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Gene & Protein in Disease                                                              MOR in cancer



            92.  Koodie L, Ramakrishnan S, Roy S, 2010, Morphine   immune function via the JAK3/STAT5 pathway.  Pain Res
               suppresses tumor angiogenesis through a HIF-1alpha/  Manag, 2022: 9364365.
               p38MAPK pathway. Am J Pathol, 177(2): 984–997.
                                                                  https://doi.org/10.1155/2022/9364365
               https://doi.org/10.2353/ajpath.2010.090621      105. Zielińska M, Szymaszkiewicz A, Jacenik D,  et  al., 2020,
            93.  Singleton PA, Mirzapoiazova T, Hasina R,  et al., 2014,   Cyclic derivative of morphiceptin Dmt-cyclo-(D-Lys-Phe-
               Increased µ-opioid receptor expression in metastatic lung   D-Pro-Asp)-NH2(P-317), a mixed agonist of MOP and
               cancer. Br J Anaesth, 113 Suppl 1: i103–i108.      KOP opioid receptors, exerts anti-inflammatory and anti-
                                                                  tumor activity in colitis and colitis-associated colorectal
               https://doi.org/10.1093/bja/aeu165
                                                                  cancer in mice. Eur J Pharmacol, 885: 173463.
            94.  Bimonte  S,  Barbieri  A,  Rea  D,  et al.,  2015,  Morphine
               promotes tumor angiogenesis and increases breast cancer      https://doi.org/10.1016/j.ejphar.2020.173463
               progression. Biomed Res Int, 2015: 161508.      106. Boehncke S, Hardt K, Schadendorf  D,  et al., 2011,
                                                                  Endogenous µ-opioid peptides modulate immune response
               https://doi.org/10.1155/2015/161508
                                                                  towards malignant melanoma. Exp Dermatol, 20(1): 24–28.
            95.  Murohara T, Asahara T, 2002, Nitric oxide and angiogenesis
               in cardiovascular disease.  Antioxid Redox Signal, 4(5):      https://doi.org/10.1111/j.1600-0625.2010.01158.x
               825–831.                                        107. Coluzzi  F,  Rullo  L,  Scerpa  MS,  et al.,  2022,  Current  and
                                                                  future  therapeutic  options in  pain management: Multi-
               https://doi.org/10.1089/152308602760598981
                                                                  mechanistic opioids involving both MOR and NOP receptor
            96.  Dimmeler S, Zeiher AM, 2000, Endothelial cell apoptosis in   activation. CNS Drugs, 36(6): 617–632.
               angiogenesis and vessel regression. Circ Res, 87(6): 434–439.
                                                                  https://doi.org/10.1007/s40263-022-00924-2
            97.  Hsiao PN, Chang MC, Cheng WF, et al., 2009, Morphine   108. Gorur A, Patiño M, Shi T,  et al., 2021, Low doses of
               induces apoptosis of human endothelial cells through nitric
               oxide and reactive oxygen species pathways.  Toxicology,   methylnaltrexone inhibits head and neck squamous cell
               256(1–2): 83–91.                                   carcinoma growth  in vitro and  in vivo by acting on the
                                                                  mu-opioid receptor. J Cell Physiol, 236(11): 7698–7710.
               https://doi.org/10.1016/j.tox.2008.11.015
                                                                  https://doi.org/10.1002/jcp.30421
            98.  Ziche M, Morbidelli L, 2000, Nitric oxide and angiogenesis.   109. Singleton PA, Moss J, 2010, Effect of perioperative opioids
               J Neurooncol, 50(1–2): 139–148.
                                                                  on cancer recurrence: A  hypothesis.  Future Oncol, 6(8):
               https://doi.org/10.1023/a:1006431309841            1237–1242.
            99.  Kenny  PA, Lee  GY,  Bissell  MJ, Targeting  the  tumor      https://doi.org/10.2217/fon.10.99
               microenvironment. Front Biosci, 12: 3468–3474.
                                                               110. da Silva JL, Dos Santos AL, Nunes NC, de Moraes Lino
               https://doi.org/10.2741/2327                       da Silva F, et al., 2019, Cancer immunotherapy: The art of
            100. Sung SY, Hsieh CL, Wu D,  et al., 2007, Tumor    targeting  the  tumor  immune  microenvironment.  Cancer
               microenvironment promotes cancer progression, metastasis,   Chemother Pharmacol, 84(4): 227–240.
               and therapeutic resistance. Curr Probl Cancer, 31(2): 36–100.     https://doi.org/10.1007/s00280-019-03894-3
               https://doi.org10.1016/j.currproblcancer.2006.12.002  111. Esfahani K, Roudaia L, Buhlaiga N, et al., 2020, A review of
                                                                  cancer immunotherapy: From the past, to the present, to the
            101. Fang H, Declerck YA, 2013, Targeting the tumor
               microenvironment: From understanding pathways to   future. Curr Oncol, 27: S87–S97.
               effective clinical trials. Cancer Res, 73(16): 4965–4977.     https://doi.org/10.3747/co.27.5223
               https://doi.org/10.1158/0008-5472.CAN-13-0661   112. Emens LA, 2018, Breast cancer immunotherapy: Facts and
                                                                  hopes. Clin Cancer Res, 24(3): 511–520.
            102. Liang X, Liu R, Chen C, et al., 2016, Opioid system modulates
               the immune function: A review. Transl Perioper Pain Med,      https://doi.org/10.1158/1078-0432.CCR-16-3001
               1(1): 5–13.
                                                               113. Chen G, Kim YH, Li H, et al., 2017, PD-L1 inhibits acute
            103. Koodie L, Yuan H, Pumper JA,  et al., 2014, Morphine   and chronic pain by suppressing nociceptive neuron activity
               inhibits migration of tumor-infiltrating leukocytes and   via PD-1. Nat Neurosci, 20(7): 917–926.
               suppresses angiogenesis associated with tumor growth in      https://doi.org/10.1038/nn.4571
               mice. Am J Pathol, 184(4): 1073–1084.
                                                               114. McLaughlin PJ, Verderame MF, Hankins JL,  et al., 2007,
               https://doi.org/10.1016/j.ajpath.2013.12.019
                                                                  Overexpression of the opioid growth factor receptor
            104. Jiang Y, Li T, Qian Y, et al., 2022, Morphine in combination   downregulates  cell  proliferation  of  human  squamous
               with ketamine improves cervical cancer pain and suppresses   carcinoma cells of the head and neck. Int J Mol Med, 19(3):


            Volume 2 Issue 2 (2023)                         17                        https://doi.org/10.36922/gpd.282
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