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Advanced Neurology Choreoathetosis with contralateral substantia nigra infarction

Table 2. Previous reports of substantia nigra infarction.
Literature Sex Age Clinical symptoms/manifestations Medical history
Robles [6] Female 68 Bilateral lower limb resting tremor Hypertension and dyslipidemia
Ohta and Obara [7] Male 61 Bradykinesia, cogwheel rigidity, and resting tremor Hypertension
of the left hand
Hunter et al. [8] Male 62 Right-sided parkinsonism characterized by rigidity Hypertension
and flexion
Kim and You [9] Female 71 Akinetic mutism and decreased speech, movement, Hypertension, diabetes, and old
and emotional reactions cerebral infarction
Orta Daniel and Ulises [10] Female 45 Bradykinesia, hypomimia, hypophonia, dysarthria, Systemic lupus erythematosus
hypokinesia, rigidity in the neck and all four limbs,
resting tremor in the left arm, and festinating gait
Gonzalez-Alegre [11] Male 18 Parkinsonian tremor in the contralateral foot Subarachnoid
Hemorrhage
Akyol, Akyildiz , and Tataroglu [12] Male 80 Bradykinesia, resting tremor of the left hand, and –
tremor of the lower limbs in an upright position,
particularly in the left leg
Caparros-Lefebvre et al. [13] Male 70 Biballism or paraballism Hypertension
McKee et al. [14] Male 83 Visual hallucinations, disordered sleep, and mild Myocardial infarction with atrial
cognitive impairment fibrillation

4. Conclusion Weifang Medical University approved the study. The
approval number is wyfy-2022-ky-182.
We present a case of choreoathetosis as the first manifestation
of an ischemic lesion involving the contralateral SN. In our Consent for publication
reported case, it is of concern that the localization of lesion
shown by MRI, DWI, and MRA is associated with the sudden Written informed consent was obtained from the patient
specific clinical symptom. This enlightening case suggests that for publication of this case report and any accompanying
clinicians should consider the possibility of ischemic stroke in images.
the contralateral nigrostriatal pathway in patients presenting Availability of data
with sudden and rapidly progressive dance-like movements.
The datasets used and/or analyzed during the present study
Acknowledgments are available from the corresponding author on reasonable
None. request.
Funding References

Supported by Yuandu scholars and Weifang Key Laboratory. 1. Defebvre L, Krystkowiak P, 2016, Movement disorders and
stroke. Rev Neurol (Paris), 172: 483–487.
Conflict of interest https://doi.org/10.1016/j.neurol.2016.07.006

The authors declare they have no competing interests. 2. Alarcón F, Zijlmans JC, Dueñas G, et al., 2004, Post-stroke
movement disorders: Report of 56 patients. J Neurol
Author contributions Neurosurg Psychiatry, 75: 1568–1574.
Conceptualization: Yanqiang Wang https://doi.org/10.1136/jnnp.2003.011874
Investigation: Mengxin Li and Xiaojun Zhang 3. Tater P, Pandey S, 2021, Post-stroke movement disorders:
Supervision: Yanqiang Wang Clinical spectrum, pathogenesis, and management. Neurol
Writing – original draft: Mengxin Li and Yanqiang Wang India, 69: 272–283.
Writing – review & editing: Mengxin Li and Yanqiang Wang
https://doi.org/10.4103/0028-3886.314574
Ethics approval and consent to participate 4. Sonne J, Reddy V, Beato MR, 2022, Neuroanatomy,

Written consent was obtained from the patient. The substantia nigra. StatPearls Publishing, Treasure Island.
Medical Ethics Committee of the Affiliated Hospital of 5. Morgan JC, Sethi KD, 2003, Midbrain infarct with

Volume 2 Issue 1 (2023) 5 https://doi.org/10.36922/an.v2i1.141