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Eurasian Journal of
            Medicine and Oncology                                                     Ovarian cyst differentiation score



            Table 1. Characteristics of patients with ovarian endometriomas and ovarian cystadenomas

            Characteristics                    Training cohort                        Validation cohort
                                    Cystadenomas   Endometriotic   p       Cystadenomas   Endometriotic   p
                                      (n=83)        cysts (n=68)             (n=31)       cysts (n=20)
            CA125, (%)                                            <0.001                                 0.009
             Normal                   74 (89.2)      13 (19.1)               26 (83.9)       9 (45)
             Elevated                 9 (10.8)       55 (80.9)               5 (16.1)       11 (55)
            Age (years), (%)                                      <0.001
             ≤20                       6 (7.2)        1 (1.5)                                            <0.001
             21 – 50                  31 (37.3)      66 (97.1)               19 (61.3)       1 (5)
             >50                      46 (55.4)       1 (1.5)                11 (35.5)      19 (95)
            Wall thickness, (%)                                   <0.001      1 (3.2)        0 (0)       <0.001
             <2 mm                    61 (73.5)       7 (10.3)               31 (100)        1 (5)
             ≥2 mm                    22 (26.5)      61 (89.7)                0 (0)         19 (95)
            Marginal adhesions, (%)                               <0.001                                 <0.001
             Absent                   78 (94)        18 (26.5)               31 (100)        6 (30)
             Present                   5 (6)         50 (73.5)                0 (0)         14 (70)
            Density heterogeneity, (%)                            <0.001                                 0.002
             Uniform                  69 (83.1)      22 (32.4)               23 (74.2)       5 (25)
             Mild to moderate         11 (13.3)      43 (63.2)               8 (25.8)       15 (75)
             Severe                    3 (3.6)        3 (4.4)                 0 (0)          0 (0)
            Contour, (%)                                          <0.001
             Regular                  67 (80.7)      15 (22.1)
             Irregular                16 (19.3)      53 (77.9)
            Pelvic fluid, (%)                                     <0.001
             Absent                   71 (85.5)      41 (60.3)
             Present                  12 (14.5)      27 (39.7)
            Longitudinal diameter, (%)                            <0.001
             <5 cm                     8 (9.6)       18 (26.5)
             5 – 10 cm                30 (36.1)      43 (63.2)
             ≥10 cm                   45 (54.2)       7 (10.3)
            Clinical symptoms, (%)                                0.010
             Asymptomatic             37 (44.6)       34 (50)
             Dysmenorrhea, infertility  10 (12)      18 (26.5)
             Abdominal pain, bloating  35 (42.2)     14 (20.6)
             Others                    1 (1.2)        2 (2.9)
            Cyst number, (%)                                      0.006
             Single                   75 (90.4)      50 (73.5)
             Multiple                  8 (9.6)       18 (26.5)
             Hemoglobin             124 (116 – 132)  124 (117 – 130)  0.809
            Calcification, (%)                                    0.058
             Absent                   74 (89.2)      66 (97.1)
             Present                  9 (10.8)        2 (2.9)
            Solid component, (%)                                  0.611
             Absent                   81 (97.6)      66 (97.1)
             Present                   2 (2.4)        2 (2.9)


            Volume 9 Issue 2 (2025)                        135                              doi: 10.36922/ejmo.8507
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