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Gene & Protein in Disease Comprehensive analysis of ZNF521/Zfp521

39. Al Dallal S, Wolton K, Hentges KE. Zfp521 promotes B-cell SIAH2 is expressed in adipocyte precursor cells and
viability and cyclin D1 gene expression in a B cell culture interacts with EBF1 and ZFP521 to promote adipogenesis.
system. Leuk Res. 2016;46:10-17. Obesity (Silver Spring). 2020;29(1):98-107.
doi: 10.1016/j.leukres.2016.03.013 doi: 10.1002/oby.23013
40. Boller S, Grosschedl R. The regulatory network of B-cell 51. Addison WN, Fu MM, Yang HX, et al. Direct transcriptional
differentiation: A focused view of early B-cell factor 1 repression of Zfp423 by Zfp521 mediates a bone morphogenic
function. Immunol Rev. 2014;261(1):102-115. protein-dependent osteoblast versus adipocyte lineage
commitment switch. Mol Cell Biol. 2014;34(16):3076-3085.
doi: 10.1111/imr.12206
doi: 10.1128/MCB.00185-14
41. Takai H, van Wijnen AJ, Ogata Y. Induction of chondrogenic
or mesenchymal stem cells from human periodontal 52. Wei PC, Chao A, Peng HH, et al. SOX9 as a predictor for
ligament cells through inhibition of Twist2 or Klf12. J Oral neurogenesis potentiality of amniotic fluid stem cells. Stem
Sci. 2019;61(2):313-320. Cells Transl Med. 2014;3(10):1138-1147.
doi: 10.2334/josnusd.18-0224 doi: 10.5966/sctm.2014-0019
42. Hesslein DG, Fretz JA, Xi Y, et al. Ebf1-dependent 53. Kilroy G, Kirk-Ballard H, Carter LE, Floyd ZE. The ubiquitin
control of the osteoblast and adipocyte lineages. Bone. ligase Siah2 regulates PPARγ activity in adipocytes.
2009;44(4):537-546. Endocrinology. 2012;153(3):1206-1218.
doi: 10.1016/j.bone.2008.11.021 doi: 10.1210/en.2011-1725
43. Rosen ED, Spiegelman BM. PPARgamma: A nuclear 54. Kilroy G, Burk DH, Floyd ZE. Siah2 protein mediates early
regulator of metabolism, differentiation, and cell growth. events in commitment to an adipogenic pathway. J Biol
J Biol Chem. 2001;276(41):37731-37734. Chem. 2016;291(53):27289-27297.
doi: 10.1074/jbc.R100034200 doi: 10.1074/jbc.M116.744672
44. Tseng KY, Lin S. Zinc finger factor 521 enhances adipogenic 55. Wu M, Hesse E, Morvan F, et al. Zfp521 antagonizes Runx2,
differentiation of mouse multipotent cells and human delays osteoblast differentiation in vitro, and promotes bone
bone marrow mesenchymal stem cells. Oncotarget. formation in vivo. Bone. 2009;44(4):528-536.
2015;6(17):14874-14884.
doi: 10.1016/j.bone.2008.11.011
doi: 10.18632/oncotarget.3900
56. Seriwatanachai D, Densmore MJ, Sato T, et al. Deletion
45. Han ZJ, Feng YH, Gu BH, Li YM, Chen H. The post- of Zfp521 rescues the growth plate phenotype in a mouse
translational modification, SUMOylation, and cancer model of Jansen metaphyseal chondrodysplasia. FASEB J.
(Review). Int J Oncol. 2018;52:1081-1094. 2011;25(9):3057-3067.
doi: 10.3892/ijo.2018.4280 doi: 10.1096/fj.11-183277
46. Yamasaki N, Miyazaki K, Nagamachi A, et al. Identification 57. Park SY, Kim JE. Differential gene expression by Osterix
of Zfp521/ZNF521 as a cooperative gene for E2A- knockdown in mouse chondrogenic ATDC5 cells. Gene.
HLF to develop acute B-lineage leukemia. Oncogene. 2013;518(2):368-375.
2010;29(13):1963-1975.
doi: 10.1016/j.gene.2012.12.102
doi: 10.1038/onc.2009.475
58. Zhang W, Chen J, Zhang S, Ouyang HW. Inhibitory function
47. Kang S, Akerblad P, Kiviranta R, et al. Regulation of parathyroid hormone-related protein on chondrocyte
of early adipose commitment by Zfp521. PLoS Biol. hypertrophy: The implication for articular cartilage repair.
2012;10(11):e1001433. Arthritis Res Ther. 2012;14(4):221.
doi: 10.1371/journal.pbio.1001433 doi: 10.1186/ar4025
48. Ganuza M, McKinney-Freeman S. Hematopoietic stem cells 59. Liu TM, Lee EH. Transcriptional regulatory cascades in
under pressure. Curr Opin Hematol. 2017;24(4):314-321. Runx2-dependent bone development. Tissue Eng Part B Rev.
2013;19(3):254-263.
doi: 10.1097/MOH.0000000000000347
doi: 10.1089/ten.TEB.2012.0527
49. Stone HB, Coleman CN, Anscher MS, McBride WH.
Effects of radiation on normal tissue: Consequences and 60. Xie C, Chen Q. Adipokines: New therapeutic target for
mechanisms. Lancet Oncol. 2003;4(9):529-536. osteoarthritis? Curr Rheumatol Rep. 2019;21(12):71.
doi: 10.1016/s1470-2045(03)01191-4 doi: 10.1007/s11926-019-0868-z
50. Dang TN, Taylor JL, Kilroy G, Yu Y, Burk DH, Floyd ZE. 61. Huang L, Li P, Guo L, et al. Zinc finger protein 521 attenuates

Volume 3 Issue 3 (2024) 12 doi: 10.36922/gpd.3260