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Advances in Radiotherapy
            & Nuclear Medicine                                                CCRT plus nimotuzumab for cervical cancer




            Table 2. Acute toxicities (CTCAE 4.0)
                               Grade 0 (%)   Grade 1 (%)  Grade 2 (%)   Grade 3 (%)   Grade 4 (%)   Grade 5 (%)
            WBC                  2 (5.9)       1 (2.9)      14 (41.2)    17 (50.0)       0 (0)         0 (0)
            Net                 5 (14.7)       3 (8.8)      20 (58.8)     6 (17.6)       0 (0)         0 (0)
            PLT                 15 (44.1)     7 (20.6)      5 (14.7)      7 (20.6)       0 (0)         0 (0)
            Anemia              10 (29.4)     6 (17.6)      15 (44.1)     3 (8.8)        0 (0)         0 (0)
            Nausea              8 (23.5)      15 (44.1)     8 (23.5)      3 (8.8)        0 (0)         0 (0)
            Vomit               23 (67.6)     8 (23.5)      2 (5.9)       1 (2.9)        0 (0)         0 (0)
            Diarrhea            15 (44.1)     16 (47.1)     3 (8.8)        0 (0)         0 (0)         0 (0)
            Anorectal mucositis  12 (35.3)    16 (47.1)     6 (17.6)       0 (0)         0 (0)         0 (0)
            Urinary system      26 (76.5)     7 (20.6)      1 (2.9)        0 (0)         0 (0)         0 (0)
            Vaginal mucositis   29 (85.3)      2 (5.9)      2 (5.9)       1 (2.9)        0 (0)         0 (0)
            Skin ulcer          23 (67.6)     10 (29.4)     1 (2.9)        0 (0)         0 (0)         0 (0)
            Rash                33 (97.1)      1 (2.9)       0 (0)         0 (0)         0 (0)         0 (0)
            Paresthesia         33 (97.1)      0 (0)        1 (2.9)        0 (0)         0 (0)         0 (0)
            Liver dysfunction   33 (97.1)      1 (2.9)       0 (0)         0 (0)         0 (0)         0 (0)
            Abrreviations: PLT: Platelet; WBC: White blood cell; CTCAE: Common terminology criteria for adverse events.


            Table 3. Late toxicities (CTCAE 4.0)

            Toxicities (n [%])    Grade 1 (%)      Grade 2 (%)     Grade 3 (%)      Grade 4 (%)      Grade 5 (%)
            Intestinal fistula        0               0                0              1 (2.9)           0
            Intestinal obstruction    0               0              1 (2.9)            0               0
            Bloody stool              0              2 (5.9)           0                0               0
            Fecal incontinence      1 (2.9)           0                0                0               0
            Hematuria               3 (8.8)          1 (2.9)           0                0               0
            Vaginal adhesions       3 (8.8)           0                0                0               0
            Paresthesia             3 (8.8)         4 (11.8)           0                0               0
            Abbreviation: CTCAE: Common terminology criteria for adverse events.

























            Figure 1. Disease-free survival of patients.       Figure 2. Local progression-free survival of patients.




            Volume 1 Issue 1 (2023)                         4                       https://doi.org/10.36922/arnm.0408
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