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Eurasian Journal of Medicine and
Oncology
Research on hypoxia and ECM in cancer

Acknowledgments doi: 10.7150/jca.44313

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This work was financially supported by the Luzhou doi: 10.1038/onc.2009.441
Municipal People’s Government – Southwest Medical 5. Vaupel P, Höckel M, Mayer A. Detection and characterization
University Science and Technology Strategic Cooperation of tumor hypoxia using pO2 histography. Antioxid Redox
(2024LZXNYDJ074), Southwest Medical University Signal. 2007;9(8):1221-1235.
(05/00170050), Science and Technology Project of Luzhou doi: 10.1089/ars.2007.1628
City (2023JYJ051), and the Cooperative Project between 6. Zhang T, Suo C, Zheng C, Zhang H. Hypoxia and Metabolism
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7. Frantz C, Stewart KM, Weaver VM. The extracellular matrix
The authors declare no potential conflicts of interest with at a glance. J Cell Sci. 2010;123(Pt 24):4195-4200.
respect to the research, authorship, and/or publication of
this article. doi: 10.1242/jcs.023820
8. Gkretsi V, Stylianopoulos T. Cell adhesion and matrix
Author contributions stiffness: Coordinating cancer cell invasion and metastasis.
Conceptualization: Xin Jiang, Chun Zhang, Qiuyu Liu Front Oncol. 2018;8:145.
Funding acquisition: Chun Zhang doi: 10.3389/fonc.2018.00145
Investigation: Xin Jiang 9. Li X, Wang J. Mechanical tumor microenvironment and
Methodology: Xin Jiang, Qiuyu Liu transduction: Cytoskeleton mediates cancer cell invasion
Project administration: Chun Zhang, Qiuyu Liu and metastasis. Int J Biol Sci. 2020;16(12):2014-2028.
Resources: Jiaxin Yang, Xue Fan
Validation: Lilan Ou doi:10.7150/ijbs.44943
Visualization: Xin Jiang, Lilan Ou, Qiuyu Liu 10. Stanton AE, Tong X, Yang F. Extracellular matrix type
Writing-original draft: Xin Jiang modulates mechanotransduction of stem cells. Acta
Writing-review & editing: Chun Zhang, Qiuyu Liu Biomater. 2019;96:310-320.
Ethics approval and consent to participate doi: 10.1016/j.actbio.2019.06.048

The content of this article has no ethical implications. 11. Walker C, Mojares E, Del Río Hernández A. Role of
extracellular matrix in development and cancer progression.
Consent for publication Int J Mol Sci. 2018;19(10):3028.
Not applicable. doi: 10.3390/ijms19103028
12. Pickett MR, Chen YI, Kamra M, et al. Assessing the impact
Availability of data of extracellular matrix fiber orientation on breast cancer
cellular metabolism. Cancer Cell Int. 2024;24(1):199.
The data that support the findings of this study are available
from the authors on reasonable request. doi: 10.1186/s12935-024-03385-3
13. Willumsen N, Leitzel K, Ali SM, et al. Extracellular matrix
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Volume 9 Issue 1 (2025) 187 doi: 10.36922/ejmo.7116