Page 122 - GPD-4-1

Gene & Protein in Disease Prognostic role of SIRT1 expression in cancer

35. Tan Y, Li B, Peng F, Gong G, Li N. Integrative analysis of et al. Vitamin D induces SIRT1 activation through K610
sirtuins and their prognostic significance in clear cell renal deacetylation in colon cancer. eLife. 2023;12:RP86913.
cell carcinoma. Front Oncol. 2020;10:218.
doi: 10.7554/eLife.86913
doi: 10.3389/fonc.2020.00218
45. Wang TW, Chern E, Hsu CW, Tseng KC, Chao HM. SIRT1-
36. Beyer S, Chen F, Meister S, et al. Sirtuin1 expression and Mediated expression of CD24 and epigenetic suppression
survival in endometrial and clear-cell uterine cancer. of novel tumor suppressor miR-1185-1 increases colorectal
Histochem Cell Biol. 2020;154:189-195. cancer stemness. Cancer Res. 2020;80(23):5257-5269.
doi: 10.1007/s00418-020-01873-x doi: 10.1158/0008-5472.CAN-19-3188
37. Chen F. The Expression of Sirtuin1 and Its Role in Ovarian 46. Yu L, Dong L, Li H, et al. Ubiquitination-mediated degradation
Cancer. Germany: Ludwig Maximilian University of of SIRT1 by SMURF2 suppresses CRC cell proliferation and
Munich; 2022. tumorigenesis. Oncogene. 2020;39(22):4450-4464.
38. Jiang B, Chen JH, Yuan WZ, et al. Prognostic and clinical doi: 10.1038/s41388-020-1298-0
value of Sirt1 expression in gastric cancer: A systematic meta-
analysis. J Huazhong Univ Sci Technol. 2016;36(2):278-284. 47. Lin EI, Tseng LH, Gocke CD, et al. Mutational profiling of
colorectal cancers with microsatellite instability. Oncotarget.
doi: 10.1007/s11596-016-1580-0 2015;6(39):42334-42344.
39. Wu S, Jiang J, Liu J, Wang X, Gan Y, Tang Y. Meta- doi: 10.18632/oncotarget.5997
analysis of SIRT1 expression as a prognostic marker for
overall survival in gastrointestinal cancer. Oncotarget. 48. Dong W, Lu J, Li Y, et al. SIRT1: A novel regulator in
2017;8(37):62589-62599. colorectal cancer. Biomed Pharmacother. 2024;178:117176.
doi: 10.18632/oncotarget.19880 doi: 10.1016/j.biopha.2024.117176
40. Ozcan O, Belli AK, Cetin ES, et al. Upregulation of SIRT1 49. Parmar S, Easwaran H. Genetic and epigenetic dependencies
gene in gastric adenocarcinoma. Turk J Gastroenterol. in colorectal cancer development. Gastroenterol
2019;30(4):326-330. Rep. 2022;10:goac035.
doi: 10.5152/tjg.2019.18550 doi: 10.1093/gastro/goac035
41. Feng AN, Zhang LH, Fan XS, et al. Expression of SIRT1 in 50. Deng Y, Wang Y, Li L, Miao EA, Liu P. Post-translational
gastric cardiac cancer and its clinicopathologic significance. modifications of proteins in cytosolic nucleic acid sensing
Int J Surg Pathol. 2011;19(6):743-750. signaling pathways. Front Immunol. 2022;13:898724.
doi: 10.1177/1066896911412181 doi: 10.3389/fimmu.2022.898724
42. Jiang K, Lyu L, Shen Z, et al. Overexpression of SIRT1 is a 51. Kang JA, Kim YJ, Jang KY, et al. SIRT1 ISGylation accelerates
poor prognostic factor for advanced colorectal cancer. Chin tumor progression by unleashing SIRT1 from the inactive
Med J. 2014;127(11):2021-2024. state to promote its deacetylase activity. Exp Mol Med.
2024;56(3):656-673.
43. Zhou Y, Cheng S, Chen S, Zhao Y. Prognostic and
clinicopathological value of SIRT3 expression in various doi: 10.1038/s12276-024-01194-2
cancers: A systematic review and meta-analysis. Onco 52. Morishita H, Otsuka R, Murakami K, et al. SIRT1 Promotes
Targets Ther. 2018;11:2157-2167.
chemoradiotherapy resistance in esophageal squamous cell
doi: 10.2147/OTT.S157836 carcinoma. Oncology. 2024;102:960-968.
44. García-Martínez JM, Chocarro-Calvo A, Martínez-Useros J, doi: 10.1159/000540247

Volume 4 Issue 1 (2025) 14 doi: 10.36922/gpd.4294