Page 120 - GPD-1-2

Gene & Protein in Disease Exosomes connect periodontitis and systemic diseases

https://doi.org/10.14202/vetworld.2018.627-635 for exosome isolation and analysis. Cells, 8(7): 727.
45. Arbab M, Tahir S, Niazi MK, et al., 2017, TNF-α genetic https://doi.org/10.3390/cells8070727
predisposition and higher expression of inflammatory 55. Mashouri L, Yousefi H, Aref AR, et al., 2019, Exosomes:
pathway components in keratoconus. Invest Ophthalmol Vis Composition, biogenesis, and mechanisms in cancer
Sci, 58(9): 3481–3487. metastasis and drug resistance. Mol Cancer, 18(1): 75.
https://doi.org/10.1167/iovs.16-21400 https://doi.org/10.1186/s12943-019-0991-5
46. Majumder P, Thou K, Bhattacharya M, et al., 2018, 56. Mathivanan S, Ji H, Simpson RJ, 2010, Exosomes:
Association of tumor necrosis factor-α (TNF-α) gene Extracellular organelles important in intercellular
promoter polymorphisms with aggressive and chronic communication. J Proteom, 73(10): 1907–1920.
periodontitis in the Eastern Indian population. Biosci Rep,
38(4): BSR20171212. https://doi.org/10.1016/j.jprot.2010.06.006
https://doi.org/10.1042/bsr20171212 57. Kalluri R, LeBleu VS, 2020, The biology, function, and
biomedical applications of exosomes. Science, 367(6478):
47. Seutter S, Winfield J, Esbitt A, et al., 2020, Interleukin 1β eaau6977.
and prostaglandin E2 affect expression of DNA methylating
and demethylating enzymes in human gingival fibroblasts. https://doi.org/10.1126/science.aau6977
Int immunopharmacol, 78: 105920. 58. Emanueli C, Shearn AI, Angelini GD, et al., 2015, Exosomes
https://doi.org/10.1016/j.intimp.2019.105920 and exosomal miRNAs in cardiovascular protection and
repair. Vascul Pharmacol, 71: 24–30.
48. Grga D, Dzeletović B, Damjanov M, et al., 2013, Prostaglandin
E2 in apical tissue fluid and postoperative pain in intact and https://doi.org/10.1016/j.vph.2015.02.008
teeth with large restorations in two endodontic treatment 59. Cai J, Wu J, Wang J, et al., 2020, Extracellular vesicles derived
visits. Srp Arh Celok Lek, 141(1–2): 17–21. from different sources of mesenchymal stem cells: Therapeutic
effects and translational potential. Cell Biosci, 10: 69.
https://doi.org/10.2298/sarh1302017g
https://doi.org/10.1186/s13578-020-00427-x
49. Offenbacher S, Heasman PA, Collins JG, 1993, Modulation
of host PGE2 secretion as a determinant of periodontal 60. Liang B, He X, Zhao YX, et al., 2020, Advances in exosomes
disease expression. J Periodontol, 64(5 Suppl): 432–444. derived from different cell sources and cardiovascular
diseases. Biomed Res Int, 2020: 7298687.
https://doi.org/10.1902/jop.1993.64.5.432
https://doi.org/10.1155/2020/7298687
50. Oduncuoglu BF, Kayar NA, Haliloglu S, et al, 2018, Effects
of a cyclic NSAID regimen on levels of gingival crevicular 61. Gurunathan S, Kang MH, Jeyaraj M, et al., 2019, Review of the
fluid prostaglandin E(2)and Interleukin-1β: A 6-month isolation, characterization, biological function, and multifarious
randomized controlled clinical trial. Niger J Clin Pract, therapeutic approaches of exosomes. Cells, 8(4): 307.
21(5): 658–666. https://doi.org/10.3390/cells10020462
https://doi.org/10.4103/njcp.njcp_221_17 62. Xunian Z, Kalluri R, 2020, Biology and therapeutic potential
51. Cox SW, Eley BM, Kiili M, et al., 2006, Collagen degradation of mesenchymal stem cell-derived exosomes. Cancer Sci,
by interleukin-1beta-stimulated gingival fibroblasts is 111(9): 3100–3110.
accompanied by release and activation of multiple matrix https://doi.org/10.1111/cas.14563
metalloproteinases and cysteine proteinases. Oral Dis, 12(1):
34–40. 63. Milane L, Singh A, Mattheolabakis G, et al., 2015,
Exosome mediated communication within the tumor
https://doi.org/10.1111/j.1601-0825.2005.01153.x microenvironment. J Control Release, 219: 278–294.
52. Álvares PR, Arruda JA, Silva LP, et al., 2017, https://doi.org/10.1016/j.jconrel.2015.06.029
Immunohistochemical expression of TGF-β1 and MMP-9
in periapical lesions. Braz Oral Res, 31: e51. 64. Yáñez-Mó M, Siljander PR, Andreu Z, et al., 2015, Biological
properties of extracellular vesicles and their physiological
https://doi.org/10.1590/1807-3107bor-2017.vol31.0051 functions. J Extracell Vesicles, 4: 27066.
53. Cocucci E, Meldolesi J, 2015, Ectosomes and exosomes: 65. van Niel GV, D’Angelo G, Raposo G. Shedding light on the
Shedding the confusion between extracellular vesicles. cell biology of extracellular vesicles. Nat Rev Mol Cell Biol,
Trends Cell Biol, 25(6): 364–372. 19: 213–228.
https://doi.org/10.1016/j.tcb.2015.01.004 https://doi.org/10.1038/nrm.2017.125
54. Doyle LM, Wang MZ, 2019, Overview of extracellular 66. Record M, Silvente-Poirot S, Poirot M, et al., 2018,
vesicles, their origin, composition, purpose, and methods Extracellular vesicles: Lipids as key components of their

Volume 1 Issue 2 (2022) 13 https://doi.org/10.36922/gpd.v1i2.99