Page 100 - GPD-1-2
P. 100

Gene & Protein in Disease                                                  Structure and function of USP7



            Conflict of interest                                  deubiquitinylation and localization of PTEN are regulated
                                                                  by a HAUSP-PML network. Nature, 455(7214): 813–817.
            The authors declare that they have no competing interests.
                                                                  https://doi.org/10.1038/nature07290
            Author contributions                               11.  Jacq X, Kemp M, Martin NM, et al., 2013, Deubiquitylating

            Conceptualization: Xinliang Mao                       enzymes and DNA damage response pathways. Cell Biochem
                                                                  Biophys, 67(1): 25–43.
            Supervision: Xinliang Mao
            Writing – original draft: Yuanming He, Yueya Zhong     https://doi.org/10.1007/s12013-013-9635-3
            Writing –  review & editing: Yuanming He, Yiqian Wang,   12.  Mathien S, Déléris P, Soulez M, et al., 2017, Deubiquitinating
                    Xinliang Mao                                  enzyme USP20 regulates extracellular signal-regulated
                                                                  kinase 3 stability and biological activity. Mol Cell Biol, 37(9):
            References                                            e00432–16.

            1.   Nakamura N, 2018, Ubiquitin system. Int J Mol Sci, 19(4):      https://doi.org/10.1128/MCB.00432-16
               1080.
                                                               13.  Kim SY, Baek KH, 2019, TGF-β signaling pathway mediated
               https://doi.org/10.3390/ijms19041080               by deubiquitinating enzymes. Cell Mol Life Sci, 76(4): 653–665.
            2.   Hershko  A, Heller  H, Elias S,  et al., 1983,  Components      https://doi.org/10.1007/s00018-018-2949-y
               of ubiquitin-protein ligase system. Resolution, affinity   14.  Sun T, Liu Z, Yang Q, 2020, The role of ubiquitination and
               purification, and role in protein breakdown. J Biol Chem,   deubiquitination in cancer metabolism. Mol Cancer, 19(1): 146.
               258(13): 8206–8214.
                                                               15.  Wang Q, Ma S, Song N, et al., 2016, Stabilization of histone
            3.   Xu  P,  Duong  DM,  Seyfried NT,  et al.,  2009,  Quantitative   demethylase PHF8 by USP7 promotes breast carcinogenesis.
               proteomics reveals the function of unconventional ubiquitin   J Clin Invest, 126(6): 2205–2220.
               chains in proteasomal degradation. Cell, 137(1): 133–145.
                                                                  https://doi.org/10.1172/JCI85747
               https://doi.org/10.1016/j.cell.2009.01.041
                                                               16.  Zhan M, Sun X, Liu J,  et al., 2017, Usp7 promotes
            4.   Nijman SM, Luna-Vargas MP, Velds A,  et al., 2005, A   medulloblastoma cell  survival  and metastasis by  activating
               genomic and functional inventory of deubiquitinating   Shh pathway. Biochem Biophys Res Commun, 484(2): 429–434.
               enzymes. Cell, 123(5): 773–786.
                                                                  https://doi.org/10.1016/j.bbrc.2017.01.144
               https://doi.org/10.1016/j.cell.2005.11.007
                                                               17.  Jin Q, Martinez CA, Arcipowski KM,  et al., 2019, USP7
            5.   Poondla N, Chandrasekaran AP, Kim KS,  et al., 2019,   cooperates with NOTCH1 to drive the oncogenic
               Deubiquitinating enzymes as cancer biomarkers: New   transcriptional program in T-cell leukemia. Clin Cancer Res,
               therapeutic opportunities? BMB Rep, 52(3): 181–189.   25(1): 222–239.
               https://doi.org/10.5483/BMBRep.2019.52.3.048       https://doi.org/10.1158/1078-0432.CCR-18-1740
            6.   Pozhidaeva A, Bezsonova I, 2019, USP7: Structure, substrate   18.  Wang M, Zhang Y, Wang T, et al., 2017, The USP7 inhibitor
               specificity, and inhibition. DNA Repair (Amst), 76: 30–39.   P5091 induces cell death in ovarian cancers with different
               https://doi.org/10.1016/j.dnarep.2019.02.005       P53 status. Cell Physiol Biochem, 43(5): 1755–1766.
            7.   Wang S, Juan J, Zhang Z,  et al., 2017, Inhibition of the      https://doi.org/10.1159/000484062
               deubiquitinase USP5 leads to c-Maf protein degradation   19.  Zhao GY, Lin ZW, Lu CL, et al., 2015, USP7 overexpression
               and myeloma cell apoptosis. Cell Death Dis, 8(9): e3058.   predicts a poor prognosis in lung squamous cell carcinoma
               https://doi.org/10.1038/cddis.2017.450             and large cell carcinoma. Tumour Biol, 36(3): 1721–1729.
            8.   Zhang C, Chen Y, Gan X, et al., 2017, SAK-HV decreases      https://doi.org/10.1007/s13277-014-2773-4
               the self-ubiquitination of MEKK1 to promote macrophage   20.  He Y, Wang S, Tong J, et al., 2020, The deubiquitinase USP7
               proliferation via MAPK/ERK and JNK Pathways. Int J Mol   stabilizes maf proteins to promote myeloma cell survival.
               Sci, 18(4): 835.                                   J Biol Chem, 295(7): 2084–2096.
               https://doi.org/10.3390/ijms18040835               https://doi.org/10.1074/jbc.RA119.010724
            9.   Lork M, Verhelst K, Beyaert R, 2017, CYLD, A20 and OTULIN   21.  Li M, Brooks CL, Kon N,  et al., 2004, A dynamic role of
               deubiquitinases in NF-κB signaling and cell death: So similar,   HAUSP in the p53-Mdm2 pathway. Mol Cell, 13(6): 879–886.
               yet so different. Cell Death Differ, 24(7): 1172–1183.
                                                                  https://doi.org/10.1016/s1097-2765(04)00157-1
               https://doi.org/10.1038/cdd.2017.46
                                                               22.  Nicklas S, Hillje AL, Okawa S, et al., 2019, A complex of
            10.  Song MS, Salmena L, Carracedo A,  et al., 2008, The   the ubiquitin ligase TRIM32 and the deubiquitinase USP7


            Volume 1 Issue 2 (2022)                         10                     https://doi.org/10.36922/gpd.v1i2.118
   95   96   97   98   99   100   101   102   103   104   105