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Brain & Heart                                                   Thrombectomy for stroke after cardiac surgery



            one had AF before surgery, emphasizing the important role   Timely MT treatment has a beneficial effect on neurological
            of AF in the development of LVO stroke. Three patients   function and greatly improves patients’ prognosis.
            had reduced ejection fraction (≤50%) after cardiac surgery   Thus, given its advantages, the usage of multimodal CT
            on echocardiography in this study. Heart failure is the   evaluation should be promoted and popularized in clinical
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            second leading cause of cardiogenic stroke,  and the   settings. Nevertheless, further studies employing larger
            mechanisms of thromboembolic events  in patients  with   sample sizes are warranted to improve the outcomes in this
            heart failure include blood stasis, endothelial dysfunction,   special patient cohort, since severe neurological deficits
            and a hypercoagulable state.  Therefore, greater attention   and even mortality occur in certain patients receiving MT.
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            should be paid to ischemic stroke in patients with impaired
            cardiac function after cardiac surgery.            Acknowledgments
              The patients included in this study mainly underwent   None.
            CABG and valve surgery, as these two surgeries are the   Funding
            most common. In this study, most patients who underwent
            thrombectomy had symptoms that occurred 2 – 5  days   This work was supported by the National High-Level
            after surgery, indicating that the diagnosis of stroke in these   Hospital Clinical Research Funding (2022-GSP-TS-4).
            patients can be made during the stable post-operative period
            or when they wake up from general anesthesia.  We found   Conflict of interest
                                                 19
            that even if the patient had an in-hospital stroke, there was   Shujuan Li is an Editorial Board Member of this journal but
            still a long duration from LKW to recanalization. A scientific   was not in any way involved in the editorial and peer-review
            statement   on in-hospital stroke  reported that although   process conducted for this paper, directly or indirectly.
                   30
            patients with in-hospital stroke had short admission process   Separately, other authors declared that they have no known
            and transfer times, their evaluation and treatment were often   competing financial interests or personal relationships that
            delayed compared to patients with community-onset stroke,   could have influenced the work reported in this paper.
            contributing to higher rates of morbidity and mortality in this
            patient population. It is difficult to distinguish between a new   Author contributions
            stroke and the consequences of periprocedural medications.   Conceptualization: Shujuan Li, Yao Feng
            In addition, the in-hospital stroke treatment process needs   Formal analysis: Yao Feng, Guitao Zhang
            to be optimized, as there is still a long waiting time between   Investigation: Guitao Zhang, Bin Lv
            symptom discovery and entering the interventional therapy.   Methodology: Na Zhao, Bincheng Wang
            Addressing this requires collaboration among multiple   Writing – original draft: Yao Feng, Bincheng Wang
            hospital  departments,  including  the  cardiac  surgery,   Writing – review & editing: Shujuan Li, Bin Lv
            radiology, neurology, interventional operating rooms, and
            medical affairs departments.                       Ethics approval and consent to participate
              This  study  has some  limitations  that  must  be noted.   The Research Ethics Committee of Fuwai Hospital, Chinese
            Firstly, the results need to be interpreted with caution,   Academy of Medical Sciences, approved this study (Ethics
            given the limited sample size. Secondly, we only reported   approval code: 2022-1848). Data were collected retrospectively,
            patients with LVO stroke who underwent MT; therefore,   and  no  further  procedure  was  performed;  hence,  the
            the prognosis of patients with LVO stroke who did not   requirement to obtain informed consent was waived.
            undergo thrombectomy remains unclear. In addition, the
            present study did not attempt to delineate whether patient   Consent for publication
            prognosis can be significantly improved (90-day  mRS   All images used in this study were anonymized; hence, the
            score 0 – 1) when the diagnostic and treatment processes   requirement to obtain consent for publication was waived.
            are optimized, given the relatively long waiting time
            between  symptom  discovery  and  treatment  process.   Availability of data
            Nevertheless, our case series supplements the evidence for   The data used in this study will be made available from the
            MT in this special population and provides a reference for   corresponding authors upon request.
            future large-sample cohort studies.
                                                               References
            5. Conclusion
                                                               1.   Madeira M, Martins C, Koukoulis G, Marques M, Reis J,
            The  present  study  illustrates  the  impact  of  multimodal   Abecassis M. Mechanical thrombectomy for stroke after
            CT-guided MT on the prognosis of LVO stroke patients.   cardiac surgery. J Card Surg. 2016;31:517-520.


            Volume 3 Issue 1 (2025)                         7                                doi: 10.36922/bh.4141
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