Page 66 - EJMO-9-2

Eurasian Journal of
Medicine and Oncology TCM regulates gut microbiota in pediatric MP pneumonia

doi: 10.16766/j.cnki.issn.1674-4152.003879 intestinal flora and serum interferon-γ and interleukin-4
levels in children with Mycoplasma pneumoniae. West Med.
32. Canavan TN, Mathes EF, Frieden I, Shinkai K. Mycoplasma
pneumoniae-induced rash and mucositis as a syndrome 2021;33(11):1687-1690.
distinct from Stevens-Johnson syndrome and erythema 44. Liu S, Xing Y, Yang Y, Pei X, Guan L. Traditional Chinese
multiforme: A systematic review. J Am Acad Dermatol. medicine nursing programme for children with Mycoplasma
2015;72(2):239-245. pneumoniae Pneumoniae in Beijing (Version 2023). Beijing
Tradit Chin Med. 2023;42(12):1302-1306.
doi: 10.1016/j.jaad.2014.06.026
doi: 10.16025/j.1674-1307.2023.12.005
33. Song Z, Jia G, Luo G, Han C, Zhang B, Wang X. Global
research trends of Mycoplasma pneumoniae pneumonia 45. Yang M, Meng F, Gao M, Cheng G, Wang X. Cytokine
in children: A bibliometric analysis. Front Pediatr. signatures associate with disease severity in children
2023;11:1306234. with Mycoplasma pneumoniae pneumonia. Sci
Rep. 2019;9(1):17853.
doi: 10.3389/fped.2023.1306234
doi: 10.1038/s41598-019-54313-9
34. Esposito S, Cavagna R, Bosis S, Droghetti R, Faelli N,
Principi N. Emerging role of Mycoplasma pneumoniae in 46. Geginat J, Paroni M, Maglie S, et al. Plasticity of human CD4
children with acute pharyngitis. Eur J Clin Microbiol Infect T cell subsets. Front Immunol. 2014;5:630.
Dis. 2002;21(8):607-610.
doi: 10.3389/fimmu.2014.00630
doi: 10.1007/s10096-002-0780-7
47. Tanaka T, Narazaki M, Kishimoto T. IL-6 in inflammation,
35. Guo B, Qiao J, Pang X, Li H, Hou Y, Tian J. Correlation immunity, and disease. Cold Spring Harb Perspect Biol.
analysis of 23S rRNA gene locus mutations with antibiotic 2014;6(10):a016295.
resistance in Mycoplasma pneumoniae pneumonia in doi: 10.1101/cshperspect.a016295
children. Chinese J Hyg Inspect. 2022;32(15):1836-1839.
48. Rose-John S. Interleukin-6 family cytokines. Cold Spring
36. Gu Y, Yang F, Ye J, Hua L, Li J, Ding GD. Macrolide resistance Harb Perspect Biol. 2018;10(2):a028415.
and clinical management of Mycoplasma pneumoniae in
hospitalised children. J Clin Paediatr. 2024;42(3):182- doi: 10.1101/cshperspect.a028415
186+192. 49. Wu X, Li H, Sun D, Han Y, Li X. Network pharmacological
37. Xue H. An investigation of the progress of drug treatment mechanism of Mycoplasma pneumoniae and bronchial
of paediatric Mycoplasma pneumoniae pneumonia. China asthma by “different diseases treated together” with Ma Xing
Prescrip Drugs. 2020;18(1):12-13. Shi Gan Tang. Tianjin Tradit Chin Med. 2023;40(7):916-924.
38. Chen G. Feasibility analysis of macrolide antibiotics 50. Wang Y, Peng H, Wang A, Zhang W, Bai C, Li P. Molecular
combined with traditional Chinese medicine soup in the mechanism of ephedra apricot shikimantang in the treatment
treatment of paediatric mycoplasma pneumonia. China of pneumonia revealed based on transcriptional profiling
Rural Health. 2019;11(24):41+43. and structural data of traditional Chinese medicines. Chin
J Exp Formulas.1-11.
39. Jiang Z, Li S, Zhu C, Zhou R, Leung PHM. Mycoplasma
pneumoniae infections: Pathogenesis and vaccine doi: 10.13422/j.cnki.syfjx.20250219
development. Pathogens. 2021;10(2):119. 51. Wang QY, Tao LM. Effect of Yin Qiao San combined with
doi: 10.3390/pathogens10020119 the addition and subtraction formula of Ma Xing Shi Gan
Tang on Th1/Th2 and Th17/Treg cytokines in paediatric
40. Wang X, Ren Y, Li W. Exploring the relationship between Mycoplasma pneumoniae with wind-heat and lung closure
pneumonia cough and intestinal flora based on “lung and syndrome. Chin Pharm. 2024;27(3):440-446.
intestinal treatment together”. J Chin Med. 2023;38(12):
2493-2498. 52. Li Y, Chen D. Clinical significance and prognostic
assessment value of CXC chemokine ligand 8, nuclear
doi: 10.16368/j.issn.1674-8999.2023.12.399
transcription factor κB, and soluble B7-H3 in children
41. Yuan Yu. Exploring the relationship between intestinal with Mycoplasma pneumoniae pneumonia. J Women’s Child
flora dysbiosis and cellular immunity in children with Health. 2024;3(20):194-199.
bronchopneumonia. China Med Innov. 2021;18(14):67-70.
53. Ma C, Hao X, Gao L, et al. Extracellular vesicles released
42. Shi S, Zhang X, Zhou Y, Tang H, Zhao D, Liu F. from macrophages infected with Mycoplasma pneumoniae
Immunosuppression reduces lung injury caused by stimulate proinflammatory response via the TLR2-NF-κB/
Mycoplasma pneumoniae infection. Sci Rep. 2019;9(1):7147. JNK signaling pathway. Int J Mol Sci. 2023;24(10):8588.
doi: 10.1038/s41598-019-43451-9 doi: 10.3390/ijms24108588
43. Hu Y, Gao G, Li X, Xiang H, Feng Q. Relationship between 54. Thompson S, Pang CY, Sepuru KM, et al. Nitration of

Volume 9 Issue 2 (2025) 58 doi: 10.36922/ejmo.8602