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Advances in Radiotherapy
            & Nuclear Medicine                                   Integrating pet nutrition with radiotherapy and nuclear medicine



              Radiotherapy, a key cancer treatment in both human   healthy tissue. The efficacy of radiotherapy relies on its
            and veterinary medicine, utilizes ionizing radiation to   ability to administer therapeutic levels of radiation while
            target and destroy cancer cells while sparing surrounding   minimizing harm to healthy tissues. Prior studies have
            healthy tissue. However, the effectiveness of radiotherapy   shown  that nutrition  plays  a crucial role  in  enhancing
            depends on delivering therapeutic doses of radiation while   patient health and resilience against radiation effects.
            minimizing damage to normal tissues. In this context, the   Consuming nutritious food boosts the immune system,
            importance of nutrition in optimizing patient health and   improves tissue healing, and reduces treatment-related
            resilience is paramount.  High-quality nutrition supports   side effects, which helps patients adhere to their treatment
                               4
            immune  function,  enhances  tissue  repair  mechanisms,   plans and achieve better results. 7,8
            and mitigates treatment-associated side effects, thereby   Research has emphasized the significance of nutritional
            facilitating adherence to treatment protocols and   management for dogs undergoing radiation therapy.  One
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            improving treatment outcomes. Similarly, nuclear medicine   study reported that proper dietary management resulted
            techniques such as positron emission tomography (PET)   in better outcomes in terms of weight maintenance and
            and targeted radionuclide therapies offer valuable tools for   enhanced treatment tolerance.  Similarly, research on cats
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            both diagnostic imaging and therapeutic intervention in   has shown that specific dietary supplements can reduce the
            veterinary  oncology.   Integrating  nutrition  into  nuclear   severity of radiation-induced mucositis, thereby improving
                             5
            medicine protocols can enhance diagnostic accuracy,   their quality of life during treatment. 10
            enhance radiotracer uptake, and improve treatment
            efficacy. Pre-imaging dietary modifications aimed at   The field of veterinary oncology has conducted
            standardizing physiological conditions can minimize   prior studies on the relationship between nutrition and
            variability and improve the reliability of nuclear imaging   nuclear medicine. Nuclear medicine techniques such as
            studies, whereas targeted nutritional interventions can   PET and tailored radionuclide therapy are vital tools for
            mitigate radiation-induced toxicity and enhance the   both diagnostic imaging and therapeutic intervention.
            therapeutic efficacy of radionuclide therapies. The synergy   Integrating nutrition into nuclear medicine protocols
            between pet nutrition and advanced medical interventions   can potentially boost diagnostic accuracy, increase
            in veterinary oncology underscores the importance of a   radiotracer uptake, and enhance therapeutic effectiveness.
            multidisciplinary approach to patient care. Collaborative   Dietary adjustments before imaging can help normalize
            efforts among veterinarians, nutritionists, oncologists, and   physiological conditions, reduce variability, and improve
            nuclear medicine specialists are essential for developing   the reliability of nuclear imaging studies.
            evidence-based nutritional protocols tailored to the unique   A study investigating how fasting and certain dietary
            needs of each patient. Furthermore, ongoing research into   interventions affect radiotracer absorption in dogs revealed
            the interplay between nutrition and cancer treatment will   that well-regulated dietary conditions can significantly
            pave  the  way  for  innovative  therapeutic  strategies  and   improve imaging results.  In addition, research on the
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            personalized medicine.                             impact of omega-3 fatty acids has shown that these dietary
              In conclusion, integrating pet nutrition with    components can reduce the harmful effects of radiation
            radiotherapy and nuclear medicine represents a pivotal   and improve the outcomes of radionuclide therapy. 12
            advancement in veterinary oncology, offering new avenues   1.2. Contribution of the current review
            to improve treatment efficacy and patient outcomes.  By
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            recognizing the interconnectedness of nutrition with other   Building on previous studies, the present review aims to
            facets of cancer management, veterinarians can provide   clarify how pet nutrition can be optimized to support
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            comprehensive, patient-centered  care that  addresses   animals undergoing advanced cancer treatments.  This
            the complex needs of companion animals with cancer.    review focuses on understanding the combined effects of
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            Continued research, education, and collaboration will be   contemporary nutritional practices, advanced radiation,
            crucial in maximizing this synergy and advancing the field   and nuclear medicine procedures. The primary objective
            of veterinary oncology.                            is to develop scientifically supported nutritional guidelines
                                                               that optimize treatment effectiveness, reduce negative side
            1.1. Review of prior studies on nutrition and      effects, and promote the general well-being of companion
            radiotherapy in the field of veterinary oncology   animals with cancer. 14

            Radiotherapy has long been a fundamental aspect of   The combination of pet nutrition with radiotherapy
            cancer treatment in both human and veterinary medicine.   and nuclear medicine is a significant breakthrough in
            It employs ionizing radiation to specifically target and   veterinary oncology. This integration provides new
            eliminate cancer cells while minimizing damage to nearby   opportunities to enhance the effectiveness of treatment


            Volume 2 Issue 3 (2024)                         2                              doi: 10.36922/arnm.3522
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