Page 202 - EJMO-9-2
P. 202

Eurasian Journal of
            Medicine and Oncology                                                Vitamin D and HNC: Causal association






































                             Figure 4. Scatterplot for the causal relationship between Vitamin D levels and head-and-neck cancer
































                             Figure 5. Leave-one-out analysis for the association of Vitamin D levels with head-and-neck cancer

            risk. Furthermore, MVMR analysis revealed that this   A nested case–control study was conducted among male
            causal relationship was independent of the effects of ever-  smokers in Finland to examine the relationship between
            smoking and alcohol consumption.                   blood 25(OH)D levels and HNC risk in the context of alpha-
              Previous studies on whether Vitamin D levels affect   tocopherol and beta-carotene. The study included 340
            HNC occurrences have revealed inconsistent results. 5,12-15    HNC cases and 340 controls and used conditional logistic


            Volume 9 Issue 2 (2025)                        194                              doi: 10.36922/ejmo.7099
   197   198   199   200   201   202   203   204   205   206   207