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Advances in Radiotherapy
            & Nuclear Medicine                                   Integrating pet nutrition with radiotherapy and nuclear medicine



            2.2. Implementing dietary modifications in the field   2.2.4. Dietary protocols before medical imaging
            of veterinary oncology                             Pre-imaging dietary programs are specifically formulated
            The incorporation of pet nutrition with modern treatment   to enhance the  absorption of radiotracers and the
            methods such as radiation and nuclear medicine     precision of diagnoses in the field of nuclear medicine.
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            signifies notable progress in veterinary oncology. This   These protocols require individuals to abstain from
            section provides detailed information on several forms   eating or make changes to their diet to provide consistent
            of nutritional interventions and how they interact with   physiological conditions, which in turn minimizes
            specific treatments.                               variations in imaging investigations. A study examined the
                                                               impact of fasting and dietary interventions on radiotracer
            2.2.1. Protein-rich diet                           uptake in dogs and found that carefully controlled dietary
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            High-protein diets are essential for promoting tissue   conditions significantly improved imaging outcomes.
            healing, boosting immune system activity, and reducing   This research substantiates the utilization of pre-imaging
            the negative side effects of cancer treatment in animals.   dietary guidelines to augment the dependability of nuclear
            Protein is vital for preserving muscle mass, mending tissues   imaging examinations. 39
            harmed by radiation, and bolstering the immune system’s   2.2.5. Individualized nutritional consultation
            response to therapy. Research indicates that high-protein
            meals enhance the general well-being and treatment   Personalized nutrition counseling customizes nutritional
            tolerance of animals undergoing radiation therapy. In a   advice based on the specific requirements of each patient,
            study, dogs on a high-protein diet demonstrated improved   considering aspects such as species, breed, age, and health
            bodily condition and experienced fewer adverse effects   condition. This tailored method guarantees that nutritional
            compared to dogs on regular diets.  Similarly, high-protein   interventions  are  efficient,  enhancing  patient  adherence
                                       35
            diets were shown to boost immune activity and tissue   to therapy and overall results. 35,40  Research indicates that
            repair processes, resulting in better treatment outcomes. 36  personalized nutrition counseling effectively enhances
                                                               treatment adherence and outcomes by specifically
            2.2.2. Supplementing with antioxidants             addressing  the  requirements  of  each  patient.  A  study

            Antioxidants are crucial in reducing the harmful effects   emphasized the significance of personalized dietary
            of radiation-induced oxidative stress and damage to   programs for managing dogs undergoing radiation therapy,
            tissues. 33,34  Radiotherapy induces the production of free   demonstrating that tailored dietary plans significantly
            radicals, which have the potential to harm both healthy and   improved their health and treatment tolerance. 35
            tumor cells.  Antioxidants counteract these free radicals,   The incorporation of diverse nutritional therapies
                     29
            thereby mitigating oxidative stress and safeguarding   alongside radiotherapy and nuclear medicine greatly
            normal tissues, although at the potential cost of reducing   improves the treatment of cancer in companion animals.
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            radiotherapy efficiency. A study found that administering   High-protein meals, antioxidant and omega-3 fatty
            antioxidants to cats undergoing radiotherapy significantly   acid supplementation, dietary regimens before medical
                                                     32
            reduced the severity of radiation-induced mucositis.  This   imaging, and tailored nutrition counseling all contribute
            discovery  indicates  that  antioxidants  have  the  ability  to   to tissue regeneration, immunological function, and
            shield tissues from harm and enhance the quality of life for   treatment tolerance, while also minimizing the negative
            animals undergoing treatment.                      effects of treatment. Ongoing research and collaboration
                                                               between veterinarians, nutritionists, and oncologists are
            2.2.3. Supplementing with omega-3 fatty acids      crucial to improve and optimize these interventions in the
            Omega-3 fatty acids offer significant anti-inflammatory   field of veterinary oncology. 41
            qualities that can decrease inflammation and improve the
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            ability of animals to tolerate cancer treatment.  These fatty   2.3. Challenges in integrating nutrition with nuclear
            acids help regulate the immune response and reduce the   medicine interventions for pets
            generation  of  pro-inflammatory  cytokines.  Research  has   While the integration of nutrition with nuclear medicine
            shown that supplementing dogs with omega-3 fatty acids   interventions holds promise in optimizing treatment
            increases the effectiveness of radionuclide therapy.  This   outcomes for veterinary cancer patients, several challenges
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            improvement was achieved by lowering inflammation and   must be addressed to realize its full potential. This section
            increasing the ability of the dogs to tolerate the treatment.    explores the key challenges encountered in implementing
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            This study emphasizes the capacity of omega-3 fatty acids   nutritional strategies within the context of nuclear
            to assist animals during radiation therapy.        medicine in veterinary oncology.


            Volume 2 Issue 3 (2024)                         6                              doi: 10.36922/arnm.3522
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