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Advances in Radiotherapy
& Nuclear Medicine Image-guided interventional radiotherapy

A B C D

E F G H

Figure 8. CT-simulator-guided radioactive seed implantation. (A) Patient setup and CT scan; (B) Pre-planning; (C) Repositioning 3D-PNCT or 3D-PCT;
(D) Verification of seed needles position; (E) Confirming alignment between the seed needle position and pre-plan; (F) 125I seeds implantation; (G) Post-
plan; (H) Post-operative care. Image provided by author.
Abbreviations: 3D-PCT: 3D-printing coplanar templates; 3D-PNCT: 3D-printing non-coplanar template; CT-sim: Computed tomography simulator.

The procedures of CT-sim guided radioactive seed peer-review process conducted for this paper, directly or
implantation are as follows: (i) patient positioning setup, indirectly. Separately, other authors declared that they
and contrast-enhanced CT-sim scan; (ii) transfer of CT-sim have no known competing financial interests or personal
images to the B-TPS for designing pre-plan; (iii) accurate relationships that could have influenced the work reported
repositioning of 3D-PNCT or 3D-PCT; (iv) insertion in this paper.
of seed needles; (v) CT-sim scan to confirm alignment
between seed needle position and pre-plan; (vi) 125I seeds Author contributions
implantation; (vii) CT-sim scan to assess the displacement Conceptualization: Junjie Wang, Ping Jiang
of the 125I seeds, and supplementation of additional seeds, Writing – original draft: Qiman Han, Yi Chen
if necessary; and (viii) transferring patients back toward Writing – review & editing: Junjie Wang, Zhe Ji, Yi Chen,
(Figures 7 and 8). Bin Qiu

6. Conclusion Ethics approval and consent to participate
The advent of CT-sim has ushered in an era where Not applicable.
interventional brachytherapy has attained swift
advancements, bringing forth the establishment of Consent for publication
standardized and harmonized technical systems that lay a Patients gave consent to publish their images in this study.
concrete foundation for a revolutionary transformation in
tumor diagnosis and RT. Availability of data

Acknowledgments Not applicable.
None. References

Funding 1. Hwang EJ, Park CM, Yoon SH, Lim HJ, Goo JM. Risk factors
for haemoptysis after percutaneous transthoracic needle
None. biopsies in 4,172 cases: Focusing on the effects of enlarged main
pulmonary artery diameter. Eur Radiol. 2018;28:1410-1419.
Conflict of interest doi: 10.1007/s00330-017-5101-8
Junjie Wang and Ping Jiang are the Editor-in-Chief and 2. Kawashima H, Ohno E, Ishikawa T, et al. Endoscopic
the Editorial Board Member of the journal, respectively, management of perihilar cholangiocarcinoma. Dig Endosc.
but were not in any way involved in the editorial and 2022;34:1147-1156.

Volume 2 Issue 3 (2024) 7 doi: 10.36922/arnm.3781