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Gene & Protein in Disease Exosomes connect periodontitis and systemic diseases
Province, China (No. 21A320004), the Foundation of between periodontitis and chronic kidney disease.
National Health Commission of Henan Province, China Periodontol 2000, 89(1): 114–124.
(No. Wjlx2020017), and the Foundation of Science & https://doi.org/10.1111/prd.12431
Technology Department of Luoyang City, Henan Province, 9. Liccardo D, Marzano F, Carraturo F, et al., 2020, Potential
China (No. 2101065A).
bidirectional relationship between periodontitis and
Conflict of interest Alzheimer’s disease. Front Physiol, 11: 683.
https://doi.org/10.3389/fphys.2020.00683
None.
10. Werber T, Bata Z, Vaszine ES, et al., 2021, The association of
Author contributions periodontitis and Alzheimer’s disease: How to hit two birds
with one stone. J Alzheimers Dis, 84(1): 1–21.
Data curation: Jing Xu, Xin Chang, Huixin Zhang,
Mengying Si, Huiying Su, Lilan Cao https://doi.org/10.3233/jad-210491
Funding acquisition: Yuankun Zhai 11. Leira Y, Seoane J, Blanco M, et al., 2017, Association between
Investigation: Mengying Si periodontitis and ischemic stroke: A systematic review and
Project administration: Yuankun Zhai meta-analysis. Eur J Epidemiol, 32(1): 43–53.
Supervision: Yuankun Zhai https://doi.org/10.1007/s10654-016-0170-6
Visualization: Jing Xu, Huixin Zhang 12. Bengtsson VW, Persson GR, Berglund JS, et al., 2021,
Writing – original draft: Jing Xu, Xin Chang Periodontitis related to cardiovascular events and mortality:
Writing – review and editing: Yingying Li, Yuankun Zhai A long-time longitudinal study. Clin Oral Investig, 25(6):
4085–4095.
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Volume 1 Issue 2 (2022) 11 https://doi.org/10.36922/gpd.v1i2.99

