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Advanced Neurology                                                       Cognition in children with mild TBI
























                                    Figure 2. Eligibility and exclusion criteria for the monocentric cohort study

                                                               Table 2. Clinical and demographic characteristics of the 15
                                                               children who were admitted for mTBI mild‑to‑moderate TBI
                                                               Characteristics                         n=15
                                                               Age at the time of TBI, years, median (IQR)   9 (5.5 – 14)
                                                               Sex, n
                                                                Males                                 11
                                                                Females                               4
                                                               Mechanism of injury, n
                                                                High speed (motor vehicle accident/bicycle collision)   10
                                                                Fall from a height                    4
                                                                Head struck by a heavy object (unintentional)   1
            Figure 3. Neuroradiological findings obtained at the time of diagnosis (T0)  Impact site, n
                                                                Occipital                             2
              Overall, results obtained at T2 were borderline or   Temporal                           2
                                                                                                      2
                                                                Frontal
            slightly below the expected level. However, a comparison   Multiple                       4
            of the T2 data with reference values (one-sample  t-test)   Unknown                       4
            demonstrated significantly lower scores in the memory and   GCS at time of first evaluation, median (IQR)   14 (12–15)
            learning domain, sensorimotor functions (finger tapping),   Symptoms, n
            social perception (affect recognition), and visuospatial   Loss of consciousness          7
            abilities (design copying) (Table 4).               Headache                              5
                                                                Vomiting                              5
            3.2.4. Cognitive assessment                         Post-traumatic amnesia                5
                                                                Drowsiness                            5
            Twelve children were assessed using the WISC-IV scale at   Altered neurological examination, n   4
            T1 and T2. However, two children were evaluated using
            the WPPSI-III according to age. The FSIQ results of the   Admission, n                    10
                                                                General pediatric ward
            children were not significantly different between T1 and   ICU                            3
            T2  (106.1 ± 6.9  vs. 103.5 ± 10.7;  P  = 0.25) (Figure  4).   Emergency department (short-stay observation unit)   2
            Furthermore,  the T2  results  were  not significantly   Abbreviations: TBI: Traumatic brain injury; IQR: Interquartile range;
            different compared with the reference values (one-sample   GCS: Glasgow coma scale; ICU: Intensive care unit.
            t-test; P = 0.5).
                                                               T1 (Table 5). The median t-scores for total (P = 0.898),
            3.2.5. Emotional and behavioral assessment         internalizing (P = 0.156), and externalizing (P = 0.953)
            The CBCL data for children aged 6 – 18  years were   behavioral issues were not significantly different between
            obtained from the parents  of eight  children at T0 and   T0 and T1.





            Volume 3 Issue 4 (2024)                         14                               doi: 10.36922/an.3886
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