Page 67 - AN-3-4
P. 67

Advanced Neurology                                                       Cognition in children with mild TBI




            Table 5. Comparison of the child behavior checklist data collected from the parents of children with traumatic brain injury at T0
            and T1
            Patient no.                     T0 (n=8)                                  T1 (n=8)
                           Internalizing issues  Externalizing issues  Total score  Internalizing issues  Externalizing issues  Total score
            1                    34             40            27           40              40           34
            2                    61 a           48            57           46              47           52
            3                    41             39            38           41              33           42
            4                    50             53            54           58              59           61 a
            5                    58             48            53           47              46           49
            6                    65b            46            52           44              40           34
            7                    58             43            50           44              46           46
            8                    44             40            40           40              43           42
            Median (IQR)     54 (43.2 – 58.7)  44.5 (40 – 48)  51 (39.5 – 53.2)  44 (40.7 – 46.2)  44.5 (40 – 46.2)  44 (40 – 49.2)
            P-value* (T0 vs. T1)  0.156        0.953         0.898
            Notes:  Risk score category;  Clinical symptoms category; Statistical analysis was performed using the two-tailed t-test. *P<0.05. T0: Baseline; T1: 3 – 6
                              b
                 a
            months after the event.
            Abbreviation: IQR: Interquartile range.
            Table 6. MRI and cognitive evaluation of children with traumatic brain injury performed during the follow‑up period
            Patient Baseline head CT     MRI (1 – 3 months after injury)  MRI (4 – 6 months after   Cognitive outcome (up to 24
                                                                  injury)            months later)
            1     Left parietal          Regular evolution of cerebral   -           No deficits
                  fracture+fronto-orbital cerebral   contusions
                  contusions (contrecoup)
            2     Right fronto-temporal extradural  -             Regular            Deficits in attention, executive
                  and subdural hematoma                           evolution+non-specific   functions, memory, and motor
                                                                  hyperintense spots in   planning
                                                                  bilateral semioval centers
            3     Normal                 -                        Normal             No deficits
            4     Normal                 -                        -                  No deficits
            5     Normal                 -                        Normal             No deficits
            6     Minimal left frontal contusion  -               Regular evolution   No deficits
            7     Right temporo-parietal fracture  -              Normal             Deficits in language and verbal
                                                                                     memory
            8     Left fronto-temporal fracture and  Bilateral fronto-basal and   Regular evolution   No deficits
                  cerebral contusion     temporo-polar contusions
            9     Left fronto-basal cerebral   -                  Regular evolution   Deficits in attention, memory, and
                  contusions                                      (hemosiderin depositions)   visual perception abilities
            10    Right fronto-parietal subdural   Multiple DAI (vermian, occipital,   Regular evolution+reduced  Deficits in memory as well as
                  hematoma+DAI           pontine, fornix, and vertex)  CC thickness  visuospatial and construction abilities
            11    Cerebral contusions (contrecoup)  Multiple cerebral contusions   Regular evolution   Deficits in attention, memory, and
                  on the tentorium       (contrecoup): bilateral temporo-mesial      visual perception abilities
                                         (righ t>left), temporal lobe, CC
                                         (splenium), and left frontal involvement
            12    Right fronto-orbital fracture and  -            Regular evolution   Deficits in memory for faces
                  subdural hematoma
            13    Basal skull fracture   -                        -                  Deficits in attention and executive
                                                                                     functions and verbal memory
            14    Normal                 -                        -                  No deficits
            15    Normal                 -                        -                  No deficits
            Abbreviations: CC: Corpus callosum; CT: Computed tomography; DAI: Diffuse axonal injury; MRI: Magnetic resonance imaging.


            Volume 3 Issue 4 (2024)                         16                               doi: 10.36922/an.3886
   62   63   64   65   66   67   68   69   70   71   72