Page 19 - GPD-3-2
P. 19
Gene & Protein in Disease lncRNAs in trained immunity
differentiation. Science. 2014;344(6181):310-313. modulator of macrophage M2 polarization. Cancer Immunol
Res. 2019;7(2):292-305.
doi: 10.1126/science.1251456
doi: 10.1158/2326-6066.CIR-18-0145
33. Xin J, Li J, Feng Y, Wang L, Zhang Y, Yang R. Downregulation
of long noncoding RNA HOTAIRM1 promotes monocyte/ 43. Yang C, Shen C, Feng T, Li H. Noncoding RNA in NK cells.
dendritic cell differentiation through competitively binding to J Leukoc Biol. 2019;105(1):63-71.
endogenous miR-3960. Onco Targets Ther. 2017;10:1307-1315.
doi: 10.1002/JLB.1RU0518-197RR
doi: 10.2147/OTT.S124201
44. Sun JC, Madera S, Bezman NA, Beilke JN, Kaplan MH,
34. Zhang M, Zheng Y, Sun Y, et al. Knockdown of NEAT1 Lanier LL. Proinflammatory cytokine signaling required
induces tolerogenic phenotype in dendritic cells by for the generation of natural killer cell memory. J Exp Med.
inhibiting activation of NLRP3 inflammasome. Theranostics. 2012;209(5):947-954.
2019;9(12):3425-3442.
doi: 10.1084/jem.20111760
doi: 10.7150/thno.33178
45. O’Leary JG, Goodarzi M, Drayton DL, Von Andrian UH.
35. Wu J, Li S, Zheng Y, et al. Silencing of lncRNA NEAT1 T cell-and B cell-independent adaptive immunity mediated
induces tolerogenic dendritic cells and immune tolerance by natural killer cells. Nat Immunol. 2006;7(5):507-516.
in heart transplantation. J. Immunol. 2017;198(1_ doi: 10.1038/ni1332
Supplement):82.27-82.27.
46. Sun JC, Beilke JN, Lanier LL. Adaptive immune features of
doi: 10.4049/jimmunol.198.Supp.82.27
natural killer cells. Nature. 2009;457(7229):557-561.
36. Wu J, Zhang H, Zheng Y, et al. The long noncoding RNA
MALAT1 induces tolerogenic dendritic cells and regulatory doi: 10.1038/nature07665
T cells via miR155/dendritic cell-specific intercellular 47. Mowel WK, McCright SJ, Kotzin JJ, et al. Group 1 innate
adhesion molecule-3 grabbing nonintegrin/IL10 axis. Front lymphoid cell lineage identity is determined by a cis-
Immunol. 2018;9:1847. regulatory element marked by a long non-coding RNA.
Immunity. 2017;47(3):435-449.e8.
doi: 10.3389/fimmu.2018.01847
doi: 10.1016/j.immuni.2017.08.012
37. Cai Z, Zhang C, Kotzin JJ, Williams A, Henao-Mejia J,
Kapur R. Role of lncRNA Morrbid in PTPN11(Shp2)E76K- 48. Fang P, Xiang L, Chen W, et al. LncRNA GAS5 enhanced the
driven juvenile myelomonocytic leukemia. Blood Adv. killing effect of NK cell on liver cancer through regulating
2020;4(14):3246-3251. miR-544/RUNX3. Innate Immun. 2019;25(2):99-109.
doi: 10.1182/bloodadvances.2020002123 doi: 10.1177/1753425919827632
38. Ye Y, Xu Y, Lai Y, et al. Long non-coding RNA cox-2 prevents 49. Guttman M, Amit I, Garber M, et al. Chromatin signature
immune evasion and metastasis of hepatocellular carcinoma reveals over a thousand highly conserved large non-coding
by altering M1/M2 macrophage polarization. J Cell Biochem. RNAs in mammals. Nature. 2009;458(7235):223-227.
2018;119(3):2951-2963. doi: 10.1038/nature07672
doi: 10.1002/jcb.26509
50. Carpenter S, Aiello D, Atianand MK, et al. A long noncoding
39. Tian X, Wu Y, Yang Y, et al. Long noncoding RNA RNA mediates both activation and repression of immune
LINC00662 promotes M2 macrophage polarization and response genes. Science. 2013;341(6147):789-92.
hepatocellular carcinoma progression via activating Wnt/β- doi: 10.1126/science.1240925
catenin signaling. Mol Oncol. 2020;14(2):462-483.
51. Morchikh M, Cribier A, Raffel R, et al. HEXIM1 and NEAT1
doi: 10.1002/1878-0261.12606 Long non-coding RNA form a multi-subunit complex that
40. Liang Y, Song X, Li Y, et al. LncRNA BCRT1 promotes breast regulates dna-mediated innate immune response. Mol Cell.
cancer progression by targeting miR-1303/PTBP3 axis. Mol 2017;67(3):387-399.e5.
Cancer. 2020;19(1):85.
doi: 10.1016/j.molcel.2017.06.020
doi: 10.1186/s12943-020-01206-5
52. Wang Y, Wang P, Zhang Y, et al. Decreased expression of
41. Liu D, Wei Y, Liu Y, Wu T, Hu J, Lu H. The Long non- the host long-noncoding RNA-GM facilitates viral escape by
coding RNA NEAT1/miR-224-5p/IL-33 axis modulates inhibiting the kinase activity TBK1 via S-glutathionylation.
macrophage M2a polarization and A1 astrocyte activation. Immunity. 2020;53(6):1168-1181.e7.
Mol Neurobiol. 2021;58(9):4506-4519.
doi: 10.1016/j.immuni.2020.11.010
doi: 10.1007/s12035-021-02405-x
53. Biswas S, Thomas AA, Chen S, et al. MALAT1: An epigenetic
42. Cao J, Dong R, Jiang L, et al. LncRNA-MM2P identified as a regulator of inflammation in diabetic retinopathy. Sci
Volume 3 Issue 2 (2024) 13 doi: 10.36922/gpd.2791

