Page 61 - AN-4-4
P. 61
Advanced Neurology Covert cerebral small vessel disease
markers of vascular brain injury: A systematic review and and methods: The cuban brain mapping project. Clin EEG
meta-analysis. JAMA Neurol. 2019;76(1):81-94. Neurosci. 2011;42(3):149-159.
doi: 10.1001/jamaneurol.2018.3122 doi: 10.1177/155005941104200303
7. Das AS, Regenhardt RW, Vernooij MW, Blacker D, 17. Huang Y, Wang S, Cai C, et al. Retinal vascular density as a
Charidimou A, Viswanathan A. Asymptomatic cerebral potential biomarker of diabetic cerebral small vessel disease.
small vessel disease: Insights from population-based studies. Diabetes Obes Metab. 2024;26(5):1789-1798.
J Stroke. 2019;21(2):121-138. doi: 10.1111/dom.15492
doi: 10.5853/jos.2018.03608
18. Hernández-Díaz Z, Peña-Sánchez M, González-Quevedo A,
8. Wang Z, Chen Q, Chen J, Yang N, Zheng K. Risk factors of et al. Cerebral small vessel disease associated with subclinical
cerebral small vessel disease: A systematic review and meta- vascular damage indicators in asymptomatic hypertensive
analysis. Medicine (Baltimore). 2021;100(51):e28229. patients. Behav Sci (Basel). 2019;9(9):91.
doi: 10.1097/MD.0000000000028229 doi: 10.3390/bs9090091
9. Yi F, Jacob MA, Verhoeven JI, et al. Baseline and 19. Del Brutto V, Ortiz J, Del Brutto O, Mera R, Zambrano M,
longitudinal MRI markers associated with 16-year mortality Biller J. Total cerebral small vessel disease score and
in patients with cerebral small vessel disease. Neurology. cognitive performance in community-dwelling older adults.
2024;103:e209701. Results from the atahualpa project. Int J Geriatr Psychiatry.
2018;33(2):325-331.
doi: 10.1212/WNL.0000000000209701
doi: 10.1002/gps.4747
10. Abraham H, Wolfson L, Moscufo N, Guttmann CR,
Kaplan RF, White WB. Cardiovascular risk factors and small 20. González-Quevedo A, González García S, Peña Sánchez M,
vessel disease of the brain: Blood pressure, white matter et al. Detecting asymptomatic cerebral small vessel
lesions, and functional decline in older persons. J Cereb disease. Brain specific proteins as surrogate biomarkers.
Blood Flow Metab. 2016;36(1):132-142. In: González-Quevedo A, Dambinova SA, Bettermann K,
editors. Understanding and Treating Cerebral Small Vessel
doi: 10.1038/jcbfm.2015.121
Disease. New York, USA: Nova Science Publishers; 2021.
11. Zhou Z, You S, Sakamoto Y, et al. Covert cerebrovascular p231-266.
changes in people with heart disease: A systematic review
and meta-analysis. Neurology. 2024;102(8):e209204. 21. Huang Y, Wang Z, Huang ZX, Liu Z. Biomarkers and
the outcomes of ischemic stroke. Front Mol Neurosci.
doi: 10.1212/WNL.0000000000209204 2023;16:1171101.
12. Wardlaw JM, Debette S, Jokinen H, et al. ESO Guideline doi: 10.3389/fnmol.2023.1171101
on covert cerebral small vessel disease. Eur Stroke J. 22. Papa L, McKinley WI, Valadka AB, et al. Diagnostic
2021;6(2):CXI-CLXII.
performance of GFAP, UCH-L1, and MAP-2 within 30 and
doi: 10.1177/23969873211012132 60 minutes of traumatic brain injury. JAMA Netw Open.
2024;7(9):e2431115.
13. Smith EE, Saposnik G, Biessels GJ, et al. Prevention of stroke
in patients with silent cerebrovascular disease: A scientific doi: 10.1001/jamanetworkopen.2024.31115
statement for health care professionals from the American 23. Wen Q, Thukral R, Yang HC, et al. Longitudinal associations
Heart Association/American Stroke Association. Stroke. between blood biomarkers and white matter MRI in sport-
2017;48(2):e44-e71.
related concussion: A study of the NCAA-DoD CARE
doi: 10.1161/STR.0000000000000116 consortium. Neurology. 2023;101(2):e189-e201.
14. Tully P, Yano Y, Launer L, et al. Association between blood doi: 10.1212/WNL.0000000000207389
pressure variability and cerebral small-vessel disease: A 24. Butkova TV, Malsagova KA, Nakhod VI, et al. Candidate
systematic review and meta-analysis. J Am Heart Assoc. molecular biomarkers of traumatic brain injury: A
2020;9:e013841.
systematic review. Biomolecules. 2024;14(10):1283.
doi: 10.1161/JAHA.119.013841
doi: 10.3390/biom14101283
15. Wu LY, Chai YL, Cheah IK, et al. Blood-based biomarkers of 25. Hoiland RL, Rikhraj KJK, Thiara S, et al. Neurologic
cerebral small vessel disease. Ageing Res Rev. 2024;95:102247.
prognostication after cardiac arrest using brain biomarkers:
doi: 10.1016/j.arr.2024.102247 A systematic review and meta-analysis. JAMA Neurol.
2022;79(4):390-398.
16. Hernández-González G, Bringas-Vega M, Galán-García L,
et al. Multimodal quantitative neuroimaging databases doi: 10.1001/jamaneurol.2021.5598
Volume 4 Issue 4 (2025) 55 doi: 10.36922/an.4841

