Page 96 - EJMO-9-1
P. 96

Eurasian Journal of Medicine and
            Oncology
                                                                                        T2D polymorphisms in Asians


               India. Diabetes Epidemiol Manag. 2022;6:100066.    in adiponectin gene (rs266729) with metabolic syndrome
                                                                  and diabetes mellitus type 2 in adult obese subjects. Eur Rev
               doi: 10.1016/j.deman.2022.100066
                                                                  Med Pharmacol Sci. 2020;24(20):10646-10652.
            28.  Holmkvist J, Banasik K, Andersen G,  et al. The Type  2      doi: 10.26355/eurrev_202010_23422
               diabetes associated minor allele of rs2237895 KCNQ1
               associates  with  reduced  insulin  release  following  an  oral   39.  Hung YJ, Lee CH, Chu NF, Shieh YS. Plasma protein growth
               glucose load. PLoS One. 2009;4(6):e5872.           arrest-specific 6 levels are associated with altered glucose
                                                                  tolerance, inflammation, and endothelial dysfunction.
               doi: 10.1371/journal.pone.0005872
                                                                  Diabetes Care. 2010;33(8):1840-1844.
            29.  Wu HH, Li YL, Liu NJ, et al. TCF7L2 regulates pancreatic
               β-cell function through PI3K/AKT signal pathway. Diabetol      doi: 10.2337/dc09-1073
               Metab Syndr. 2019;11:55.                        40.  Hsiao  FC,  Lin  YF,  Hsieh PS,  et al.  Circulating  growth
                                                                  arrest-specific 6 protein is associated with adiposity,
               doi: 10.1186/s13098-019-0449-3
                                                                  systemic inflammation, and insulin resistance among
            30.  Zhou Y, Park SY, Su J, et al. TCF7L2 is a master regulator   overweight and obese adolescents. J Clin Endocrinol Metab.
               of insulin production and processing.  Hum Mol Genet.   2013;98(2):E267-E274.
               2014;23(24):6419-6431.
                                                                  doi: 10.1210/jc.2012-3179
               doi: 10.1093/hmg/ddu359
                                                               41.  Su S, Chiang C, Hsieh C,  et al. Growth arrest‐specific 6
            31.  Pang DX, Smith AJ, Humphries SE. Functional analysis of   modulates adiponectin expression and insulin resistance in
               TCF7L2 genetic variants associated with type  2 diabetes.   adipose tissue. J Diabetes Investig. 2021;12(4):485-492.
               Nutr Metab Cardiovasc Dis. 2013;23(6):550-556.
                                                                  doi: 10.1111/jdi.13412
               doi: 10.1016/j.numecd.2011.12.012
                                                               42.  Lee CH, Chu NF, Shieh YS, Hung YJ. The growth arrest-
            32.  Phu S, Thida A, Maung KK, Chit TT. Single nucleotide   specific 6 (Gas6) gene polymorphism c.834+7G>A is
               polymorphism at rs7903146 of transcription factor 7-like   associated with type  2 diabetes.  Diabetes Res Clin Pract.
               2 gene among subjects with type  2 diabetes mellitus in   2012;95(2):201-206.
               Myanmar. J ASEAN Fed Endocr Soc. 2023;38(1):41-47.
                                                                  doi: 10.1016/j.diabres.2011.09.013
               doi: 10.15605/jafes.037.S2
                                                               43.  Chistiakov DA, Potapov VA, Khodirev DS, Shamkhalova MS,
            33.  Najjar SM, Perdomo G. Hepatic insulin clearance:   Shestakova  MV,  Nosikov  VV.  The  PPARγ  Pro12Ala
               Mechanism and physiology.  Physiology (Bethesda).   variant  is  associated  with  insulin  sensitivity  in  Russian
               2019;34(3):198-215.                                normoglycaemic and type 2 diabetic subjects. Diab Vasc Dis
                                                                  Res. 2010;7(1):56-62.
               doi: 10.1152/physiol.00048.2018
                                                                  doi: 10.1177/1479164109347689
            34.  Duckworth WC, Bennett RG, Hamel FG. Insulin degradation:
               Progress and potential. Endocr Rev. 1998;19(5):608-624.  44.  Gong  S,  Han  X, Li  M,  et  al.  Genetics  and  clinical
                                                                  characteristics of PPARγ variant-induced diabetes in a
               doi: 10.1210/edrv.19.5.0349
                                                                  Chinese  Han  population.  Front Endocrinol (Lausanne).
            35.  Kullenberg H, Rossen J, Johansson UB, et al. Increased levels   2021;12:677130.
               of insulin-degrading enzyme in patients with type 2 diabetes
               mellitus. Endocrine. 2022;77(3):561-565.           doi: 10.3389/fendo.2021.677130
                                                               45.  Li S, He C, Nie H,  et al. G  Allele of the rs1801282
               doi: 10.1007/s12020-022-03123-7
                                                                  polymorphism  in  PPARγ  gene  confers  an  increased  risk
            36.  Merino B, Fernández-Díaz CM, Parrado-Fernández C,   of obesity and hypercholesterolemia, while T allele of the
               et al. Hepatic insulin-degrading enzyme regulates glucose   rs3856806 polymorphism displays a protective role against
               and insulin homeostasis in diet-induced obese mice.   dyslipidemia: A systematic review and meta-analysis. Front
               Metabolism. 2020;113:154352.                       Endocrinol (Lausanne). 2022;13:919087.
               doi: 10.1016/j.metabol.2020.154352                 doi: 10.3389/fendo.2022.919087
            37.  De Luis DA, Izaola O, de la Fuente B, Primo D, Fernandez   46.  Frederiksen L. Studies of the Pro12Ala polymorphism
               Ovalle H, Romero E. rs1501299 Polymorphism in the   of the  PPAR-gene in the Danish MONICA cohort:
               adiponectin gene and their association with total adiponectin   Homozygosity of the Ala Allele confers a decreased risk of
               levels, insulin resistance and metabolic syndrome in obese   the insulin resistance syndrome. J Clin Endocrinol Metab.
               subjects. Ann Nutr Metab. 2016;69(3-4):226-231.    2002;87(8):3989-3992.
               doi: 10.1159/000453401                             doi: 10.1210/jcem.87.8.8732
            38.  De Luis DA, Izaola O, Primo D, Aller R. Relation of a variant   47.  Tai ES, Corella D, Deurenberg-Yap M,  et al. Differential


            Volume 9 Issue 1 (2025)                         88                              doi: 10.36922/ejmo.7549
   91   92   93   94   95   96   97   98   99   100   101