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Brain & Heart                                                        Balloon valvuloplasty for aortic stenosis

























            Figure  19. Graph depicting event-free rates following balloon aortic
            valvuloplasty. Confidence limits are set at 70%, indicated with dashed   Figure  21. The magnitude of aortic insufficiency (AI) observed at
            lines. Actuarial rates without intervention are 80%, 76%, 76%, and 76% at   late  follow-up  (assessed  through  Doppler)  following  balloon  aortic
            1, 2, 5, and 9 years, respectively. Reproduced from Galal et al. 19  valvuloplasty (BAV) plotted against balloon/annulus ratios used during
                                                               BAV. There is an insignificant correlation between these  values, with
                                                               an R of 0.36, suggesting that the balloon/annulus ratios are unlikely to
                                                               be a causative factor for the development of AI. It is further noted that
                                                               grade 3+ AI was observed with large ranges of balloon/annulus ratios.
                                                               Reproduced from Galal et al. 19

                                                               with residual post-BAV gradients <30 mmHg. Repeat BAV
                                                               emerges as a potential candidate for effectively addressing
                                                               restenosis. Data from late follow-ups indicate persistent
                                                               relief of aortic valve narrowing, no significant additional
                                                               restenosis, and the onset of AI in 25% of patients. Actuarial
                                                               rates of no re-intervention at 5 and 10 years after BAV were
                                                               approximately 75%  and 60%, respectively. Based on the
                                                               author’s own experience and that of others, it is concluded
                                                               that BAV is the primary treatment choice for the relief of
                                                               AVS. However, the occurrence of AI at late follow-up is
                                                               significant. Methods to prevent the late onset of AI should
            Figure 20. The magnitude of aortic insufficiency (AI) observed on the   be pursued. Given the late occurrence of AI, some cases
            day following balloon aortic valvuloplasty (BAV) plotted against AI at   requiring surgery, it is wise to closely adhere to guidelines
            long-term follow-up. There is a discernible relationship between these   for BAV  intervention and to avoid  BAV  for milder or
            two parameters (R = 0.71). Reproduced from Galal et al. 19  marginal gradients.

            7. Summary and conclusions                         Acknowledgments

            Subsequent to the publication of BAV by Lababidi in 1983,   A substantial number of echocardiographic pictures
            the procedure has been widely adopted by cardiologists   were used as figures in this paper, with a sizable portion
            to manage AVS. The indications for BAV were similar   originating from examinations conducted at the Children’s
            to  those  utilized  for  surgery.  The  recommended  B/A   Memorial Hermann Hospital in Houston, Texas. I take this
            ratio  was between  0.8 and 1.0. BAV is  most frequently   opportunity to thank the sonographers for their diligence
            performed through the femoral artery; however, due   in securing high-quality echocardiograms.
            to the potential for femoral artery injury in neonates,   Funding
            trans-umbilical arterial or trans-venous routes may be
            used. A decrease in aortic valve peak pressure gradients   None.
            was detected immediately following BAV and in short-
            term follow-up. However, restenosis developed in 25% of   Conflict of interest
            patients, particularly in those under 3 years old and those   The author declares no conflicts of interest.


            Volume 2 Issue 3 (2024)                         7                                doi: 10.36922/bh.2914
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