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Gene & Protein in Disease                                         Comprehensive analysis of ZNF521/Zfp521



            18.  Ohkubo N, Aoto M, Kon K, Mitsuda N. Lack of zinc finger   prognostic markers for muscle-invasive bladder urothelial
               protein 521 upregulates dopamine β-hydroxylase expression   carcinoma by weighted gene co-expression network analysis.
               in the mouse brain, leading to abnormal behavior. Life Sci.   Pathol Oncol Res. 2020;26(2):1063-1072.
               2019;231:116559.
                                                                  doi: 10.1007/s12253-019-00657-6
               doi: 10.1016/j.lfs.2019.116559                  29.  Zhang Y, Xu S, Chen Z, et al. Zfp521 SUMOylation facilities
            19.  Correa D, Hesse E, Seriwatanachai D,  et al. Zfp521 is a   erythroid hematopoietic reconstitution under stress. Biosci
               target gene and key effector of parathyroid hormone-related   Biotechnol Biochem. 2020;84(5):943-953.
               peptide signaling in growth plate chondrocytes.  Dev Cell.      doi: 10.1080/09168451.2019.1703639
               2010;19(4):533-546.
                                                               30.  Chiarella E, Aloisio A, Scicchitano S, et al. ZNF521 represses
               doi: 10.1016/j.devcel.2010.09.008                  osteoblastic differentiation in human adipose-derived stem
            20.  Behrouznezhad F, Ejeian F, Emadi-Baygi M, Nikpour P, Nasr-  cells. Int J Mol Sci. 2018;19(12):4095.
               Esfahani MH. Hypothesis: A  challenge of overexpression      doi: 10.3390/ijms19124095
               Zfp521 in neural tendency of derived dental pulp stem cells.
               Cell J. 2019;21(1):99-102.                      31.  Bond HM, Mesuraca M, Carbone E, et al. Early hematopoietic
                                                                  zinc finger protein (EHZF), the human homolog to mouse
               doi: 10.22074/cellj.2019.5600                      Evi3, is highly expressed in primitive human hematopoietic
            21.  Kamiya D, Banno S, Sasai N,  et al. Intrinsic transition of   cells. Blood. 2004;103(6):2062-2070.
               embryonic stem-cell differentiation into neural progenitors.      doi: 10.1182/blood-2003-07-2388
               Nature. 2011;470(7335):503-509.
                                                               32.  Wang R, Wang Q. Identification and external validation of a
               doi: 10.1038/nature09726                           transcription factor-related prognostic signature in pediatric
            22.  Hashemi M-S, Esfahani AK, Peymani M,  et al. Zinc   neuroblastoma. J Oncol. 2021;2021:1370451.
               finger protein 521 overexpression increased transcript      doi: 10.1155/2021/1370451
               levels  of  Fndc5  in  mouse  embryonic  stem  cells.  J  Biosci.
               2016;41(1):69-76.                               33.  Chiarella E, Aloisio A, Codispoti B, et al. ZNF521 has an
                                                                  inhibitory effect on the adipogenic differentiation of human
               doi: 10.1007/s12038-015-9578-5                     adipose-derived mesenchymal stem cells.  Stem Cell Rev
            23.  Matsubara  E,  Sakai  I,  Yamanouchi  J,  et al.  The  role  of   Rep. 2018;14(6):901-914.
               zinc finger protein 521/Early hematopoietic zinc finger      doi: 10.1007/s12015-018-9830-0
               protein in erythroid cell differentiation.  J  Biol  Chem.
               2009;284(6):3480-3487.                          34.  Saenz-de-Juano MD, Ivanova E, Billooye K, et al. Genome-
                                                                  wide assessment of DNA methylation in mouse oocytes
               doi: 10.1074/jbc.M805874200                        reveals effects associated with in vitro growth, superovulation,
            24.  Hesse E, Saito H, Kiviranta R, et al. Zfp521 controls bone   and sexual maturity. Clin Epigenetics. 2019;11(1):197.
               mass by HDAC3-dependent attenuation of Runx2 activity.      doi: 10.1186/s13148-019-0794-y
               J Cell Biol. 2010;191(7):1271-1283.
                                                               35.  Chen YC, Hsiao CJ, Jung CC,  et al. Performance metrics
               doi: 10.1083/jcb.201009107                         for selecting single nucleotide polymorphisms in late-onset
            25.  Kiviranta R, Baron R. Braking with 30 fingers: ZNF521   Alzheimer’s disease. Sci Rep. 2016;6:36155.
               holds on Ebf1-dependent B-cell development.  Cell Cycle.      doi: 10.1038/srep36155
               2011;10(18):3054.
                                                               36.  Garrison BS, Rybak AP, Beerman I, et al. ZFP521 regulates
               doi: 10.4161/cc.10.18.16999                        murine hematopoietic stem cell function and facilitates
            26.  Huan C, Xiaoxu C, Xifang R. Zinc finger protein 521,   MLL-AF9 leukemogenesis in mouse and human cells. Blood.
               negatively regulated by MicroRNA-204-5p, promotes   2017;130(5):619-624.
               proliferation, motility and invasion of gastric cancer cells.      doi: 10.1182/blood-2016-09-738591
               Technol Cancer Res Treat. 2019;18:1533033819874783.
                                                               37.  Li Z, Fu X, Wu W, et al. Zfp521 is essential for the quiescence
               doi: 10.1177/1533033819874783                      and maintenance of adult hematopoietic stem cells under
            27.  Salerno L, Cosentino C, Morrone G, Amato F. Computational   stress. iScience. 2021;24(2):102039.
               modeling  of  a  transcriptional  switch  underlying      doi: 10.1016/j.isci.2021.102039
               B-Lymphocyte lineage commitment of hematopoietic   38.  Sera Y, Yamasaki N, Oda H, et al. Identification of cooperative
               multipotent cells. PLoS One. 2015;10(7):e0132208.
                                                                  genes  for  E2A-PBX1  to  develop  acute  lymphoblastic
               doi: 10.1371/journal.pone.0132208                  leukemia. Cancer Sci. 2016;107(7):890-898.
            28.  Feng Y, Jiang Y, Wen T, Meng F, Shu X. Identifying potential      doi: 10.1111/cas.12945


            Volume 3 Issue 3 (2024)                         11                              doi: 10.36922/gpd.3260
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