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Brain & Heart                                             Stroke risk in Nigerians with diabetes and hypertension




                          Identification  Records identified at Imam  Records identified at Imam

                                                                    Halliru Hospital
                                      Wali Hospital
                                                                      (n = 416)
                                        (n = 517)

                          Screening               Records screened            Records excluded due to
                                                                                missing information
                                                      (n = 933)
                                                                                   (n = 415)



                                                                             Records excluded due to
                          Eligibility              Records assessed for      inclusion/exclusion criteria
                                                       eligibility
                                                       (n = 518)
                                                                                   (n = 318)



                          Included                Records included in the
                                                        study
                                                       (n = 200)


                                               Figure 1. Flowchart of the study selection

            and 19 (25.3%) males in this cohort. Most of the participants
            in this cohort identified themselves as housewives
            (74.7%), while only 10 (13.3%) and 9 (12.0%) participants
            identified themselves as civil servants and business owners,
            respectively. The top clinical presentations reported by
            participants in this cohort were sudden onset of unilateral
            body weakness (45 [60.0%]), followed by sudden onset of
            sensory loss (21 [28%]), sudden loss of vision (5 [6.7%]),
            and sudden loss of speech (4 [5.3%]). Majority of the
            participants (43 [57.3%]) had blood pressure readings
            categorized as Stage 1 HTN (SBP 140 – 159 mmHg and
            DBP 90 – 99 mmHg), while about 24 (32.0%) had Stage 2
            HTN (SBP ≥160 mmHg and DBP ≥100 mmHg). Majority    Figure 2. Distribution of age of the patients by their gender
            of the females in this cohort were within the age range of
            61 – 70 years, whereas most of the male participants were   7  (10.4%) participants  identified themselves  as  civil
            in the age range of 71 – 80 years. This is shown in Figure 2   servants and business owners, respectively. Furthermore,
            below.                                             as in the hypertensive cohort, the top clinical presentations
                                                               reported by participants in this cohort were sudden onset
            3.3. Diabetes cohort                               of unilateral body weakness (41 [61.2%]), followed by
            As mentioned earlier, 933  patients were identified with   sudden onset of sensory loss (17 [25.4%]), sudden loss of
            outpatient visits at the two general hospitals, including   vision (5 [7.4%]), and sudden loss of speech (4 [6.0%]).
            200  patients  with  clinical  features  consistent  with  the   Majority of the participants (37 [55.2%]) had their fasting
            WHO  definition  of  stroke  from  January  2015  through   blood sugar (FBS) in the range of 12 – 18 mmol/dL. About
            August 2020. Of the 200 patients, 67 (33.5%) had diabetes,   22 (32.8%) participants had an FBS ≥19 mmol/dL, while
            constituting the diabetic cohort. Majority of the participants   only 8 (11.9%) participants had an FBS of 5 – 11 mmol/dL.
            in this cohort were in the age range of 61 – 70 years (26.9%),   Similarly, majority of the females in this cohort were also
            with 50 (74.6%) females and 17 (25.4%) males. As in the   within age range of 61 – 70 years, whereas most of the male
            hypertensive cohort, majority of the participants identified   participants were in the age range of 71 – 80 years. This is
            themselves as housewives (77.6%), only 8  (11.9%) and   shown in Figure 3 below.


            Volume 3 Issue 1 (2025)                         4                                doi: 10.36922/bh.5722
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