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Volume 9 ǀ Issue 1 ǀ March 2025 ǀ Page 1 – 262 ǀ

                                                        Eurasian Journal of Medicine and Oncology


                                                                           https://accscience.com/journal/EJMO


           CONTENTS





            REVIEW ARTICLES
            1       Advances and applications of single-cell RNA sequencing in deciphering the tumor
                    microenvironment of malignant skin tumors
                    Yiting Feng, Lanlan Liu, Chunlan Hu, Jie Sun, Mingzhu Yin, Xin Li
            16      Variants of unknown significance in BRCA1 and BRCA2 among breast cancer patients in
                    Middle Eastern and North African populations: A systematic review
                    Oubaida Elbiad, Oumaima Mazour, Khalid Ennibi, Bouabid Badaoui, Abdelilah Laraqui
            46      Prophetic medicine: An integrative medicine model
                    Saud M. Alsanad
            64      Microbial challenges from tooth surface to implant damage: A review
                    Sura Dakhil Jassim, Fatima Malik Abood, Anfal Ihsan Jasim
            76      Polymorphisms in insulin regulation and type 2 diabetes: A narrative review of risk and
                    management in Asian populations
                    Farizky Martriano Humardani, Sulistyo Emantoko Dwi Putra, Ratih Asmana Ningrum, I. Wayan Arsana Wiyasa, Lisa Thalia
                    Mulyanata, Risma Ikawaty, Agustina Tri Endharti


            ORIGINAL RESEARCH ARTICLES
            92      Next-generation sequencing and bioinformatics analysis in breast cancer research: Insights
                    from Western Kazakhstan
                    Marzhan Aitmagambetova, Nazar Seidalin, Dmitriy Babenko, Gaziza Smagulova, Saule Balmagambetova, Arip Koishybaev,
                    Anar Tulyayeva1, Nurgul Kereyeva, Dinara Zholmukhamedova, Azamat Zharylgapov, Nauryzbay Imanbayev, Nurgul
                    Ablakimova
            108     Predictive value of the HEART score for coronary lesions based on the SYNTAX score in
                    patients with non-ST-elevation acute coronary syndrome
                    Phan Thai Hao, Vo Anh Tai
            115     Advancing oncology care with AI-powered virtual assistants and chatbots: A qualitative
                    exploration of future potential and challenges
                    Hemalatha Senthilmahesh, Muthuvairavan Pillai Nagappan, Somavarapu N. C. Shekhar, Anbarasa A. Pandian, Pullela S. V.
                    V. S. R. Kumar, Ramesh Tumaati
            133     Clinical and demographic predictors of heart failure outcomes: A machine learning
                    perspective
                    Shivaprasad Chitta, Supriya Chandu, Krishna Chaitanya Katha, Syam Sundar Junapudi, Vinod Kumar Yata, Sunil Junapudi
            144     Anticancer potential of flavonoids isolated from Pistacia chinensis against glioblastoma
                    (U87) cell line: Extensive in vitro and in silico research
                    Abdur Rauf, Soonmin Ho, Muhammad Umer Khan, Iqra Khurram, Zuneera Akram, Yahya S. Al-Awthan, Omar S. Bahattab,
                    Marcello Iriti
            159     Unveiling the molecular complexities of cardiovascular diseases: Insights into signaling
                    proteins and therapeutic targets
                    Emad Fadhal
            168     Research on hypoxia and the extracellular matrix in cancer: A visualization analysis
                    Xin Jiang, Lilan Ou, Xue Fan, Jiaxin Yang, Chun Zhang, Qiuyu Liu
            193     Cost-effectiveness of nivolumab plus chemotherapy for advanced gastric/gastroesophageal
                    junction/esophageal adenocarcinoma in the United States
                    Jin Zhou, Wei Oy-Yang, Xia Yin, Han Zhan, Jin Luo, Ge-Li Li
            204     Clinical effect of MaiLuoShuTong pills combined with dalteparin on parathyroid function
                    recovery after total thyroidectomy
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