Page 290 - EJMO-9-3

Eurasian Journal of
Medicine and Oncology Preperitoneal infiltration after laparoscopic cholecystectomy

Table 1. Demographic characteristics of the patient groups
Demographic data TAP block group (n=20) Preperitoneal group (n=20) Test value p‑value
Age (years) 20–60 (42.45±12.37) 20–60 (41.80±10.86) 0.031 0.861
Sex (%)
Female 3 (15.0) 5 (25.0) 0.625 0.429
Male 17 (85.0) 15 (75.0)
Body mass index (kg/m ) 20–26 (23.60±2.04) 20–29 (24.20±2.98) 0.552 0.462
2
ASA classification
ASA1, n (%) 11 (55.0) 13 (65.0) 0.417 0.519
ASA2, n (%) 9 (45.0) 7 (35.0)
Operative time (minutes) 33–51 (42.27±6.43) 34–54 (44.34±7.26) 0.955 0.346
Block duration (minutes) 4–7 (5.90±1.03) 5–8 (6.32±1.14) 1.223 0.229
Note: Data presented as range (mean±standard deviation), unless stated otherwise. Independent sample t-test for mean±standard deviation; Chi-square
test for number (%) or Fisher’s exact test, when appropriate.
Abbreviations: ASA: American Society of Anesthesiologists; TAP: Transversus abdominis plane.

Table 2. Comparison of sleep quality between groups Table 3. Comparison of the Visual Analog Scale between
groups
Group Sleep quality score Test value p‑value
TAP block group 5–9 (7.05±1.23) 0.129 0.721 Visual Analog TAP block Preperitoneal Test p‑value
Scale measurement group (n=20) group (n=20) value
Preperitoneal group 5–10 (7.20±1.40) timepoints
Note: Data presented as range (mean±standard deviation), unless 0-h 1.862 0.572
stated otherwise. Mean±SD 1.45±1.00 1.25±0.79
Abbreviation: TAP: Transversus abdominis plane.
Median (IQR) 2 (0–2) 2 (1–2)
Table 5 shows that the time to the first request for Range 0–3 0–3
analgesia was significantly longer in the TAP block group 2-h 0.958 0.762
compared to the preperitoneal group. Patients in the TAP Mean±SD 2.04±0.82 1.95±0.69
block group required rescue analgesia after an average of Median (IQR) 3 (2–3) 3 (1–3)
14.6 ± 2.52 h, whereas those in the preperitoneal group Range 1–3 1–3
requested it after 7.1 ± 1.02 h (p<0.001). This highly 4-h 1.175 0.386
significant result underscores the prolonged analgesic Mean±SD 2.85±0.59 3.02±0.44
effect of the TAP block, providing extended pain relief Median (IQR) 3 (2–3) 3 (3–4)
and delaying the need for additional pain management Range 1–4 3–4
interventions. In addition, there was a statistically 8-h 2.793 0.027*
significantly higher total dose of analgesia in the pre- Mean±SD 2.90±0.31 3.80±0.41
peritoneal group compared to the TAP block group, Median (IQR) 3 (3–3) 4 (4–5)
with a p<0.05. Narcotics requirement was significantly Range 2–3 3–4
less frequent among the TAP block group (Table 6). In 12-h 2.975 0.019*
addition, the total dose of opioids was significantly lower Mean±SD 3.30±0.57 5.10±0.85
in the TAP block group (Table 7).
Median (IQR) 3 (3–4) 5 (4–6)
4. Discussion Range 2–4 3–7
24-h 1.376 0.291
Cholecystectomy is one of the most commonly performed
surgical procedures. The laparoscopic approach is becoming Mean±SD 3.50±1.00 4.05±0.89
progressively popular due to its earlier recovery and shorter Median (IQR) 4 (3–4) 5 (3–5)
hospital stay, as well as its reduced post-operative pain and Range 1–5 2–6
morbidity compared to open cholecystectomy surgery. 2 Note: Statistical analysis conducted using the Mann–Whitney test for
non-parametric data. *indicates statistical significance at p<0.05.
During laparoscopic cholecystectomy, various Abbreviations: IQR: Interquartile; SD: Standard deviation;
perioperative causes, including pneumo-peritoneum, TAP: Transversus abdominis plane.

Volume 9 Issue 3 (2025) 282 doi: 10.36922/EJMO025180164