022, Differences in action 52. Eichel K, Shen K, 2022, The function of the axon initial
potential propagation speed and axon initial segment segment in neuronal polarity. Dev Biol, 489: 47–54.
plasticity between neurons from Sprague-Dawley rats and
C57BL/6 mice. Zool Res, 43: 615–633. https://doi.org/10.1016/j.ydbio.2022.05.016
https://doi.org/10.24272/j.issn.2095-8137.2022.121 53. Song AH, Wang D, Chen G, et al., 2009, A selective filter
for cytoplasmic transport at the axon initial segment. Cell,
41. Araki T, Otani T, 1955, Response of single motoneurons 136: 1148–1160.
to direct stimulation in toad’s spinal cord. J Neurophysiol,
18: 472–485. https://doi.org/10.1016/j.cell.2009.01.016
https://doi.org/10.1152/jn.1955.18.5.472 54. Sun X, Wu Y, Gu M, et al., 2014, Selective filtering defect
at the axon initial segment in Alzheimer’s disease mouse
42. Coombs JS, Eccles JC, Fatt P, 1955, The electrical properties models. Proc Natl Acad Sci U S A, 111: 14271–14276.
of the motoneurone membrane. J Physiol, 130: 291–325.
https://doi.org/10.1073/pnas.1411837111
https://doi.org/10.1113/jphysiol.1955.sp005411
55. Petersen JD, Kaech S, Banker G, 2014, Selective microtubule-
43. Fuortes MG, Frank K, Becker MC, 1957, Steps in the based transport of dendritic membrane proteins arises in
production of motoneuron spikes. J Gen Physiol, 40: 735–752.
concert with axon specification. J Neurosci, 34: 4135–4147.
https://doi.org/10.1085/jgp.40.5.735
https://doi.org/10.1523/JNEUROSCI.3779-13.2014
44. Catterall WA, 1981, Localization of sodium channels in 56. Al-Bassam S, Xu M, Wandless TJ, et al., 2012, Differential
cultured neural cells. J Neurosci, 1: 777–783.
trafficking of transport vesicles contributes to the localization
https://doi.org/10.1523/JNEUROSCI.01-07-00777.1981 of dendritic proteins. Cell Rep, 2: 89–100.
45. Foust A, Popovic M, Zecevic D, et al., 2010, Action potentials https://doi.org/10.1016/j.celrep.2012.05.018
initiate in the axon initial segment and propagate through
axon collaterals reliably in cerebellar Purkinje neurons. 57. Burack MA, Silverman MA, Banker G, 2000, The role of
J Neurosci, 30: 6891–6902. selective transport in neuronal protein sorting. Neuron,
26: 465–472.
https://doi.org/10.1523/JNEUROSCI.0552-10.2010
https://doi.org/10.1016/s0896-6273(00)81178-2
46. Khaliq ZM, Raman IM, 2006, Relative contributions of
axonal and somatic Na channels to action potential initiation 58. Farias GG, Guardia CM, Britt DJ, et al., 2015, Sorting of
in cerebellar Purkinje neurons. J Neurosci, 26: 1935–1944. dendritic and axonal vesicles at the pre-axonal exclusion
zone. Cell Rep, 13: 1221–1232.
https://doi.org/10.1523/JNEUROSCI.4664-05.2006
https://doi.org/10.1016/j.celrep.2015.09.074
47. Liao Y, Anttonen AK, Liukkonen E, et al., 2010, SCN2A
mutation associated with neonatal epilepsy, late-onset 59. Janssen AF, Tas RP, van Bergeijk P, et al., 2017, Myosin-V
episodic ataxia, myoclonus, and pain. Neurology, induces cargo immobilization and clustering at the axon
75: 1454–1458. initial segment. Front Cell Neurosci, 11: 260.
https://doi.org/10.1212/WNL.0b013e3181f8812e https://doi.org/10.3389/fncel.2017.00260
48. Schafer DP, Jha S, Liu FD, et al., 2009, Disruption of the 60. Grubb MS, Burrone J, 2010, Activity-dependent relocation
axon initial segment cytoskeleton is a new mechanism for of the axon initial segment fine-tunes neuronal excitability.
neuronal injury. J Neurosci, 29: 13242–13254. Nature, 465: 1070–1074.
https://doi.org/10.1523/JNEUROSCI.3376-09.2009 https://doi.org/10.1038/nature09160
49. Wimmer VC, Reid CA, Mitchell S, et al., 2010, Axon initial 61. Kuba H, Oichi Y, Ohmori H, 2010, Presynaptic activity
segment dysfunction in a mouse model of genetic epilepsy regulates Na(+) channel distribution at the axon initial
with febrile seizures plus. J Clin Invest, 120: 2661–2671. segment. Nature, 465: 1075–1078.
https://doi.org/10.1172/JCI42219 https://doi.org/10.1038/nature09087
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