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Advanced Neurology                                        MNS in patients with anxiety and depressive symptoms


















            Figure 1. Experimental design: The baseline data were recorded immediately before the new series of tasks. The subject sat opposite the demonstrator.
            The first observation task started immediately after baseline, and the subject observed the demonstrator clenching their hand. The subject then performed
            the movement (execution) and imagined themselves performing the movement (imagination). The last task was a joint execution—the subject and
            demonstrator had to clench their hands synchronously while watching each other.

            A                                                B

















            C                                                D


















            Figure 2. Alpha 1 (A), alpha 2 (B), and beta1 (C) relative normalized power density (baseline = 0) in frontal, central, and occipital brain areas during mirror
            tasks in patients and the control group. (D) Activation maps, created using the sLORETA separately for both the patient and control groups, were compared
            in three bands during mirror tasks against the baseline. Higher activation corresponds to the brighter yellow areas.

            desynchronization occurs. Notably, in the control group,   performance of various active tasks separately in the patient
            rhythm suppression in all four “mirror” tasks occurred   and control groups. Because the MNS is activated during
            strictly in the alpha2 range and only in the central regions,   observation, imagination, and execution, we used data
            as expected.                                       from all four samples. In this way, we found the putative
                                                               sources of rhythm activity that worked simultaneously in
            3.2. Data from sLORETA                             all four tasks compared to the baseline.

            Using  the  sLORETA  source localization method, we   Activity distribution maps are shown in  Figure  2D.
            visualized maps of brain activation regions during the   More activation corresponds to the brighter yellow areas.


            Volume 3 Issue 1 (2024)                         6                         https://doi.org/10.36922/an.2009
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