Page 42 - AN-4-1

Advanced Neurology Ferroptosis in neonatal HIBI

19. Kaminogo M, Suyama K, Ichikura A, Onizuka M, Shibata S. An iron-dependent form of nonapoptotic cell death. Cell.
Anoxic depolarization determines ischemic brain injury. 2012;149(5):1060-1072.
Neurol Res. 1998;20(4):343-348.
doi: 10.1016/j.cell.2012.03.042
doi: 10.1080/01616412.1998.11740529
32. Johnson DS, Chen YH. Ras family of small GTPases
20. Lipton SA, Rosenberg PA. Excitatory amino acids as a final in immunity and inflammation. Curr Opin Pharmacol.
common pathway for neurologic disorders. N Engl J Med. 2012;12(4):458-463.
1994;330(9):613-622.
doi: 10.1016/j.coph.2012.02.003
doi: 10.1056/NEJM199403033300907
33. Dolma S, Lessnick SL, Hahn WC, Stockwell BR.
21. Tremblay E, Roisin MP, Represa A, Charriaut-Marlangue C, Identification of genotype-selective antitumor agents using
Ben-Ari Y. Transient increased density of NMDA binding synthetic lethal chemical screening in engineered human
sites in the developing rat hippocampus. Brain Res. tumor cells. Cancer Cell. 2003;3(3):285-296.
1988;461(2):393-396.
doi: 10.1016/s1535-6108(03)00050-3
doi: 10.1016/0006-8993(88)90275-2
34. Yagoda N, von Rechenberg M, Zaganjor E, et al. RAS-RAF-
22. Represa A, Tremblay E, Ben-Ari Y. Transient increase MEK-dependent oxidative cell death involving voltage-
of NMDA-binding sites in human hippocampus during dependent anion channels. Nature. 2007;447(7146):864-868.
development. Neurosci Lett. 1989;99(1-2):61-66.
doi: 10.1038/nature05859
doi: 10.1016/0304-3940(89)90265-6
35. Yang WS, Stockwell BR. Synthetic lethal screening identifies
23. Liu F, McCullough LD. Inflammatory responses in compounds activating iron-dependent, nonapoptotic cell
hypoxic ischemic encephalopathy. Acta Pharmacol Sin. death in oncogenic-RAS-harboring cancer cells. Chem Biol.
2013;34(9):1121-1130. 2008;15(3):234-245.
doi: 10.1038/aps.2013.89 doi: 10.1016/j.chembiol.2008.02.010
24. Lacerte M, Hays Shapshak A, Mesfin FB. Hypoxic Brain 36. Deng L, He S, Guo N, Tian W, Zhang W, Luo L. Molecular
Injury. StatPearls Publishing; 2023. Available from: https:// mechanisms of ferroptosis and relevance to inflammation.
www.ncbi.nlm.nih.gov/books/NBK537310 [Last accessed Inflamm Res. 2023;72(2):281-299.
on 2024 Oct 10].
doi: 10.1007/s00011-022-01672-1
25. Elmore S. Apoptosis: A review of programmed cell death. 37. Liu Y, Gu W. p53 in ferroptosis regulation: The new weapon
Toxicol Pathol. 2007;35(4):495-516.
for the old guardian. Cell Death Differ. 2022;29(5):895-910.
doi: 10.1080/01926230701320337
doi: 10.1038/s41418-022-00943-y
26. Lipton P. Ischemic cell death in brain neurons. Physiol Rev. 38. Zheng H, Jiang L, Tsuduki T, Conrad M, Toyokuni S.
1999;79(4):1431-1568.
Embryonal erythropoiesis and aging exploit ferroptosis.
doi: 10.1152/physrev.1999.79.4.1431 Redox Biol. 2021;48:102175.
27. Tang S, Gao P, Chen H, Zhou X, Ou Y, He Y. The role of iron, doi: 10.1016/j.redox.2021.102175
its metabolism and ferroptosis in traumatic brain injury. 39. Cai W, Liu L, Shi X, et al. Alox15/15-HpETE
Front Cell Neurosci. 2020;14:590789.
aggravates myocardial ischemia-reperfusion injury
doi: 10.3389/fncel.2020.590789 by promoting cardiomyocyte ferroptosis. Circulation.
2023;147(19):1444-1460.
28. Khalid N, Azimpouran M. Necrosis. StatPearls Publishing;
2023. Available from: https://www.ncbi.nlm.nih.gov/books/ doi: 10.1161/CIRCULATIONAHA.122.060257
NBK557627 [Last accessed on 2024 Oct 10].
40. Chen L, Hambright WS, Na R, Ran Q. Ablation of the
29. Wu L, Chang E, Zhao H, Ma D. Regulated cell death in ferroptosis inhibitor glutathione peroxidase 4 in neurons
hypoxic-ischaemic encephalopathy: Recent development and results in rapid motor neuron degeneration and paralysis.
mechanistic overview. Cell Death Discov. 2024;10(1):277-216. J Biol Chem. 2015;290(47):28097-28106.
doi: 10.1038/s41420-024-02014-2 doi: 10.1074/jbc.M115.680090
30. Yang Z, Klionsky DJ. An overview of the molecular 41. Friedmann Angeli JP, Schneider M, Proneth B, et al.
mechanism of autophagy. Curr Top Microbiol Immunol. Inactivation of the ferroptosis regulator Gpx4 triggers acute
2009;335:1-32. renal failure in mice. Nat Cell Biol. 2014;16(12):1180-1191.
doi: 10.1007/978-3-642-00302-8_1 doi: 10.1038/ncb3064
31. Dixon SJ, Lemberg KM, Lamprecht MR, et al. Ferroptosis: 42. Li Y, Feng D, Wang Z, et al. Ischemia-induced ACSL4

Volume 4 Issue 1 (2025) 36 doi: 10.36922/an.4575