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Brain & Heart





                                        CASE REPORT
                                        Pedunculated left endoventricular thrombosis

                                        complicated by cerebral stroke in patient with
                                        suspected peripartum cardiomyopathy: A

                                        case report



                                                                                    2†
                                                                                                    1†
                                                                        2†
                                        Kristian Galanti , Roberta Magnano , Laura Pezzi , Mario Di Marino ,
                                                     1†
                                        Alberto D’Alleva , Daniele Forlani , Piergiusto Vitulli ,
                                                                     2
                                                      2
                                                                                      2
                                                        3
                                        Vincenzo Di Egidio , Gabriele Di Giammarco , Leonardo Paloscia ,
                                                                                                2
                                                                              4
                                        Sabina Gallina , and Massimo Di Marco *
                                                     1
                                                                          2†
                                        1 Department of Neuroscience, Imaging and Clinical Sciences, G. D’Annunzio University of Chieti-
                                        Pescara, 66100, Chieti, Italy
                                        2 Department of Cardiology and ICCU, Santo Spirito Hospital, Pescara, 65124, Italy
                                        3 Department of Radiology, Santo Spirito Hospital, Pescara, 65124, Italy
                                        4 Department of Cardiac Surgery, G. D’Annunzio University of Chieti-Pescara, Chieti, 66100, Italy
                                        Abstract
                                        Peripartum cardiomyopathy (PPMC) is an infrequent form of cardiomyopathy, whose
            † These authors contributed equally   main presentation is characterized by systolic dysfunction that commonly emerges
            to this work.               in the early postpartum period. Acute heart failure symptoms such as congestion
            *Corresponding author:      and dyspnea are common manifestations of PPMC. Here, we present a case of a
            Massimo Di Marco            32-year-old female who, after hospitalization, manifested dyspnea and thoracic
            (dimarcom@hotmail.com)      pain linked to the findings a left endoventricular thrombus. After the admission to
            Citation: Galanti K, Magnano V,   the intensive cardiovascular care unit, heart failure and anticoagulant therapies as
            Pezzi V, et al., 2023, Pedunculated   well as non-steroidal anti-inflammatory drugs were administered, leading to initial
            left endoventricular thrombosis
            complicated by cerebral stroke in   improvement of the left ventricular global function. Five days after the treatment,
            patient with suspected peripartum   the patient experienced aphasia  and right hemiplegia. The cerebral angiography
            cardiomyopathy: A case report.   documented an M1 segment occlusion. After treating the occlusion with stent
            Brain & Heart, 1(2): 1115.
            https://doi.org/10.36922/bh.1115  retriever thrombectomy, the symptoms regressed and she attained full recovery.
                                        Therefore, surgical thrombectomy should be prioritized as the treatment approach
            Received: June 21, 2023
                                        to removing the pedunculated left ventricular thrombus, considering the apical
            Accepted: October 12, 2023  morphology of the pedunculated left ventricular thrombus and if the anticoagulant
            Published Online: November 3,   therapy gives rise to side effects.
            2023
            Copyright: © 2023 Author(s).   Keywords: Peripartum cardiomyopathy; Apical thrombus; Stroke; Stent retriever
            This is an Open-Access article
            distributed under the terms of the   thrombectomy; Surgical thrombectomy
            Creative Commons Attribution
            License, permitting distribution,
            and reproduction in any medium,
            provided the original work is
            properly cited.             1. Background
            Publisher’s Note: AccScience   Peripartum cardiomyopathy (PPMC) is a rare, idiopathic cardiomyopathy, defined
            Publishing remains neutral with   by global systolic dysfunction that emerges in late pregnancy period or more often in
            regard to jurisdictional claims in                 [1]
            published maps and institutional   the early postpartum period . It is difficult to diagnose such a condition in patients
            affiliations.               with previous established cardiomyopathy and for this reason in 2010, the European


            Volume 1 Issue 2 (2023)                         1                         https://doi.org/10.36922/bh.1115
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