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Brain & Heart                                                                Cardioneuroablation for VMB



            personnel may limit widespread adoption, particularly in   Consent for publication
            resource-constrained settings. Finally, ethical concerns
            arise regarding the potential replacement of pacemaker   A written informed consent was obtained from each of the
            implantation with a relatively novel intervention like CNA.   subjects to publish their data and images.
            Balancing innovation with patient safety and efficacy will   Availability of data
            remain a key focus of the ongoing research efforts in this
            field.                                             The data used in this article will be shared upon reasonable
                                                               request to the corresponding author.
            5. Conclusion
                                                               References
            CNA presents a promising intervention for patients with
            VMB, demonstrating significant success in reducing   1.   Goldberger JJ, Arora R, Buckley U, Shivkumar K. Autonomic
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                                                                  Cardiol. 2019;73(10):1189-1206.
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            systematic review and meta-analysis, reveal that this      doi: 10.1016/j.jacc.2018.12.064
            procedure is highly effective and has a low complication   2.   Baschieri F, Cortelli P. Circadian rhythms of cardiovascular
            rate, underscoring its potential as a standard treatment   autonomic function: Physiology and clinical implications in
            option.                                               neurodegenerative diseases. Auton Neurosci. 2019;217:91-101.
            Acknowledgments                                       doi: 10.1016/j.autneu.2019.01.009
                                                               3.   Alboni P, Holz A, Brignole M. Vagally mediated
            None.
                                                                  atrioventricular block: pathophysiology and diagnosis. Heart.
            Funding                                               2013;99(13):904-908.
                                                                  doi: 10.1136/heartjnl-2012-303220
            This  work  was  supported  by  the  Shanghai  Municipal
            Key Clinical Specialty (shslczdzk06204), the Shanghai   4.   Aktaa S, Abdin A, Arbelo E,  et al. European Society of
            Professional Technical Service Platform for Biological   Cardiology Quality Indicators for the care and outcomes
                                                                  of cardiac pacing: Developed by the Working Group for
            Sample  and   Database  of  Cardiovascular  and       Cardiac Pacing Quality Indicators in collaboration with
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            (19MC1910500), and the Shanghai Municipal Health
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                                                               5.   Glikson M, Nielsen JC, Kronborg MB,  et al. 2021 ESC
            Conflict of interest                                  Guidelines on cardiac pacing and cardiac resynchronization
            Yan Yao is an Editor-in-Chief of this journal and Guest   therapy: Developed by the Task Force on cardiac pacing and
                                                                  cardiac resynchronization therapy of the European Society
            Editor of this special issue but was not in any way involved   of Cardiology (ESC) With the special contribution of the
            in the editorial and peer-review process conducted for   European  Heart Rhythm Association (EHRA).  Rev Esp
            this paper, directly or indirectly. Separately, other authors   Cardiol (Engl Ed). 2022;75(5):430.
            declared that they have no known competing financial      doi: 10.1016/j.rec.2022.04.004
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            influenced the work reported in this paper.        6.   Pachon JC, Pachon EI, Pachon JC, et al. Cardioneuroablation-
                                                                  -new treatment for neurocardiogenic syncope, functional
            Author contributions                                  AV block and sinus dysfunction using catheter RF-ablation.
                                                                  Europace. 2005;7(1):1-13.
            Conceptualization: Yan Yao, Jun Pu
            Investigation: Minhua Zang, Bin Xu                    doi: 10.1016/j.eupc.2004.10.003
            Methodology: Guangyu Li, Guangyu Wang, Zhiqing Liao,   7.   Pachon MJ, Pachon ME, Lobo TJ,  et al. Syncopal high-
               Lihui Zheng                                        degree AV block treated with catheter RF ablation without
            Writing–original draft: Feng Hu, Yali Wang            pacemaker implantation.  Pacing Clin Electrophysiol.
            Writing–review & editing: Yan Yao, Jun Pu             2006;29(3):318-322.
                                                                  doi: 10.1111/j.1540-8159.2006.00340.x
            Ethics approval and consent to participate
                                                               8.   Scanavacca M, Hachul D, Pisani C, Sosa E. Selective vagal
            A written informed consent was obtained from all patients   denervation of the sinus and atrioventricular nodes, guided
            in this study.                                        by vagal reflexes induced by high frequency stimulation,


            Volume 3 Issue 1 (2025)                         8                                doi: 10.36922/bh.4824
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