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Brain & Heart                                                        Balloon valvuloplasty for aortic stenosis




                         A                                     B


























            Figure 8. Pressure tracings from the left ventricle and aorta were recorded simultaneously (A) before balloon aortic valvuloplasty (BAV), indicating a
            significant aortic valve pressure gradient. Following BAV (B), the aortic valve pressure gradient was abolished. The fall in diastolic pressure in the aorta
            following BAV is probably due to the development of aortic insufficiency. Reproduced from Agu and Rao. 12
























                                                               Figure  10. Graph depicting outcomes of balloon aortic valvuloplasty
            Figure  9. Graph depicting outcomes of balloon aortic valvuloplasty   (BAV). Both the aortic valve peak gradients (left panel) and percentage
            (BAV). Significant (p  < 0.001) decline in aortic valve peak gradients   drop (right panel) decrease (p  = 0.001) after BAV. Mean ± standard
            after BAV is shown: Pre (before) vs. Post (after) BAV. Repeat cardiac   deviation (SD) is indicated. Notes: Pre: before BAV; Post: after BAV.
            catheterization at a mean of 16 months after BAV in 15 patients revealed   Reproduced from Rao. 11
            an increase (p < 0.01) at intermediate-term follow-up (ITFU). However,
            the pressure gradients are lower (p  < 0.001) than those before BAV.
            Reproduced from Galal et al. 19                    5. Late follow-up outcomes
                                                               Late follow-up (more than a median or mean of 5 years)
            were found to be age under 3 years and post-BAV residual
            aortic gradients exceeding 30  mmHg. 18,19  Notably, the   outcomes post-BAV have been evaluated by several
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            higher the number of risk factors, the greater the probability   cardiologists. Hawkins et al.,  Kuhn et al.,  and Demkow
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            of obstruction (Figure 16). 18,19  Other investigators  studied   et  al.  observed the need for surgical intervention in
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            this issue  but could  not identify any key  factors. The   33% to 45% of patients at long-term follow-up, either to
            re-stenosed valve can be successfully balloon dilated by   address recurrent AVS or newly developed AI. Reports by
            repeat BAV (Figure 17). 64                         other investigators were summarized elsewhere.  In our
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            Volume 2 Issue 3 (2024)                         4                                doi: 10.36922/bh.2914
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