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Advanced Neurology                                              Shuntogram technique in programmable valves




            Table 1. Summary of shuntogram technique characteristics
            in 25 publications
            Parameter                                Value
            No. of studies (N)                       25
            Series                                   12 (48)
            Case studies                             11 (44)
            Other                                    2 (8)
            Age
             Adult                                   7 (28)
             Pediatrics                              12 (48)
             Both                                    4 (16)
             Neither                                 2 (8)
            Indication
             Clinical presentation                   13 (52)
             Imaging                                 9 (36)    Figure 3. Positioning of the X-ray for oblique view in the sagittal plane for
            Positioning                                        ventriculoperitoneal shunt series
             Supine                                  6 (24)
             Recumbent                               2 (8)     novel scintillation camera (fluoroscopy), capturing images
            Skin prep                                          at 10, 20, and 60 min, with additional imaging in an erect
             Iodine-based cleanser                   5 (20)    position if migration was not observed after pumping.
             Chlorhexidine and alcohol               2 (8)     A negative result was verified if, after 6 months, no revision
             Asepsis                                 4 (16)    was necessary.
            Time                                                 Mirfakhraee et al.  examined the effect of positioning
                                                                                12
             <10 min                                 4 (16)    using a supine position using the head in a lateral
             15 – 45 min                             4 (16)    orientation. Their timeline for “normal” distal flow was
             >45 min                                 5 (20)    narrow, defined as 3 to 9 min; however, only patients with
             Pumped manually                         4 (16)    hydrocephalus on presentation were included in the study.
                                                                                             13
            Radio contrast                                     A few years later, Sweeney and Thomas  performed a study
             Variants of  Tc                         13 (52)   on 250 shuntograms, enrolling patients with irritability,
                     99m
             Metrizamide                             2 (8)     vomiting, headaches, or pyrexia. Preparation involved
             Iopamidol                               2 (8)     shaving  the  scalp,  employing  an  aseptic  technique,  and
                                                               using a 23-gauge butterfly needle for CSF aspiration.
             Iohexol                                 3 (12)    Iopamidol was injected, with contrast distal to the valve
             111 In-DTPA                             3 (12)    observed and manual pumping applied as needed to assist
             Meglumine                               1 (4)     distal flow. This approach led to 16 false interpretations,
             Diatrizoate                             1 (4)     with nine cases requiring shunt revision. These two studies
             Unspecified                             5 (20)    did not specify how contrast progression was monitored,
            Needle gauge                                       and definitions of shunt failure were inconsistently
             23                                      3 (12)    applied.
             25                                      7 (28)      By 1991, Benzel et al.  maintained a supine position
                                                                                   16
            Injectate amount                                   for patients 1  h before the procedure, although contrast
             <1 mL                                   1 (4)     agents remained variable across institutions.  They noted
                                                                                                  9,13
             3 ml                                    1 (4)     that lowering shunt drainage pressure when the flow was
             Changed position                        2 (8)     initially stalled allowed 18 of 22 shunts to resume flow after
             Sensitivity (37.5 – 92.6%)              3 (12)    surgically placing a lower-pressure valve.  Pumping was
                                                                                                16
             Specificity (59.5 – 100%)               3 (12)    frequently employed across studies to stimulate flow. 8,16,18
             False negative (8 – 25%)                5 (20)    However, Piatt’s 27,28  studies in 1992 and 1996 highlighted
             False positive (0 – 100%)               4 (16)    the limitations of the pumping test, reporting a sensitivity
            Note: Values are expressed as n (%) unless otherwise specified.   of 50%, specificity of 64%, and a likelihood ratio of 1.39.
            Additional reference citations can be found in Table S1.  It was concluded that the pumping test alone was neither

            Volume 3 Issue 4 (2024)                         5                                doi: 10.36922/an.4180
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